(Q34654034)

3 August 2017

title

IA-2 autoantibodies in incident type I diabetes patients are associated with a polyadenylation signal polymorphism in GIMAP5. (English)

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J Ludvigsson

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3 August 2017

J Graham

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Ingrid Kockum

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I Kockum

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Lennarth Nyström

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object named as

Lennarth Nyström

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3 August 2017

J-H Shin

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M Janer

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B McNeney

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S Blay

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K Deutsch

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C B Sanjeevi

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A Lernmark

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Swedish Childhood Diabetes Study Group

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Diabetes Incidence in Sweden Study Group

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Hans Arnqvist

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Elizabeth Björck

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Jan Eriksson

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Lars Olof Ohlson

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Bengt Scherstén

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Jan Ostman

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M Aili

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L E Bååth

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E Carlsson

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H Edenwall

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G Forsander

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B W Granström

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I Gustavsson

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R Hanås

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L Hellenberg

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H Hellgren

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E Holmberg

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H Hörnell

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Sten-A Ivarsson

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C Johansson

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G Jonsell

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K Kockum

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B Lindblad

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A Lindh

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U Myrdal

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J Neiderud

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K Segnestam

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S Sjöblad

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L Skogsberg

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L Strömberg

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U Ståhle

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B Thalme

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K Tullus

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T Tuvemo

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M Wallensteen

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O Westphal

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J Aman

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publication date

19 July 2007

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3 August 2017

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volume

8

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3 August 2017

issue

6

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3 August 2017

page(s)

503-512

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https://scigraph.springernature.com/pub.10.1038/sj.gene.6364413

3 August 2017

exact match

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Fine mapping, gene content, comparative sequencing, and expression analyses support Ctla4 and Nramp1 as candidates for Idd5.1 and Idd5.2 in the nonobese diabetic mouse.

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7 January 2021

Long-term risk of IDDM in first-degree relatives of patients with IDDM

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The Swedish childhood diabetes study--results from a nine year case register and a one year case-referent study indicating that type 1 (insulin-dependent) diabetes mellitus is associated with both type 2 (non-insulin-dependent) diabetes mellitus and

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beta-Cell death during progression to diabetes

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Type 1 diabetes: evidence for susceptibility loci from four genome-wide linkage scans in 1,435 multiplex families.

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7 January 2021

A Polymorphic Locus Near the Human Insulin Gene Is Associated with Insulin-dependent Diabetes Melliitus

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Remapping the insulin gene/IDDM2 locus in type 1 diabetes.

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The CTLA-4 gene region of chromosome 2q33 is linked to, and associated with, type 1 diabetes. Belgian Diabetes Registry

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Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease

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7 January 2021

A functional variant of lymphoid tyrosine phosphatase is associated with type I diabetes

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7 January 2021

Genetic mapping at 3-kilobase resolution reveals inositol 1,4,5-triphosphate receptor 3 as a risk factor for type 1 diabetes in Sweden

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7 January 2021

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7 January 2021

Seven regions of the genome show evidence of linkage to type 1 diabetes in a consensus analysis of 767 multiplex families

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7 January 2021

A genomewide scan for type 1-diabetes susceptibility in Scandinavian families: identification of new loci with evidence of interactions

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7 January 2021

Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls

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Autoimmune type 1 diabetes: resolved and unresolved issues

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Resistance alleles at two non-major histocompatibility complex-linked insulin-dependent diabetes loci on chromosome 3, Idd3 and Idd10, protect nonobese diabetic mice from diabetes

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7 January 2021

Lymphopenia in the BB rat model of type 1 diabetes is due to a mutation in a novel immune-associated nucleotide (Ian)-related gene

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7 January 2021

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The diabetes-prone BB rat carries a frameshift mutation in Ian4, a positional candidate of Iddm1

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7 January 2021

Patterns of variant polyadenylation signal usage in human genes

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Assessing the probability that a positive report is false: an approach for molecular epidemiology studies

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Haplotype tag single nucleotide polymorphism analysis of the human orthologues of the rat type 1 diabetes genes Ian4 (Lyp/Iddm1) and Cblb.

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7 January 2021

Combined positivity for HLA DQ2/DQ8 and IA-2 antibodies defines population at high risk of developing type 1 diabetes

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7 January 2021

Genetic effects on age-dependent onset and islet cell autoantibody markers in type 1 diabetes

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7 January 2021

The human GIMAP5 gene has a common polyadenylation polymorphism increasing risk to systemic lupus erythematosus

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Alternative poly(A) site selection in complex transcription units: means to an end?

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The 3' untranslated region of messenger RNA: A molecular 'hotspot' for pathology?

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Irod/Ian5: an inhibitor of gamma-radiation- and okadaic acid-induced apoptosis

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IAN family critically regulates survival and development of T lymphocytes

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7 January 2021

Both Gimap5 and the diabetogenic BBDP allele of Gimap5 induce apoptosis in T cells

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7 January 2021

Autoantibodies in diabetes

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7 January 2021

The lymphocyte guard-IANs: regulation of lymphocyte survival by IAN/GIMAP family proteins

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7 January 2021

The effect of HLA class II, insulin and CTLA4 gene regions on the development of humoral beta cell autoimmunity

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Lymphoid tyrosine phosphatase (LYP/PTPN22) Arg620Trp variant regulates insulin autoimmunity and progression to type 1 diabetes

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7 January 2021

Islet Cell and Thyrogastric Antibodies in 633 Consecutive 15- to 34-Yr-Old Patients in the Diabetes Incidence Study in Sweden

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7 January 2021

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Quantitative assay using recombinant human islet glutamic acid decarboxylase (GAD65) shows that 64K autoantibody positivity at onset predicts diabetes type

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7 January 2021

Molecular cloning and identification of a receptor-type protein tyrosine phosphatase, IA-2, from human insulinoma

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7 January 2021

Autoantibodies to protein tyrosine phosphatase-like proteins in type I diabetes. Overlapping specificities to phogrin and ICA512/IA-2.

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7 January 2021

Prolonged incubation in the two-colour immunofluorescence test increases the prevalence and titres of islet cell antibodies in type 1 (insulin-dependent) diabetes mellitus

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7 January 2021

Serum exchange and use of dilutions have improved precision of measurement of islet cell antibodies.

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7 January 2021

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7 January 2021

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7 January 2021

PolyA_DB: a database for mammalian mRNA polyadenylation

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7 January 2021

Identifiers

DOI

10.1038/SJ.GENE.6364413

1 reference

Dimensions Publication ID

3 August 2017

1045920172

0 references

Fatcat ID

release_vftkgpfsbnccxakcj2bvh4px3e

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/vftkgpfsbnccxakcj2bvh4px3e

24 November 2022

mapped directly with Wikidata item

1 reference