(Q21144510)

antiprotozoal

1 reference

benzamide

1 reference

boron compound

1 reference

24

Reto Brun

Reto

Brun

1 reference

17 August 2022

Marcel Kaiser

25

Marcel

Kaiser

1 reference

17 August 2022

Robert T Jacobs

1

Robert T

Jacobs

1 reference

17 August 2022

Bakela Nare

2

Bakela

Nare

1 reference

17 August 2022

Stephen A Wring

3

Stephen A

Wring

1 reference

17 August 2022

Matthew D Orr

4

Matthew D

Orr

1 reference

17 August 2022

Daitao Chen

5

Daitao

Chen

1 reference

17 August 2022

Jessica M Sligar

6

Jessica M

Sligar

1 reference

17 August 2022

Matthew X Jenks

7

Matthew X

Jenks

1 reference

17 August 2022

Robert A Noe

8

Robert A

Noe

1 reference

17 August 2022

Tana S Bowling

9

Tana S

Bowling

1 reference

17 August 2022

Luke T Mercer

10

Luke T

Mercer

1 reference

17 August 2022

Cindy Rewerts

11

Cindy

Rewerts

1 reference

17 August 2022

Eric Gaukel

12

Eric

Gaukel

1 reference

17 August 2022

Jennifer Owens

13

Jennifer

Owens

1 reference

17 August 2022

Robin Parham

14

Robin

Parham

1 reference

17 August 2022

Ryan Randolph

15

Ryan

Randolph

1 reference

17 August 2022

Beth Beaudet

16

Beth

Beaudet

1 reference

17 August 2022

Cyrus J Bacchi

17

Cyrus J

Bacchi

1 reference

17 August 2022

Nigel Yarlett

18

Nigel

Yarlett

1 reference

17 August 2022

Jacob J Plattner

19

Jacob J

Plattner

1 reference

17 August 2022

Yvonne Freund

20

Yvonne

Freund

1 reference

17 August 2022

Charles Ding

21

Charles

Ding

1 reference

17 August 2022

Tsutomu Akama

22

Tsutomu

Akama

1 reference

17 August 2022

Y-K Zhang

23

Y-K

Zhang

1 reference

17 August 2022

Ivan Scandale

26

Ivan

Scandale

1 reference

17 August 2022

Robert Don

27

Robert

Don

1 reference

PLoS Neglected Tropical Diseases

17 August 2022

language of work or name

English

0 references

publication date

June 2011

0 references

published in

0 references

volume

5

0 references

issue

6

0 references

page(s)

e1151

0 references

copyright license

Creative Commons Attribution 2.5 Generic

0 references

cites work

N-myristoyltransferase inhibitors as new leads to treat sleeping sickness

1 reference

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A mechanistic link between an inherited and an acquired cardiac arrhythmia: HERG encodes the IKr potassium channel

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3125149

NECT is next: implementing the new drug combination therapy for Trypanosoma brucei gambiense sleeping sickness

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3125149

Nifurtimox-eflornithine combination therapy for second-stage African Trypanosoma brucei gambiense trypanosomiasis: a multicentre, randomised, phase III, non-inferiority trial

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3125149

Nifurtimox plus Eflornithine for late-stage sleeping sickness in Uganda: a case series

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3125149

Properties of HERG channels stably expressed in HEK 293 cells studied at physiological temperature

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3125149

Discovery of novel benzoxaborole-based potent antitrypanosomal agents

19 March 2017

1 reference

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State of the art in African trypanosome drug discovery

12 September 2017

1 reference

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Discovery of novel orally bioavailable oxaborole 6-carboxamides that demonstrate cure in a murine model of late-stage central nervous system african trypanosomiasis

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3125149

Trypanocidal drugs: mechanisms, resistance and new targets

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3125149

NECT trial: more than a small victory over sleeping sickness

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3125149

The burden of human African trypanosomiasis

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3125149

Traversal of human and animal trypanosomes across the blood-brain barrier

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3125149

Eliminating human African trypanosomiasis: where do we stand and what comes next?

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3125149

Human African trypanosomiasis: pharmacological re-engagement with a neglected disease.

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3125149

Semimechanistic pharmacokinetic/pharmacodynamic model for assessment of activity of antibacterial agents from time-kill curve experiments

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3125149

Chemotherapy of trypanosomiases and leishmaniasis

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3125149

Issues in pharmacokinetics and pharmacodynamics of anti-infective agents: kill curves versus MIC

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3125149

Therapy of human African trypanosomiasis: current situation

12 September 2017

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3125149

12 September 2017

https://api.crossref.org/works/10.1371%2FJOURNAL.PNTD.0001151

A comparative review of the pharmacokinetics of boric acid in rodents and humans

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3125149

Antitrypanosomal activity of a new triazine derivative, SIPI 1029, In vitro and in model infections

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3125149

The Alamar Blue assay to determine drug sensitivity of African trypanosomes (T.b. rhodesiense and T.b. gambiense) in vitro

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3125149

In vivo trypanocidal activities of new S-adenosylmethionine decarboxylase inhibitors

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3125149

Cultivation in a semi-defined medium of animal infective forms of Trypanosoma brucei, T. equiperdum, T. evansi, T. rhodesiense and T. gambiense

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3125149

Methods for detecting carcinogens and mutagens with the Salmonella/mammalian-microsome mutagenicity test

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3125149

Biopharmaceutics classification system: validation and learnings of an in vitro permeability assay

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3125149

In vitro absorption and secretory quotients: practical criteria derived from a study of 331 compounds to assess for the impact of P-glycoprotein-mediated efflux on drug candidates.

27 September 2017

1 reference

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Blockage of the HERG human cardiac K+ channel by the gastrointestinal prokinetic agent cisapride.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3125149

Human drug metabolism in vitro.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3125149

Rational use of in vitro P-glycoprotein assays in drug discovery

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3125149

Effects of the ornithine decarboxylase inhibitors DL-alpha-difluoromethylornithine and alpha-monofluoromethyldehydroornithine methyl ester alone and in combination with suramin against Trypanosoma brucei brucei central nervous system models.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3125149

Continuous cultivation of Trypanosoma brucei blood stream forms in a medium containing a low concentration of serum protein without feeder cell layers

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3125149

Nifurtimox-eflornithine combination therapy for second-stage Trypanosoma brucei gambiense sleeping sickness: a randomized clinical trial in Congo

30 May 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PNTD.0001151

Optimizing classification of drug-drug interaction potential for CYP450 isoenzyme inhibition assays in early drug discovery.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PNTD.0001151

Steady-state brain concentrations of antihistamines in rats: interplay of membrane permeability, P-glycoprotein efflux and plasma protein binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PNTD.0001151

Blood boron concentrations in pregnant rats fed boric acid throughout gestation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PNTD.0001151

Human African trypanosomiasis (sleeping sickness): epidemiological update

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3125149

Relapsed parasitaemia following chemotherapy of chronic T. brucei infections in mice and its relation to cerebral trypanosomes.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3125149

Novel experimental parameters to quantify the modulation of absorptive and secretory transport of compounds by P-glycoprotein in cell culture models of intestinal epithelium

29 November 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/21738803

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PNTD.0001151

1 reference

1 reference

1 reference

1 reference