(Q34658008)

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Formation of hydrogen peroxide and hydroxyl radicals from A(beta) and alpha-synuclein as a possible mechanism of cell death in Alzheimer's disease and Parkinson's disease

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scholarly article

1 reference

Europe PubMed Central

3 August 2017

1 reference

Europe PubMed Central

Formation of hydrogen peroxide and hydroxyl radicals from A(beta) and alpha-synuclein as a possible mechanism of cell death in Alzheimer's disease and Parkinson's disease (English)

1 reference

Europe PubMed Central

3 August 2017

Parkinson's disease

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inferred from title

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Alzheimer's disease

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object named as

David Allsop

4

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author name string

Brian J Tabner

1

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Europe PubMed Central

3 August 2017

Stuart Turnbull

2

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Europe PubMed Central

3 August 2017

Omar M A El-Agnaf

3

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Europe PubMed Central

3 August 2017

publication date

1 June 2002

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Europe PubMed Central

3 August 2017

Free Radical Biology and Medicine

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Europe PubMed Central

3 August 2017

32

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Europe PubMed Central

3 August 2017

1076-1083

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Europe PubMed Central

3 August 2017

11

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Europe PubMed Central

3 August 2017

Amyloid deposition as the central event in the aetiology of Alzheimer's disease

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https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900801-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Production of reactive oxygen species from aggregating proteins implicated in Alzheimer's disease, Parkinson's disease and other neurodegenerative diseases

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900801-8

7 January 2021

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Protein precipitation: a common etiology in neurodegenerative disorders?

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900801-8

7 January 2021

based on heuristic

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The role of oxidative stress in the toxicity induced by amyloid beta-peptide in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900801-8

7 January 2021

based on heuristic

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Protofibrils, the unifying toxic molecule of neurodegenerative disorders?

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900801-8

7 January 2021

based on heuristic

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A model for beta-amyloid aggregation and neurotoxicity based on free radical generation by the peptide: relevance to Alzheimer disease

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900801-8

7 January 2021

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The Aβ Peptide of Alzheimer's Disease Directly Produces Hydrogen Peroxide through Metal Ion Reduction†

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900801-8

7 January 2021

based on heuristic

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Cu(II) potentiation of alzheimer abeta neurotoxicity. Correlation with cell-free hydrogen peroxide production and metal reduction.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900801-8

7 January 2021

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Metals and neuroscience.

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https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900801-8

7 January 2021

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Methionine residue 35 is important in amyloid beta-peptide-associated free radical oxidative stress.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900801-8

7 January 2021

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Review: Alzheimer's amyloid beta-peptide-associated free radical oxidative stress and neurotoxicity

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https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900801-8

7 January 2021

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Different mechanisms of oxidative stress and neurotoxicity for Alzheimer's A beta(1--42) and A beta(25--35).

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900801-8

7 January 2021

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The relationship between Abeta-associated free radical generation and Abeta fibril formation revealed by negative stain electron microscopy and thioflavine-T fluorometric assay

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900801-8

7 January 2021

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The relationship between the aggregational state of the amyloid-beta peptides and free radical generation by the peptides

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900801-8

7 January 2021

based on heuristic

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New evidence that the Alzheimer beta-amyloid peptide does not spontaneously form free radicals: an ESR study using a series of spin-traps.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900801-8

7 January 2021

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Copper and zinc binding modulates the aggregation and neurotoxic properties of the prion peptide PrP106-126.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900801-8

7 January 2021

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alpha-Synuclein implicated in Parkinson's disease catalyses the formation of hydrogen peroxide in vitro.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900801-8

7 January 2021

based on heuristic

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Cautionary note for DMPO spin trapping in the presence of iron ion

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900801-8

7 January 2021

based on heuristic

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A de novo designed helix-turn-helix peptide forms nontoxic amyloid fibrils.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900801-8

7 January 2021

based on heuristic

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Oxidative stress and the pathogenesis of Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900801-8

7 January 2021

based on heuristic

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Parkinson's disease--redox mechanisms

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900801-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Molecular cloning of cDNA encoding an unrecognized component of amyloid in Alzheimer disease

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900801-8

7 January 2021

based on heuristic

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Identification of two distinct synucleins from human brain

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900801-8

7 January 2021

based on heuristic

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The precursor protein of non-A beta component of Alzheimer's disease amyloid is a presynaptic protein of the central nervous system

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900801-8

7 January 2021

based on heuristic

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Mutation in the alpha-synuclein gene identified in families with Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900801-8

7 January 2021

based on heuristic

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Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900801-8

7 January 2021

based on heuristic

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Alpha-synuclein in Lewy bodies

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900801-8

7 January 2021

based on heuristic

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alpha-Synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with lewy bodies

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900801-8

7 January 2021

based on heuristic

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Neuropathology in mice expressing human alpha-synuclein

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900801-8

7 January 2021

based on heuristic

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Dopaminergic loss and inclusion body formation in alpha-synuclein mice: implications for neurodegenerative disorders

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900801-8

7 January 2021

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Aggregates from mutant and wild-type alpha-synuclein proteins and NAC peptide induce apoptotic cell death in human neuroblastoma cells by formation of beta-sheet and amyloid-like filaments

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900801-8

7 January 2021

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Induction of neuronal death by α-synuclein

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900801-8

7 January 2021

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The oligomerization of amyloid beta-protein begins intracellularly in cells derived from human brain

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900801-8

7 January 2021

based on heuristic

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Oxidation of methionyl residues in proteins: tools, targets, and reversal

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900801-8

7 January 2021

based on heuristic

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Generation and propagation of radical reactions on proteins.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900801-8

7 January 2021

based on heuristic

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Radical-induced chain oxidation of proteins and its inhibition by chain-breaking antioxidants

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900801-8

7 January 2021

based on heuristic

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Alzheimer's disease amyloid-beta binds copper and zinc to generate an allosterically ordered membrane-penetrating structure containing superoxide dismutase-like subunits

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900801-8

7 January 2021

based on heuristic

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XAFS study of the high-affinity copper-binding site of human PrP(91-231) and its low-resolution structure in solution

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900801-8

7 January 2021

based on heuristic

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Production of superoxide from hemoglobin-bound oxygen under hypoxic conditions

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900801-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Mechanisms by which metals promote events connected to neurodegenerative diseases

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900801-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Oxidative stress hypothesis in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900801-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Oxidative stress and neurodegenerative disorders

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900801-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1016/S0891-5849(02)00801-8

1 reference

Europe PubMed Central

3 August 2017

1 reference

Europe PubMed Central

3 August 2017

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