(Q34635917)

3 August 2017

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title

Effect of diet on cancer development: is oxidative DNA damage a biomarker? (English)

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3 August 2017

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1

Barry Halliwell

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3 August 2017

publication date

1 May 2002

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Free Radical Biology and Medicine

3 August 2017

published in

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3 August 2017

volume

32

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3 August 2017

issue

10

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3 August 2017

page(s)

968-974

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Analysis of a form of oxidative DNA damage, 8-hydroxy-2'-deoxyguanosine, as a marker of cellular oxidative stress during carcinogenesis

3 August 2017

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Why and how should we measure oxidative DNA damage in nutritional studies? How far have we come?

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Spontaneous cancer and its possible relationship to oxygen metabolism

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The role of 8-hydroxyguanine in carcinogenesis

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Establishing the significance and optimal intake of dietary antioxidants: the biomarker concept

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Experimental study of oxidative DNA damage

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Urinary 8-oxo-2'-deoxyguanosine--source, significance and supplements.

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DNA oxidation matters: the HPLC-electrochemical detection assay of 8-oxo-deoxyguanosine and 8-oxo-guanine

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7 January 2021

8-Hydroxydeoxyguanosine and 8-hydroxyguanine as biomarkers of oxidative DNA damage

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7 January 2021

Measurement of 8-oxo-2'-deoxyguanosine and 8-oxo-2'-deoxyadenosine in DNA and human urine by high performance liquid chromatography-electrospray tandem mass spectrometry.

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7 January 2021

Fast quantification of the urinary marker of oxidative stress 8-hydroxy-2'-deoxyguanosine using solid-phase extraction and high-performance liquid chromatography with triple-stage quadrupole mass detection

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7 January 2021

8-Oxo-7,8-dihydroguanine and 8-oxo-7,8-dihydro-2'-deoxyguanosine levels in human urine do not depend on diet

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7 January 2021

Hydrolytic elimination of a mutagenic nucleotide, 8-oxodGTP, by human 18-kilodalton protein: sanitization of nucleotide pool

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7 January 2021

Urine 8-oxo-7,8-dihydro-2-deoxyguanosine vs. 5-(hydroxymethyl) uracil as DNA oxidation marker in adriamycin-treated patients

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7 January 2021

Analysis of methylated and oxidized purines in urine by capillary gas chromatography-mass spectrometry

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7 January 2021

Simultaneous determination of five oxidative DNA lesions in human urine

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7 January 2021

Mutagenicity and repair of oxidative DNA damage: insights from studies using defined lesions

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7 January 2021

Genotoxicity of ribo- and deoxyribonucleosides of 8-hydroxyguanine, 5-hydroxycytosine, and 2-hydroxyadenine: induction of SCE in human lymphocytes and mutagenicity in Salmonella typhimurium TA 100.

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7 January 2021

The mutations induced by oxidatively damaged nucleotides, 5-formyl-dUTP and 5-hydroxy-dCTP,in Escherichia coli

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7 January 2021

Correlation of DNA adduct levels with tumor incidence: carcinogenic potency of DNA adducts

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7 January 2021

Tomato consumption modulates oxidative DNA damage in humans

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7 January 2021

Consumption of vegetables reduces genetic damage in humans: first results of a human intervention trial with carotenoid-rich foods.

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7 January 2021

Reduction of oxidative DNA-damage in humans by brussels sprouts.

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7 January 2021

Supplementation with fruit and vegetable extracts may decrease DNA damage in the peripheral lymphocytes of an elderly population

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7 January 2021

Effect of increased vegetable and fruit consumption on markers of oxidative cellular damage

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7 January 2021

No influence of beta carotene on oxidative DNA damage in male smokers

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7 January 2021

No effect of supplementation with vitamin E, ascorbic acid, or coenzyme Q10 on oxidative DNA damage estimated by 8-oxo-7,8-dihydro-2'-deoxyguanosine excretion in smokers.

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7 January 2021

Vitamin C exhibits pro-oxidant properties.

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7 January 2021

Can antioxidant vitamins materially reduce oxidative damage in humans?

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7 January 2021

Long-term effects of vitamin E, vitamin C, and combined supplementation on urinary 7-hydro-8-oxo-2'-deoxyguanosine, serum cholesterol oxidation products, and oxidation resistance of lipids in nondepleted men.

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7 January 2021

Oxidative DNA damage measured in human lymphocytes: large differences between sexes and between countries, and correlations with heart disease mortality rates.

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7 January 2021

Beta-carotene takes a collective beating

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7 January 2021

8-Hydroxydeoxyguanosine in DNA from leukocytes of healthy adults: relationship with cigarette smoking, environmental tobacco smoke, alcohol and coffee consumption

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7 January 2021

Cigarette smoking induces formation of 8-hydroxydeoxyguanosine, one of the oxidative DNA damages in human peripheral leukocytes.

