(Q34657321)

3 August 2017

A phenotypic screening assay for modulators of huntingtin-induced transcriptional dysregulation (English)

1 reference

transcriptional dysregulation

3 August 2017

1 reference

Giulia Lazzeroni

1

1 reference

3 August 2017

Tiziana Benicchi

2

1 reference

3 August 2017

Freddy Heitz

3

1 reference

3 August 2017

Letizia Magnoni

4

1 reference

3 August 2017

Daniela Diamanti

5

1 reference

3 August 2017

Lara Rossini

6

1 reference

3 August 2017

Luisa Massai

7

1 reference

3 August 2017

Cesare Federico

8

1 reference

3 August 2017

Wolfgang Fecke

9

1 reference

3 August 2017

Andrea Caricasole

10

1 reference

3 August 2017

Salvatore La Rosa

11

1 reference

3 August 2017

Valentina Porcari

12

1 reference

3 August 2017

5 April 2013

1 reference

Journal of Biomolecular Screening

3 August 2017

1 reference

3 August 2017

18

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3 August 2017

9

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3 August 2017

984-996

1 reference

Huntington's disease: progress and potential in the field

3 August 2017

1 reference

https://api.crossref.org/works/10.1177%2F1087057113484802

The relationship between trinucleotide (CAG) repeat length and clinical features of Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057113484802

Protein aggregates in Huntington's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057113484802

Wild-type huntingtin ameliorates striatal neuronal atrophy but does not prevent other abnormalities in the YAC128 mouse model of Huntington disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057113484802

Transcription meets metabolism in neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057113484802

Huntingtin interacting proteins are genetic modifiers of neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057113484802

Decreased expression of striatal signaling genes in a mouse model of Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057113484802

Mutant Huntingtin reduces HSP70 expression through the sequestration of NF-Y transcription factor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057113484802

p53 mediates cellular dysfunction and behavioral abnormalities in Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057113484802

Sp1 and TAFII130 transcriptional activity disrupted in early Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057113484802

The role of REST in transcriptional and epigenetic dysregulation in Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057113484802

Transcriptional repression of PGC-1alpha by mutant huntingtin leads to mitochondrial dysfunction and neurodegeneration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057113484802

Inhibition of specific HDACs and sirtuins suppresses pathogenesis in a Drosophila model of Huntington's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057113484802

Neuroprotective role of Sirt1 in mammalian models of Huntington's disease through activation of multiple Sirt1 targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057113484802

Polyglutamine expansions cause decreased CRE-mediated transcription and early gene expression changes prior to cell death in an inducible cell model of Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057113484802

Decreased cAMP response element-mediated transcription: an early event in exon 1 and full-length cell models of Huntington's disease that contributes to polyglutamine pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057113484802

CREB: a multifaceted regulator of neuronal plasticity and protection

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057113484802

Depletion of CBP is directly linked with cellular toxicity caused by mutant huntingtin

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057113484802

Mutant huntingtin represses CBP, but not p300, by binding and protein degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057113484802

Small molecule drug discovery for Huntington's Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057113484802

Drug screening for Huntington's disease and other neurodegenerative disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057113484802

A screen for enhancers of clearance identifies huntingtin as a heat shock protein 90 (Hsp90) client protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057113484802

Discovery of a novel small-molecule targeting selective clearance of mutant huntingtin fragments.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057113484802

A Rapid Cellular FRET Assay of Polyglutamine Aggregation Identifies a Novel Inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057113484802

A cell-based screen for drugs to treat Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057113484802

Compounds blocking mutant huntingtin toxicity identified using a Huntington's disease neuronal cell model

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057113484802

Selective inhibitors of death in mutant huntingtin cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057113484802

Long-term memory deficits in Huntington's disease are associated with reduced CBP histone acetylase activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057113484802

A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057113484802

Y-27632 improves rotarod performance and reduces huntingtin levels in R6/2 mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057113484802

Diverse roles of Rho family GTPases in neuronal development, survival, and death

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1087057113484802

21 January 2018

Identifiers

DOI

10.1177/1087057113484802

1 reference

3 August 2017

1 reference