(Q34659023)

3 August 2017

1 reference

title

Design of functional metalloproteins (English)

1 reference

3 August 2017

Yi Lu

1

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author name string

Natasha Yeung

series ordinal

2

1 reference

3 August 2017

Nathan Sieracki

series ordinal

3

1 reference

3 August 2017

Nicholas M Marshall

series ordinal

4

1 reference

3 August 2017

language of work or name

English

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publication date

1 August 2009

1 reference

3 August 2017

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3 August 2017

460

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3 August 2017

7257

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3 August 2017

855-862

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https://scigraph.springernature.com/pub.10.1038/nature08304

3 August 2017

0 references

cites work

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Harnessing natures ability to control metal ion coordination geometry using de novo designed peptides.

7 July 2018

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The correlation of 113Cd NMR and 111mCd PAC spectroscopies provides a powerful approach for the characterization of the structure of Cd(II)-substituted Zn(II) proteins

7 July 2018

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Using diastereopeptides to control metal ion coordination in proteins

7 July 2018

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One heme, diverse functions: using biosynthetic myoglobin models to gain insights into heme-copper oxidases and nitric oxide reductases

7 July 2018

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Designed metal-binding sites in biomolecular and bioinorganic interactions.

7 July 2018

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Protein scaffold of a designed metalloenzyme enhances the chemoselectivity in sulfoxidation of thioanisole

7 July 2018

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X-ray structure and designed evolution of an artificial transfer hydrogenase

7 July 2018

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Controlling Protein−Protein Interactions through Metal Coordination: Assembly of a 16-Helix Bundle Protein

7 July 2018

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Peroxidase activity of de novo heme proteins immobilized on electrodes

7 July 2018

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De novo design of a single-chain diphenylporphyrin metalloprotein

7 July 2018

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Identifying important structural characteristics of arsenic resistance proteins by using designed three-stranded coiled coils

7 July 2018

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Detection of heme oxygenase activity in a library of four-helix bundle proteins: towards the de novo synthesis of functional heme proteins

7 July 2018

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Crystal structure and peroxidase activity of myoglobin reconstituted with iron porphycene

7 July 2018

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Metalloprotein and metallo-DNA/RNAzyme design: current approaches, success measures, and future challenges

7 July 2018

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Catalytic reduction of NO to N2O by a designed heme copper center in myoglobin: implications for the role of metal ions

7 July 2018

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Protein stability promotes evolvability

7 July 2018

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Role of heme types in heme-copper oxidases: effects of replacing a heme b with a heme o mimic in an engineered heme-copper center in myoglobin

7 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2770889

Design and engineering of metalloproteins containing unnatural amino acids or non-native metal-containing cofactors

7 July 2018

1 reference

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Probing metal-protein interactions using a de novo design approach

7 July 2018

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Computational de novo design and characterization of a four-helix bundle protein that selectively binds a nonbiological cofactor

7 July 2018

1 reference

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De novo design of catalytic proteins

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2770889

Size-selective olefin hydrogenation by a Pd nanocluster provided in an apo-ferritin cage

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2770889

The HP-1 maquette: from an apoprotein structure to a structured hemoprotein designed to promote redox-coupled proton exchange

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2770889

A catalysis-based selection for peroxidase antibodies with increased activity

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2770889

7 July 2018

Heme protein assemblies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2770889

Designing redox metalloproteins from bottom-up and top-down perspectives

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2770889

The role of copper and protons in heme-copper oxidases: kinetic study of an engineered heme-copper center in myoglobin

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2770889

Semisynthesis of proteins by expressed protein ligation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2770889

Hg(II) binding to a weakly associated coiled coil nucleates an encoded metalloprotein fold: a kinetic analysis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2770889

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2770889

New functionalization of myoglobin by chemical modification of heme-propionates

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2770889

Generation of new enzymes via covalent modification of existing proteins

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2770889

Engineering novel metalloproteins: design of metal-binding sites into native protein scaffolds.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2770889

Statistical theory for protein combinatorial libraries. Packing interactions, backbone flexibility, and the sequence variability of a main-chain structure.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2770889

De novo design and structural characterization of proteins and metalloproteins

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2770889

Retrostructural analysis of metalloproteins: application to the design of a minimal model for diiron proteins

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2770889

Structural basis of electron transfer modulation in the purple CuA center

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2770889

Enhanced rate of intramolecular electron transfer in an engineered purple CuA azurin

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2770889

Structural characterization of two synthetic catalysts based on adipocyte lipid-binding protein

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2770889

Construction of a novel redox protein by rational design: conversion of a disulfide bridge into a mononuclear iron-sulfur center.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2770889

Concept and early development of solid-phase peptide synthesis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2770889

Construction and characterization of an azurin analog for the purple copper site in cytochrome c oxidase

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2770889

Energised (entatic) states of groups and of secondary structures in proteins and metalloproteins

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2770889

Synthesis of proteins by native chemical ligation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2770889

Grafting of a high-affinity Zn(II)-binding site on the beta-barrel of retinol-binding protein results in enhanced folding stability and enables simplified purification

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2770889

Depletion and replacement of protein metal ligands

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2770889

Scorpion toxins as natural scaffolds for protein engineering

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2770889

A general method for site-specific incorporation of unnatural amino acids into proteins.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2770889

Engineering a uranyl-specific binding protein from NikR.

