(Q44272184)

1 December 2017

title

Squalene synthase inhibitors suppress triglyceride biosynthesis through the farnesol pathway in rat hepatocytes (English)

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1 December 2017

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Hironobu Hiyoshi

1

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1 December 2017

Mamoru Yanagimachi

2

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1 December 2017

Masashi Ito

3

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1 December 2017

Nobuyuki Yasuda

4

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1 December 2017

Toshimi Okada

5

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1 December 2017

Hironori Ikuta

6

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1 December 2017

Daisuke Shinmyo

7

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1 December 2017

Keigo Tanaka

8

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1 December 2017

Nobuyuki Kurusu

9

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1 December 2017

Ichiro Yoshida

10

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1 December 2017

Shinya Abe

11

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1 December 2017

Takao Saeki

12

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1 December 2017

Hiroshi Tanaka

13

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1 December 2017

publication date

1 January 2003

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Journal of Lipid Research

1 December 2017

published in

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1 December 2017

volume

44

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1 December 2017

issue

1

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1 December 2017

page(s)

128-135

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Regulation of the mevalonate pathway

1 December 2017

cites work

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YM-53601, a novel squalene synthase inhibitor, reduces plasma cholesterol and triglyceride levels in several animal species

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Squalene synthase inhibitors reduce plasma triglyceride through a low-density lipoprotein receptor-independent mechanism

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Preferential induction of apoptosis of leukaemic cells by farnesol

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Farnesyl analogues inhibit vasoconstriction in animal and human arteries

21 January 2018

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Farnesol Inhibits L-type Ca2+Channels in Vascular Smooth Muscle Cells

21 January 2018

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Farnesol blocks the L-type Ca2+ channel by targeting the alpha 1C subunit

21 January 2018

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Regulation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase degradation by the nonsterol mevalonate metabolite farnesol in vivo

21 January 2018

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Farnesol as a regulator of HMG-CoA reductase degradation: characterization and role of farnesyl pyrophosphatase

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Identification of a nuclear receptor that is activated by farnesol metabolites

21 January 2018

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Farnesol stimulates differentiation in epidermal keratinocytes via PPARalpha

21 January 2018

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Increased lipogenic capacity of the islets of obese rats: a role in the pathogenesis of NIDDM.

21 January 2018

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S-carbocysteine-lysine salt monohydrate and cAMP cause non-additive activation of the cystic fibrosis transmembrane regulator channel in human respiratory epithelium

21 January 2018

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Prolonged inhibition of cholesterol synthesis by atorvastatin inhibits apo B-100 and triglyceride secretion from HepG2 cells

21 January 2018

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NK-104, a potent 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor, decreases apolipoprotein B-100 secretion from Hep G2 cells

21 January 2018

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Effects of NB-598, a potent squalene epoxidase inhibitor, on the apical membrane uptake of cholesterol and basolateral membrane secretion of lipids in Caco-2 cells

21 January 2018

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Fatty acid import into mitochondria

21 January 2018

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Sterol regulation of fatty acid synthase promoter. Coordinate feedback regulation of two major lipid pathways

21 January 2018

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Sterol regulation of acetyl coenzyme A carboxylase: a mechanism for coordinate control of cellular lipid

21 January 2018

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Identification of conserved cis-elements and transcription factors required for sterol-regulated transcription of stearoyl-CoA desaturase 1 and 2

21 January 2018

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Sterol regulatory element-binding protein-1 as a key transcription factor for nutritional induction of lipogenic enzyme genes

21 January 2018

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Regulation of fatty acid and cholesterol metabolism by the AMP-activated protein kinase

21 January 2018

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Bimodal activation of acetyl-CoA carboxylase by glutamate

21 January 2018

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Ubiquitin-mediated regulation of 3-hydroxy-3-methylglutaryl-CoA reductase

21 January 2018

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A highly conserved signal controls degradation of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase in eukaryotes

21 January 2018

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Degradation of 3-hydroxy-3-methylglutaryl-CoA reductase in endoplasmic reticulum membranes is accelerated as a result of increased susceptibility to proteolysis.

21 January 2018

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https://api.crossref.org/works/10.1194%2FJLR.M200316-JLR200

10.1194/JLR.M200316-JLR200

21 January 2018

Identifiers

DOI

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1 December 2017

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