(Q34656377)

English

Farnesol decreases serum triglycerides in rats: identification of mechanisms including up-regulation of PPARalpha and down-regulation of fatty acid synthase in hepatocytes

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scholarly article

1 reference

Europe PubMed Central

3 August 2017

Farnesol decreases serum triglycerides in rats: identification of mechanisms including up-regulation of PPARalpha and down-regulation of fatty acid synthase in hepatocytes (English)

1 reference

Europe PubMed Central

3 August 2017

0 references

1 reference

based on heuristic

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author name string

Robin E Duncan

1

1 reference

Europe PubMed Central

3 August 2017

Michael C Archer

2

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Europe PubMed Central

3 August 2017

publication date

29 May 2008

1 reference

Europe PubMed Central

3 August 2017

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Europe PubMed Central

3 August 2017

43

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Europe PubMed Central

3 August 2017

7

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Europe PubMed Central

3 August 2017

619-627

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Europe PubMed Central

3 August 2017

https://scigraph.springernature.com/pub.10.1007/s11745-008-3192-3

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Farnesol and geraniol chemopreventive activities during the initial phases of hepatocarcinogenesis involve similar actions on cell proliferation and DNA damage, but distinct actions on apoptosis, plasma cholesterol and HMGCoA reductase

1 reference

https://pubmed.ncbi.nlm.nih.gov/18509688

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Androgens stimulate fatty acid synthase in the human prostate cancer cell line LNCaP.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18509688

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin activates the rat sterol-regulatory-element-binding protein 1c (SREBP-1c) promoter through the combinatorial actions of SREBP, LXR, Sp-1 and NF-Y cis-acting elements

1 reference

https://pubmed.ncbi.nlm.nih.gov/18509688

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Squalene synthase-deficient mutant of Chinese hamster ovary cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/18509688

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of atorvastatin, simvastatin, and lovastatin on the metabolism of cholesterol and triacylglycerides in HepG2 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/18509688

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enhancement of insulin signaling through inhibition of tissue lipid accumulation by activation of peroxisome proliferator-activated receptor (PPAR) alpha in obese mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18509688

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Farnesol stimulates differentiation in epidermal keratinocytes via PPARalpha

1 reference

https://pubmed.ncbi.nlm.nih.gov/18509688

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sorting out the roles of PPAR alpha in energy metabolism and vascular homeostasis

1 reference

https://pubmed.ncbi.nlm.nih.gov/18509688

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A model of insulin resistance and nonalcoholic steatohepatitis in rats: role of peroxisome proliferator-activated receptor-alpha and n-3 polyunsaturated fatty acid treatment on liver injury.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18509688

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

SREBP-1c mediates the retinoid-dependent increase in fatty acid synthase promoter activity in HepG2.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18509688

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hypertriglyceridemia and cardiovascular risk reduction.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18509688

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased hepatic VLDL secretion, lipogenesis, and SREBP-1 expression in the corpulent JCR:LA-cp rat.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18509688

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase degradation by the nonsterol mevalonate metabolite farnesol in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/18509688

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

RPR 107393, a potent squalene synthase inhibitor and orally effective cholesterol-lowering agent: comparison with inhibitors of HMG-CoA reductase

1 reference

https://pubmed.ncbi.nlm.nih.gov/18509688

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of fatty acid synthesis by farnesyl pyrophosphate

1 reference

https://pubmed.ncbi.nlm.nih.gov/18509688

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isoprenoids suppress the growth of murine B16 melanomas in vitro and in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/18509688

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fatty acid regulation of very low density lipoprotein production

1 reference

https://pubmed.ncbi.nlm.nih.gov/18509688

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Farnesol as a regulator of HMG-CoA reductase degradation: characterization and role of farnesyl pyrophosphatase

1 reference

https://pubmed.ncbi.nlm.nih.gov/18509688

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased hepatic lipogenesis but decreased expression of lipogenic gene in adipose tissue in human obesity

1 reference

https://pubmed.ncbi.nlm.nih.gov/18509688

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Postprandial de novo lipogenesis and metabolic changes induced by a high-carbohydrate, low-fat meal in lean and overweight men.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18509688

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Squalene synthase inhibitors reduce plasma triglyceride through a low-density lipoprotein receptor-independent mechanism

1 reference

https://pubmed.ncbi.nlm.nih.gov/18509688

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isoform 1c of sterol regulatory element binding protein is less active than isoform 1a in livers of transgenic mice and in cultured cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/18509688

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The human fatty acid synthase gene and de novo lipogenesis are coordinately regulated in human adipose tissue

1 reference

https://pubmed.ncbi.nlm.nih.gov/18509688

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of the human PPARalpha promoter: identification of a functional nuclear receptor response element

1 reference

https://pubmed.ncbi.nlm.nih.gov/18509688

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Orphan nuclear receptors: from gene to function

1 reference

https://pubmed.ncbi.nlm.nih.gov/18509688

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Assignment of the membrane attachment, DNA binding, and transcriptional activation domains of sterol regulatory element-binding protein-1 (SREBP-1)

1 reference

https://pubmed.ncbi.nlm.nih.gov/18509688

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

YM-53601, a novel squalene synthase inhibitor, reduces plasma cholesterol and triglyceride levels in several animal species

1 reference

https://pubmed.ncbi.nlm.nih.gov/18509688

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Farnesol inhibits phosphatidylcholine biosynthesis in cultured cells by decreasing cholinephosphotransferase activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/18509688

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transcription factors acting on the promoter of the rat fatty acid synthase gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/18509688

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Farnesol is not the nonsterol regulator mediating degradation of HMG-CoA reductase in rat liver

1 reference

https://pubmed.ncbi.nlm.nih.gov/18509688

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Squalene synthase inhibitors suppress triglyceride biosynthesis through the farnesol pathway in rat hepatocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/18509688

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Volatile isoprenoid constituents of fruits, vegetables and herbs cumulatively suppress the proliferation of murine B16 melanoma and human HL-60 leukemia cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/18509688

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dual action of isoprenols from herbal medicines on both PPARgamma and PPARalpha in 3T3-L1 adipocytes and HepG2 hepatocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/18509688

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peroxisome proliferator-activated receptor-alpha agonist treatment in a transgenic model of type 2 diabetes reverses the lipotoxic state and improves glucose homeostasis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18509688

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mortality in vegetarians and nonvegetarians: detailed findings from a collaborative analysis of 5 prospective studies

1 reference

https://pubmed.ncbi.nlm.nih.gov/18509688

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modulation of hepatic and renal drug metabolizing enzyme activities in rats by subchronic administration of farnesol

1 reference

https://pubmed.ncbi.nlm.nih.gov/18509688

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of the Human PPARα Promoter: Identification of a Functional Nuclear Receptor Response Element

1 reference

https://pubmed.ncbi.nlm.nih.gov/18509688

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S11745-008-3192-3

1 reference

Europe PubMed Central

3 August 2017

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0 references

1 reference

Europe PubMed Central

3 August 2017

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