7 July 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE08304

Protein design provides lead(II) ion biosensors for imaging molecular fluxes around red blood cells

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2770889

Biosynthesis of a site-specific DNA cleaving protein

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2770889

Oxygen reactivity of the biferrous site in the de novo designed four helix bundle peptide DFsc: nature of the "intermediate" and reaction mechanism

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2770889

Ratiometric detection of Zn(II) using chelating fluorescent protein chimeras.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2770889

Enantioselective proteins: selection, binding studies and molecular modeling of antibodies with affinity towards hydrophobic BINOL derivatives

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2770889

Engineered alkane-hydroxylating cytochrome P450(BM3) exhibiting nativelike catalytic properties

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2770889

Metal-ion-dependent GFP emission in vivo by combining a circularly permutated green fluorescent protein with an engineered metal-ion-binding coiled-coil.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2770889

Design and evolution of new catalytic activity with an existing protein scaffold

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2770889

Biomimetic synthesis of a H2 catalyst using a protein cage architecture

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2770889

De novo design of a redox-active minimal rubredoxin mimic

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2770889

Metal-induced folding of a designed metalloprotein

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2770889

Artificial metalloenzymes for enantioselective catalysis based on biotin-avidin.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2770889

A site-selective dual anchoring strategy for artificial metalloprotein design

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2770889

Comparison of cysteine and penicillamine ligands in a Co(II) maquette.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2770889

Crystal structures of artificial metalloproteins: tight binding of FeIII(Schiff-Base) by mutation of Ala71 to Gly in apo-myoglobin

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2770889

Binding of Cu(II) or Zn(II) in a de novo designed triple-stranded alpha-helical coiled-coil toward a prototype for a metalloenzyme.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2770889

Synthesis of a novel histidine analogue and its efficient incorporation into a protein in vivo.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2770889

An engineered CuA Amicyanin capable of intermolecular electron transfer reactions.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2770889

Probing the role of axial methionine in the blue copper center of azurin with unnatural amino acids

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2770889

Rational design of a calcium-binding protein

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2770889

Reductive activation of dioxygen by a myoglobin reconstituted with a flavohemin

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2770889

Comparison of the binding of cadmium(II), mercury(II), and arsenic(III) to the de novo designed peptides TRI L12C and TRI L16C.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2770889

Nonnatural amino acid ligands in heme protein design.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2770889

An engineered azurin variant containing a selenocysteine copper ligand

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2770889

Computer search algorithms in protein modification and design.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2770889

Introduction of a CuA site into the blue copper protein amicyanin from Thiobacillus versutus.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2770889

Enhanced fluorescence resonance energy transfer between spectral variants of green fluorescent protein through zinc-site engineering

26 October 2018

1 reference

12 December 2020

Artificial transfer hydrogenases based on the biotin-(strept)avidin technology: fine tuning the selectivity by saturation mutagenesis of the host protein

1 reference

12 December 2020

Computational de novo design, and characterization of an A(2)B(2) diiron protein

1 reference

12 December 2020

Design and synthesis of multi-haem proteins

1 reference

12 December 2020

Characterization of metal binding by a designed protein: single ligand substitutions at a tetrahedral Cys2His2 site

1 reference

12 December 2020

Using nonnatural amino acids to control metal-coordination number in three-stranded coiled coils

1 reference

12 December 2020

Femtomolar Zn(II) affinity in a peptide-based ligand designed to model thiolate-rich metalloprotein active sites

1 reference

12 December 2020

Metal-assembled modular proteins: toward functional protein design

1 reference

12 December 2020

Preparation of artificial metalloenzymes by insertion of chromium(III) Schiff base complexes into apomyoglobin mutants

1 reference

12 December 2020

Construction and characterization of a manganese-binding site in cytochrome c peroxidase: towards a novel manganese peroxidase

1 reference

12 December 2020

Linear free-energy analysis of mercury(II) and cadmium(II) binding to three-stranded coiled coils

1 reference

https://api.crossref.org/works/10.1038%2FNATURE08304

7 January 2021

From Myoglobin to Heme-Copper Oxidase: Design and Engineering of a CuBCenter into Sperm Whale Myoglobin

1 reference

https://api.crossref.org/works/10.1038%2FNATURE08304

7 January 2021

Conversion of a protein to a homogeneous asymmetric hydrogenation catalyst by site-specific modification with a diphosphinerhodium(I) moiety

1 reference

https://api.crossref.org/works/10.1038%2FNATURE08304

7 January 2021

A Semisynthetic Metalloenzyme Based on a Protein Cavity That Catalyzes the Enantioselective Hydrolysis of Ester and Amide Substrates

1 reference

https://api.crossref.org/works/10.1038%2FNATURE08304

7 January 2021

Identifiers

DOI

10.1038/NATURE08304

1 reference

3 August 2017

1 reference

3 August 2017

1 reference