(Q44052586)

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Phosphorylation of Bcl-2 in G2/M phase-arrested cells following photodynamic therapy with hypericin involves a CDK1-mediated signal and delays the onset of apoptosis.

scientific article published on 5 July 2002

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10 November 2019

Phosphorylation of Bcl-2 in G2/M phase-arrested cells following photodynamic therapy with hypericin involves a CDK1-mediated signal and delays the onset of apoptosis (English)

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10 November 2019

phosphorylation

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Patrizia Agostinis

8

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10 November 2019

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10 November 2019

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Annelies Vantieghem

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10 November 2019

Yan Xu

2

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10 November 2019

Zerihun Assefa

3

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10 November 2019

Jacques Piette

4

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10 November 2019

Jackie R Vandenheede

5

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10 November 2019

Wilfried Merlevede

6

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10 November 2019

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5 July 2002

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10 November 2019

Journal of Biological Chemistry

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10 November 2019

277

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10 November 2019

40

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10 November 2019

37718-37731

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10 November 2019

Photodynamic therapy in oncology: mechanisms and clinical use.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204348200

21 January 2018

Mechanism of photodynamic therapy-induced cell death

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204348200

21 January 2018

Hypericin in cancer treatment: more light on the way.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204348200

21 January 2018

Signaling pathways in cell death and survival after photodynamic therapy

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204348200

21 January 2018

Mechanism of colon cancer cell apoptosis mediated by pyropheophorbide-a methylester photosensitization

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204348200

21 January 2018

Hypericin-induced photosensitization of HeLa cells leads to apoptosis or necrosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204348200

21 January 2018

Different pathways mediate cytochrome c release after photodynamic therapy with hypericin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204348200

21 January 2018

Cellular photodestruction induced by hypericin in AY-27 rat bladder carcinoma cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204348200

21 January 2018

The Activation of the c-Jun N-terminal Kinase and p38 Mitogen-activated Protein Kinase Signaling Pathways Protects HeLa Cells from Apoptosis Following Photodynamic Therapy with Hypericin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204348200

21 January 2018

Over-expression of Bcl-2 does not protect cells from hypericin photo-induced mitochondrial membrane depolarization, but delays subsequent events in the apoptotic pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204348200

21 January 2018

The Bcl-2 protein family: arbiters of cell survival

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204348200

21 January 2018

The anti-apoptosis function of Bcl-2 can be genetically separated from its inhibitory effect on cell cycle entry

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204348200

21 January 2018

Bcl-2 retards cell cycle entry through p27(Kip1), pRB relative p130, and altered E2F regulation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204348200

21 January 2018

Unwinding the loop of Bcl-2 phosphorylation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204348200

21 January 2018

A functional role for mitochondrial protein kinase Calpha in Bcl2 phosphorylation and suppression of apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204348200

21 January 2018

Involvement of microtubules in the regulation of Bcl2 phosphorylation and apoptosis through cyclic AMP-dependent protein kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204348200

21 January 2018

Survival function of ERK1/2 as IL-3-activated, staurosporine-resistant Bcl2 kinases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204348200

21 January 2018

NGF withdrawal induces apoptosis in CESS B cell line through p38 MAPK activation and Bcl-2 phosphorylation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204348200

21 January 2018

Nerve growth factor inhibits apoptosis in memory B lymphocytes via inactivation of p38 MAPK, prevention of Bcl-2 phosphorylation, and cytochrome c release.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204348200

21 January 2018

Novel role for JNK as a stress-activated Bcl2 kinase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204348200

21 January 2018

Bcl-2 undergoes phosphorylation by c-Jun N-terminal kinase/stress-activated protein kinases in the presence of the constitutively active GTP-binding protein Rac1.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204348200

21 January 2018

BCL-2 is phosphorylated and inactivated by an ASK1/Jun N-terminal protein kinase pathway normally activated at G(2)/M.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204348200

21 January 2018

Deletion of the loop region of Bcl-2 completely blocks paclitaxel-induced apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204348200

21 January 2018

Phosphorylation of Bcl-2 is a marker of M phase events and not a determinant of apoptosis.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204348200

21 January 2018

Microtubule-targeting drugs induce Bcl-2 phosphorylation and association with Pin1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204348200

21 January 2018

Bcl-2 phosphorylation required for anti-apoptosis function

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204348200

21 January 2018

Angiotensin type 2 receptor dephosphorylates Bcl-2 by activating mitogen-activated protein kinase phosphatase-1 and induces apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204348200

21 January 2018

Inactivation of Bcl-2 by phosphorylation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204348200

21 January 2018

Bcl-2 overexpression blocks caspase activation and downstream apoptotic events instigated by photodynamic therapy

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204348200

21 January 2018

Involvement of Bcl-2 and Bax in photodynamic therapy-mediated apoptosis. Antisense Bcl-2 oligonucleotide sensitizes RIF 1 cells to photodynamic therapy apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204348200

21 January 2018

Differential cytotoxic effects induced after photosensitization by hypericin.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204348200

21 January 2018

Differential stimulation of ERK and JNK activities by ultraviolet B irradiation and epidermal growth factor in human keratinocytes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204348200

21 January 2018

NIPP1-mediated interaction of protein phosphatase-1 with CDC5L, a regulator of pre-mRNA splicing and mitotic entry

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204348200

21 January 2018

Molecular effects of paclitaxel: myths and reality (a critical review).

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204348200

21 January 2018

Activation of stress-activated protein kinase by MEKK1 phosphorylation of its activator SEK1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204348200

21 January 2018

Principles of CDK regulation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204348200

21 January 2018

Biochemical and cellular effects of roscovitine, a potent and selective inhibitor of the cyclin-dependent kinases cdc2, cdk2 and cdk5.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204348200

21 January 2018

Indirubins inhibit glycogen synthase kinase-3 beta and CDK5/p25, two protein kinases involved in abnormal tau phosphorylation in Alzheimer's disease. A property common to most cyclin-dependent kinase inhibitors?

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204348200

21 January 2018

The Bcl-2 family and cell death regulation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204348200

21 January 2018

Human cyclins A and B1 are differentially located in the cell and undergo cell cycle-dependent nuclear transport

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204348200

21 January 2018

Tubulin as a target for anticancer drugs: agents which interact with the mitotic spindle

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204348200

21 January 2018

Lysosomes and microtubules as targets for photochemotherapy of cancer

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204348200

21 January 2018

Photodynamic damage to HeLa cell microtubules induced by thiazine dyes.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204348200

21 January 2018

Taxol suppresses dynamics of individual microtubules in living human tumor cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204348200

21 January 2018

Phosphorylation of Bcl2 and regulation of apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204348200

21 January 2018

Phosphorylation-dependent prolyl isomerization: a novel signaling regulatory mechanism.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204348200

21 January 2018

Identifiers

10.1074/JBC.M204348200

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12101183%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

release_p6h5fknknffitdejp7nuhf7bri

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https://api.fatcat.wiki/v0/release/p6h5fknknffitdejp7nuhf7bri

24 November 2022

based on heuristic

mapped directly with Wikidata item

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Europe PubMed Central

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10 November 2019

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