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7 January 2021

Cigarette smoking induces an increase in oxidative DNA damage, 8-hydroxydeoxyguanosine, in a central site of the human lung

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7 January 2021

A multi-biomarker approach to study the effects of smoking on oxidative DNA damage and repair and antioxidative defense mechanisms

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7 January 2021

Mitochondrial damage by the "pro-oxidant" peroxisomal proliferator clofibrate

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7 January 2021

Correlation of individual papilloma latency time with DNA adducts, 8-hydroxy-2'-deoxyguanosine, and the rate of DNA synthesis in the epidermis of mice treated with 7,12-dimethylbenz[alpha]anthracene

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7 January 2021

Nickel(II)-mediated oxidative DNA base damage in renal and hepatic chromatin of pregnant rats and their fetuses. Possible relevance to carcinogenesis

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7 January 2021

Benzo[a]pyrene diol-epoxide-I-DNA and oxidative DNA adducts associated with gastric adenocarcinoma

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7 January 2021

Association between 8-hydroxy-2'-deoxyguanosine levels in DNA of workers highly exposed to asbestos and their clinical data, occupational and non-occupational confounding factors, and cancer

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7 January 2021

Effect of varying dietary fat levels on rat growth and oxidative DNA damage

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7 January 2021

Lung carcinogenesis and formation of 8-hydroxy-deoxyguanosine in mice by diesel exhaust particles

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7 January 2021

High fat diet induced oxidative DNA damage estimated by 8-oxo-7,8-dihydro-2-deoxyguanosine excretion in rats.

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7 January 2021

Chronic infections and inflammatory processes as cancer risk factors: possible role of nitric oxide in carcinogenesis

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7 January 2021

The COX-2 inhibitor nimesulide suppresses superoxide and 8-hydroxy-deoxyguanosine formation, and stimulates apoptosis in mucosa during early colonic inflammation in rats

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7 January 2021

Extensive oxidative DNA damage in hepatocytes of transgenic mice with chronic active hepatitis destined to develop hepatocellular carcinoma

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7 January 2021

Vitamin E reduces chromosomal damage and inhibits hepatic tumor formation in a transgenic mouse model

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7 January 2021

Early oxidative DNA damages and late development of lung cancer in diesel exhaust-exposed rats.

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7 January 2021

Spontaneous tumorigenesis in mice defective in the MTH1 gene encoding 8-oxo-dGTPase

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7 January 2021

DNA base modifications and antioxidant enzyme activities in human benign prostatic hyperplasia.

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7 January 2021

Oxidative DNA damage and cellular sensitivity to oxidative stress in human autoimmune diseases

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7 January 2021

Oxygen radicals, nitric oxide and human inflammatory joint disease

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7 January 2021

Risk of malignancy among patients with rheumatic conditions

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7 January 2021

Oxidative damage to DNA in diabetes mellitus

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7 January 2021

Increased oxidative damage to all DNA bases in patients with type II diabetes mellitus

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7 January 2021

New biomarker evidence of oxidative DNA damage in patients with non-insulin-dependent diabetes mellitus.

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7 January 2021

Diabetes, body size, and risk of endometrial cancer

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7 January 2021

Colorectal cancer: another complication of diabetes mellitus?

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7 January 2021

Anthropometric and other risk factors for ovarian cancer in a case-control study.

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7 January 2021

Superoxide and hydrogen peroxide in relation to mammalian cell proliferation

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7 January 2021

DNA oxidative damage in leukocytes correlates with the severity of HCV-related liver disease: validation in an open population study

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7 January 2021

Effect of endurance exercise on the tissue 8-hydroxy-deoxyguanosine content in dogs.

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7 January 2021

Age and organ dependent spontaneous generation of nuclear 8-hydroxydeoxyguanosine in male Fischer 344 rats.

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7 January 2021

Sensitive detection of 8-hydroxy-2'deoxyguanosine in DNA by 32P-postlabeling assay and the basal levels in rat tissues

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7 January 2021

Detection of endogenous malondialdehyde-deoxyguanosine adducts in human liver

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7 January 2021

Genotoxic lipid peroxidation products: their DNA damaging properties and role in formation of endogenous DNA adducts

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7 January 2021

Novel repair action of vitamin C upon in vivo oxidative DNA damage

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7 January 2021

Mutagenesis by 8-oxoguanine: an enemy within

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7 January 2021

Site-specific DNA damage at GGG sequence by oxidative stress may accelerate telomere shortening

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7 January 2021

Mapping oxidative DNA damage using ligation-mediated polymerase chain reaction technology

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7 January 2021

Antioxidant defence mechanisms: from the beginning to the end (of the beginning).

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7 January 2021

Oxidative stress, human genetic variation, and disease

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7 January 2021

Association between manganese superoxide dismutase (MnSOD) gene polymorphism and breast cancer risk.

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7 January 2021

10.1016/S0891-5849(02)00808-0

Identifiers

DOI

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3 August 2017

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