(Q34652444)

English

3'-Azido-3'-deoxythymidine (AZT) inhibits thymidine phosphorylation in isolated rat liver mitochondria: a possible mechanism of AZT hepatotoxicity

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scholarly article

1 reference

Europe PubMed Central

3 August 2017

3'-Azido-3'-deoxythymidine (AZT) inhibits thymidine phosphorylation in isolated rat liver mitochondria: a possible mechanism of AZT hepatotoxicity (English)

1 reference

Europe PubMed Central

3 August 2017

phosphorylation

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

author name string

Matthew D Lynx

1

1 reference

Europe PubMed Central

3 August 2017

Alice T Bentley

2

1 reference

Europe PubMed Central

3 August 2017

Edward E McKee

3

1 reference

Europe PubMed Central

3 August 2017

language of work or name

0 references

publication date

10 February 2006

1 reference

Europe PubMed Central

3 August 2017

Biochemical Pharmacology

1 reference

Europe PubMed Central

3 August 2017

71

1 reference

Europe PubMed Central

3 August 2017

9

1 reference

Europe PubMed Central

3 August 2017

1342-1348

1 reference

Europe PubMed Central

3 August 2017

Haematological changes in adults receiving a zidovudine-containing HAART regimen in combination with cotrimoxazole in Côte d'Ivoire

1 reference

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7 July 2018

Adverse effects of antiretroviral therapy in HIV-1 infected children

1 reference

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DNA precursor asymmetries in mammalian tissue mitochondria and possible contribution to mutagenesis through reduced replication fidelity.

1 reference

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Phosphorylation of thymidine and AZT in heart mitochondria: elucidation of a novel mechanism of AZT cardiotoxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472706

7 July 2018

Mitochondrial deoxyribonucleoside triphosphate pools in thymidine kinase 2 deficiency

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472706

7 July 2018

mtDNA depletion myopathy: elucidation of the tissue specificity in the mitochondrial thymidine kinase (TK2) deficiency

1 reference

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7 July 2018

Mutant mitochondrial thymidine kinase in mitochondrial DNA depletion myopathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472706

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The deoxyguanosine kinase gene is mutated in individuals with depleted hepatocerebral mitochondrial DNA

1 reference

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Toxicity of antiviral nucleoside analogs and the human mitochondrial DNA polymerase.

1 reference

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Differential effects of antiretroviral nucleoside analogs on mitochondrial function in HepG2 cells

1 reference

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Human thymidine kinase 2: molecular cloning and characterisation of the enzyme activity with antiviral and cytostatic nucleoside substrates

1 reference

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7 July 2018

Structure of thymidylate kinase reveals the cause behind the limiting step in AZT activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472706

7 July 2018

Physiological concentrations of purines and pyrimidines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472706

7 July 2018

Effects of antiviral nucleoside analogs on human DNA polymerases and mitochondrial DNA synthesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472706

7 July 2018

Metabolic abnormalities in skeletal muscle of patients receiving zidovudine therapy observed by 31P in vivo magnetic resonance spectroscopy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472706

7 July 2018

Mitochondrial toxicity of antiviral drugs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472706

7 July 2018

Regulation of thymidine kinase activity in the cell cycle by a labile protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472706

7 July 2018

Mitochondrial myopathy caused by long-term zidovudine therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472706

7 July 2018

Zidovudine myopathy: a distinctive disorder associated with mitochondrial dysfunction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472706

7 July 2018

Depletion of muscle mitochondrial DNA in AIDS patients with zidovudine-induced myopathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472706

7 July 2018

Zidovudine induces molecular, biochemical, and ultrastructural changes in rat skeletal muscle mitochondria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472706

7 July 2018

Site specific alterations of adipose tissue mitochondria in 3'-azido-3'-deoxythymidine (AZT)-treated rats: an early stage in lipodystrophy?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472706

26 October 2018

Dilated cardiomyopathy in an adult human immunodeficiency virus type 1-positive patient treated with a zidovudine-containing antiretroviral regimen

1 reference

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26 October 2018

Zidovudine phosphorylation and mitochondrial toxicity in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1472706

26 October 2018

Differential incorporation and removal of antiviral deoxynucleotides by human DNA polymerase gamma

1 reference

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26 October 2018

Cloning and characterization of the multisubstrate deoxyribonucleoside kinase of Drosophila melanogaster

1 reference

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26 October 2018

Zidovudine-induced mitochondrial disorder with massive liver steatosis, myopathy, lactic acidosis, and mitochondrial DNA depletion.

1 reference

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Cellular and mitochondrial toxicity of zidovudine (AZT), didanosine (ddI) and zalcitabine (ddC) on cultured human muscle cells

1 reference

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26 October 2018

Early features of zidovudine-associated myopathy: histopathological findings and clinical correlations

1 reference

https://pubmed.ncbi.nlm.nih.gov/16472780

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Massive hepatic steatosis and lactic acidosis in a patient with AIDS who was receiving zidovudine

1 reference

https://pubmed.ncbi.nlm.nih.gov/16472780

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hepatic Morphological alterations induced by zidovudine (ZDV) in an experimental model

1 reference

https://pubmed.ncbi.nlm.nih.gov/16472780

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondria as Cell Targets of AZT (Zidovudine)

1 reference

https://pubmed.ncbi.nlm.nih.gov/16472780

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The bottleneck in AZT activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/16472780

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.BCP.2006.01.003

1 reference

Europe PubMed Central

3 August 2017

1 reference

Europe PubMed Central

3 August 2017

1 reference

Europe PubMed Central

3 August 2017

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0 references

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