(Q40537978)

English

MCL1 is phosphorylated in the PEST region and stabilized upon ERK activation in viable cells, and at additional sites with cytotoxic okadaic acid or taxol

scientific article published on July 2004

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scholarly article

1 reference

Europe PubMed Central

21 September 2017

MCL1 is phosphorylated in the PEST region and stabilized upon ERK activation in viable cells, and at additional sites with cytotoxic okadaic acid or taxol (English)

1 reference

Europe PubMed Central

21 September 2017

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phosphorylation

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author name string

Aaron M Domina

1

1 reference

Europe PubMed Central

21 September 2017

Julie A Vrana

2

1 reference

Europe PubMed Central

21 September 2017

Mark A Gregory

3

1 reference

Europe PubMed Central

21 September 2017

Stephen R Hann

4

1 reference

Europe PubMed Central

21 September 2017

Ruth W Craig

5

1 reference

Europe PubMed Central

21 September 2017

language of work or name

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publication date

1 July 2004

1 reference

Europe PubMed Central

21 September 2017

1 reference

Europe PubMed Central

21 September 2017

23

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Europe PubMed Central

21 September 2017

5301-5315

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Europe PubMed Central

21 September 2017

31

1 reference

Europe PubMed Central

21 September 2017

https://scigraph.springernature.com/pub.10.1038/sj.onc.1207692

0 references

Exon skipping in Mcl-1 results in a bcl-2 homology domain 3 only gene product that promotes cell death

1 reference

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21 January 2018

Mono- and multisite phosphorylation enhances Bcl2's antiapoptotic function and inhibition of cell cycle entry functions

1 reference

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21 January 2018

Survival function of ERK1/2 as IL-3-activated, staurosporine-resistant Bcl2 kinases

1 reference

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21 January 2018

Novel role for JNK as a stress-activated Bcl2 kinase

1 reference

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21 January 2018

Dephosphorylation targets Bcl-2 for ubiquitin-dependent degradation: a link between the apoptosome and the proteasome pathway.

1 reference

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21 January 2018

Myeloid cell leukemia 1 is phosphorylated through two distinct pathways, one associated with extracellular signal-regulated kinase activation and the other with G2/M accumulation or protein phosphatase 1/2A inhibition

1 reference

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21 January 2018

Inhibition of cell proliferation and cell cycle progression by specific inhibition of basal JNK activity: evidence that mitotic Bcl-2 phosphorylation is JNK-independent

1 reference

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21 January 2018

Phosphorylation by Glycogen Synthase Kinase-3 Controls c-Myc Proteolysis and Subnuclear Localization

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207692

21 January 2018

p70S6 kinase signals cell survival as well as growth, inactivating the pro-apoptotic molecule BAD

1 reference

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21 January 2018

Phosphorylation and inactivation of myeloid cell leukemia 1 by JNK in response to oxidative stress

1 reference

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21 January 2018

Bcl-2 phosphorylation required for anti-apoptosis function

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207692

21 January 2018

MCL1, a gene expressed in programmed myeloid cell differentiation, has sequence similarity to BCL2

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207692

21 January 2018

Generation of destabilized green fluorescent protein as a transcription reporter

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207692

21 January 2018

Bcl-2 undergoes phosphorylation by c-Jun N-terminal kinase/stress-activated protein kinases in the presence of the constitutively active GTP-binding protein Rac1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207692

21 January 2018

BCL-2 and MCL-1 expression in Chinese hamster ovary cells inhibits intracellular acidification and apoptosis induced by staurosporine

1 reference

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21 January 2018

Regulation of bad phosphorylation and association with Bcl-x(L) by the MAPK/Erk kinase

1 reference

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21 January 2018

Deletion of the loop region of Bcl-2 completely blocks paclitaxel-induced apoptosis

1 reference

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21 January 2018

Chemically induced premature mitosis: differential response in rodent and human cells and the relationship to cyclin B synthesis and p34cdc2/cyclin B complex formation

1 reference

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21 January 2018

Analysis of the structure, transcripts, and protein products of bcl-2, the gene involved in human follicular lymphoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207692

21 January 2018

Phosphorylation of Bcl-2 in G2/M phase-arrested cells following photodynamic therapy with hypericin involves a CDK1-mediated signal and delays the onset of apoptosis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207692

21 January 2018

The intracellular distribution and pattern of expression of Mcl-1 overlap with, but are not identical to, those of Bcl-2

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207692

21 January 2018

In vivo localisation and stability of human Mcl-1 using green fluorescent protein (GFP) fusion proteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207692

7 January 2021

based on heuristic

inferred from DOI database lookup

Unwinding the loop of Bcl-2 phosphorylation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207692

7 January 2021

based on heuristic

inferred from DOI database lookup

Posttranslational modification of Bcl-2 facilitates its proteasome-dependent degradation: molecular characterization of the involved signaling pathway.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207692

7 January 2021

based on heuristic

inferred from DOI database lookup

Cloning and characterization of a novel nuclear Bcl-2 family protein, zfMcl-1a, in zebrafish embryo.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207692

