(Q34642678)

3 August 2017

title

Sorafenib inhibits ERK1/2 and MCL-1(L) phosphorylation levels resulting in caspase-independent cell death in malignant pleural mesothelioma (English)

1 reference

3 August 2017

1 reference

1 reference

Sharyn I Katz

1

0 references

author name string

Lanlan Zhou

2

1 reference

3 August 2017

Grace Chao

3

1 reference

3 August 2017

Charles D Smith

4

1 reference

3 August 2017

Thomas Ferrara

5

1 reference

3 August 2017

Wenge Wang

6

1 reference

3 August 2017

David T Dicker

7

1 reference

3 August 2017

Wafik S El-Deiry

8

1 reference

3 August 2017

language of work or name

1 reference

2 December 2009

1 reference

Cancer Biology and Therapy

3 August 2017

published in

1 reference

3 August 2017

volume

8

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3 August 2017

issue

24

1 reference

3 August 2017

page(s)

2406-2416

1 reference

Vesicular stomatitis virus induces apoptosis primarily through Bak rather than Bax by inactivating Mcl-1 and Bcl-XL

3 August 2017

cites work

1 reference

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7 July 2018

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Tumour cell survival signalling by the ERK1/2 pathway

7 July 2018

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Survival of pleural malignant mesothelioma in Italy: a population-based study

7 July 2018

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Systemic treatments for mesothelioma: standard and novel

7 July 2018

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Review of pemetrexed in combination with cisplatin for the treatment of malignant pleural mesothelioma

7 July 2018

1 reference

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Enhanced antitumor therapy by inhibition of p21waf1 in human malignant mesothelioma

7 July 2018

1 reference

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Asbestos induces doxorubicin resistance in MM98 mesothelioma cells via HIF-1alpha.

7 July 2018

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7 July 2018

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Inhibition of c-Src expression and activation in malignant pleural mesothelioma tissues leads to apoptosis, cell cycle arrest, and decreased migration and invasion

7 July 2018

1 reference

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Translational repression of MCL-1 couples stress-induced eIF2 alpha phosphorylation to mitochondrial apoptosis initiation

7 July 2018

1 reference

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ERK1/2-dependent phosphorylation of BimEL promotes its rapid dissociation from Mcl-1 and Bcl-xL

7 July 2018

1 reference

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Degradation of Mcl-1 by beta-TrCP mediates glycogen synthase kinase 3-induced tumor suppression and chemosensitization

7 July 2018

1 reference

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The cell-adhesion and signaling molecule PECAM-1 is a molecular mediator of resistance to genotoxic chemotherapy.

7 July 2018

1 reference

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Glycogen synthase kinase-3 regulates mitochondrial outer membrane permeabilization and apoptosis by destabilization of MCL-1

7 July 2018

1 reference

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Asbestos and mesothelioma: worldwide trends

7 July 2018

1 reference

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Induction of stem cell factor/c-Kit/slug signal transduction in multidrug-resistant malignant mesothelioma cells

7 July 2018

1 reference

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FLIP overexpression inhibits death receptor-induced apoptosis in malignant mesothelial cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3052759

MCL1 is phosphorylated in the PEST region and stabilized upon ERK activation in viable cells, and at additional sites with cytotoxic okadaic acid or taxol

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3052759

Induction of apoptosis and chemosensitization of mesothelioma cells by Bcl-2 and Bcl-xL antisense treatment.

7 July 2018

1 reference

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Inhibitor of apoptosis protein-1 promotes tumor cell survival in mesothelioma

7 July 2018

1 reference

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Antisense therapy for malignant mesothelioma with oligonucleotides targeting the bcl-xl gene product

7 July 2018

1 reference

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Bcl-xL promotes the open configuration of the voltage-dependent anion channel and metabolite passage through the outer mitochondrial membrane

7 July 2018

1 reference

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BAD Ser-155 phosphorylation regulates BAD/Bcl-XL interaction and cell survival

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3052759

Bcl-xL regulates apoptosis by heterodimerization-dependent and -independent mechanisms

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3052759

Anti-apoptotic Bcl-XL protein in complex with BH3 peptides of pro-apoptotic Bak, Bad, and Bim proteins: comparative molecular dynamics simulations.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3052759

Results of a Phase I trial of sorafenib (BAY 43-9006) in combination with doxorubicin in patients with refractory solid tumors

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3052759

TAT-mediated delivery of Bcl-xL protein is neuroprotective against neonatal hypoxic-ischemic brain injury via inhibition of caspases and AIF.

26 October 2018

1 reference

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Apoptosis regulation and drug resistance in malignant pleural mesothelioma.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3052759

Quantitative evaluation of the apoptosis regulating genes Survivin, Bcl-2 and Bax in inflammatory and malignant pleural lesions.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3052759

Identification of a novel Bcl-xL phosphorylation site regulating the sensitivity of taxol- or 2-methoxyestradiol-induced apoptosis

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3052759

Acceleration of apoptotic cell death after the cleavage of Bcl-XL protein by caspase-3-like proteases

26 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20038816

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Mcl-1 interacts with truncated Bid and inhibits its induction of cytochrome c release and its role in receptor-mediated apoptosis

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20038816

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.4161/CBT.8.24.10824

1 reference

3 August 2017

1 reference

3 August 2017

1 reference