(Q34657072)

3 August 2017

title

High-throughput decoding of drug targets and drug resistance mechanisms in African trypanosomes (English)

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3 August 2017

David Horn

1

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3 August 2017

publication date

8 April 2013

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3 August 2017

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3 August 2017

volume

141

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3 August 2017

issue

1

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3 August 2017

page(s)

77-82

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A molecular mechanism for eflornithine resistance in African trypanosomes

3 August 2017

cites work

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https://api.crossref.org/works/10.1017%2FS0031182013000243

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Selective cleavage of kinetoplast DNA minicircles promoted by antitrypanosomal drugs

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Genome-wide RNAi screens in bloodstream form trypanosomes identify drug transporters.

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High-throughput phenotyping using parallel sequencing of RNA interference targets in the African trypanosome

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Double-stranded RNA induces mRNA degradation in Trypanosoma brucei

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The Genome of the African Trypanosome Trypanosoma brucei

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Glycolysis modulates trypanosome glycoprotein expression as revealed by an RNAi library

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Genome-wide RNAi screens in African trypanosomes identify the nifurtimox activator NTR and the eflornithine transporter AAT6.

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Human African trypanosomiasis

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Polyamine metabolism: a potential therapeutic target in trypanosomes

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The Genome Sequence of Trypanosoma cruzi, Etiologic Agent of Chagas Disease

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Molecular mechanisms underlying the control of antigenic variation in African trypanosomes

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Network pharmacology: the next paradigm in drug discovery

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Aquaglyceroporin 2 controls susceptibility to melarsoprol and pentamidine in African trypanosomes

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7 January 2021

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SCYX-7158, an orally-active benzoxaborole for the treatment of stage 2 human African trypanosomiasis

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7 January 2021

Trypanosomal immune evasion, chronicity and transmission: an elegant balancing act

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7 January 2021

Nifurtimox activation by trypanosomal type I nitroreductases generates cytotoxic nitrile metabolites.

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7 January 2021

N-myristoyltransferase inhibitors as new leads to treat sleeping sickness

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7 January 2021

TDR Targets: a chemogenomics resource for neglected diseases

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7 January 2021

Address in Pathology, ON CHEMIOTHERAPY: Delivered before the Seventeenth International Congress of Medicine

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7 January 2021

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7 January 2021

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Identifiers

DOI

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3 August 2017

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