7 January 2021

based on heuristic

inferred from DOI database lookup

Turnover of cyclin E by the ubiquitin-proteasome pathway is regulated by cdk2 binding and cyclin phosphorylation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207692

7 January 2021

based on heuristic

inferred from DOI database lookup

MCL1 provides a window on the role of the BCL2 family in cell proliferation, differentiation and tumorigenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207692

7 January 2021

based on heuristic

inferred from DOI database lookup

DNA damage response and MCL-1 destruction initiate apoptosis in adenovirus-infected cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207692

7 January 2021

based on heuristic

inferred from DOI database lookup

Vinblastine-induced phosphorylation of Bcl-2 and Bcl-XL is mediated by JNK and occurs in parallel with inactivation of the Raf-1/MEK/ERK cascade

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207692

7 January 2021

based on heuristic

inferred from DOI database lookup

Phosphorylation of Bcl-2 protein by CDC2 kinase during G2/M phases and its role in cell cycle regulation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207692

7 January 2021

based on heuristic

inferred from DOI database lookup

c-Myc proteolysis by the ubiquitin-proteasome pathway: stabilization of c-Myc in Burkitt's lymphoma cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207692

7 January 2021

based on heuristic

inferred from DOI database lookup

Phosphorylation-dependent ubiquitination of cyclin E by the SCFFbw7 ubiquitin ligase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207692

7 January 2021

based on heuristic

inferred from DOI database lookup

Phosphorylation of Bim-EL by Erk1/2 on serine 69 promotes its degradation via the proteasome pathway and regulates its proapoptotic function.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207692

7 January 2021

based on heuristic

inferred from DOI database lookup

Hierarchical phosphorylation at N-terminal transformation-sensitive sites in c-Myc protein is regulated by mitogens and in mitosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207692

7 January 2021

based on heuristic

inferred from DOI database lookup

Rum1, an inhibitor of cyclin-dependent kinase in fission yeast, is negatively regulated by mitogen-activated protein kinase-mediated phosphorylation at Ser and Thr residues

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207692

7 January 2021

based on heuristic

inferred from DOI database lookup

Reduced ubiquitin-dependent degradation of c-Jun after phosphorylation by MAP kinases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207692

7 January 2021

based on heuristic

inferred from DOI database lookup

Elimination of Mcl-1 is required for the initiation of apoptosis following ultraviolet irradiation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207692

7 January 2021

based on heuristic

inferred from DOI database lookup

Development and maintenance of B and T lymphocytes requires antiapoptotic MCL-1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207692

7 January 2021

based on heuristic

inferred from DOI database lookup

Mitotic phosphorylation of Bcl-2 during normal cell cycle progression and Taxol-induced growth arrest

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207692

7 January 2021

based on heuristic

inferred from DOI database lookup

Ras enhances Myc protein stability.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207692

7 January 2021

based on heuristic

inferred from DOI database lookup

Multiple Ras-dependent phosphorylation pathways regulate Myc protein stability.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207692

7 January 2021

based on heuristic

inferred from DOI database lookup

Involvement of microtubules in the regulation of Bcl2 phosphorylation and apoptosis through cyclic AMP-dependent protein kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207692

7 January 2021

based on heuristic

inferred from DOI database lookup

p53 mediates bcl-2 phosphorylation and apoptosis via activation of the Cdc42/JNK1 pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207692

7 January 2021

based on heuristic

inferred from DOI database lookup

Expression of the antiapoptotic MCL1 gene product is regulated by a mitogen activated protein kinase-mediated pathway triggered through microtubule disruption and protein kinase C.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207692

7 January 2021

based on heuristic

inferred from DOI database lookup

Regulation of MCL1 through a serum response factor/Elk-1-mediated mechanism links expression of a viability-promoting member of the BCL2 family to the induction of hematopoietic cell differentiation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207692

7 January 2021

based on heuristic

inferred from DOI database lookup

Ca2+-induced apoptosis through calcineurin dephosphorylation of BAD

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207692

7 January 2021

based on heuristic

inferred from DOI database lookup

BCL-2 is phosphorylated and inactivated by an ASK1/Jun N-terminal protein kinase pathway normally activated at G(2)/M.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207692

7 January 2021

based on heuristic

inferred from DOI database lookup

MCL-1, a member of the BLC-2 family, is induced rapidly in response to signals for cell differentiation or death, but not to signals for cell proliferation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207692

7 January 2021

based on heuristic

inferred from DOI database lookup

MCL1 transgenic mice exhibit a high incidence of B-cell lymphoma manifested as a spectrum of histologic subtypes.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207692

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1038/SJ.ONC.1207692

1 reference

Europe PubMed Central

21 September 2017

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release_xu5ta4zcnnec3mjqpwh6ks67yu

1 reference

https://api.fatcat.wiki/v0/release/xu5ta4zcnnec3mjqpwh6ks67yu

24 November 2022

based on heuristic

mapped directly with Wikidata item

1 reference

Europe PubMed Central

21 September 2017

ResearchGate publication ID

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