(Q34659418)

3 August 2017

1 reference

title

Phosphoinositide-binding domains: Functional units for temporal and spatial regulation of intracellular signalling (English)

1 reference

3 August 2017

Toshiki Itoh

1

1 reference

3 August 2017

Tadaomi Takenawa

series ordinal

2

1 reference

3 August 2017

publication date

1 September 2002

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3 August 2017

number of pages

11

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inferred from page(s)

published in

Cellular Signalling

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3 August 2017

volume

14

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3 August 2017

issue

9

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3 August 2017

page(s)

733-743

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Phosphoinositide lipids as signaling molecules: common themes for signal transduction, cytoskeletal regulation, and membrane trafficking

3 August 2017

cites work

1 reference

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7 January 2021

Signaling and subcellular targeting by membrane-binding domains

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7 January 2021

Specific interaction between phosphatidylinositol 4,5-bisphosphate and profilactin

1 reference

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7 January 2021

Modulation of gelsolin function by phosphatidylinositol 4,5-bisphosphate

1 reference

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7 January 2021

Requirement of phosphatidylinositol 4,5-bisphosphate for alpha-actinin function

1 reference

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7 January 2021

gCap39, a calcium ion- and polyphosphoinositide-regulated actin capping protein

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2802%2900028-1

7 January 2021

Controlling cytoskeleton structure by phosphoinositide-protein interactions: phosphoinositide binding protein domains and effects of lipid packing.

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2802%2900028-1

7 January 2021

Pleckstrin homology domains bind to phosphatidylinositol-4,5-bisphosphate.

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2802%2900028-1

7 January 2021

Direct regulation of the Akt proto-oncogene product by phosphatidylinositol-3,4-bisphosphate

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2802%2900028-1

7 January 2021

A specific product of phosphatidylinositol 3-kinase directly activates the protein kinase Akt through its pleckstrin homology domain.

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2802%2900028-1

7 January 2021

Dual role of phosphatidylinositol-3,4,5-trisphosphate in the activation of protein kinase B

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2802%2900028-1

7 January 2021

3-Phosphoinositide-dependent protein kinase-1 (PDK1): structural and functional homology with the Drosophila DSTPK61 kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2802%2900028-1

7 January 2021

Protein kinase B kinases that mediate phosphatidylinositol 3,4,5-trisphosphate-dependent activation of protein kinase B

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2802%2900028-1

7 January 2021

Signaling by phosphoinositide-3,4,5-trisphosphate through proteins containing pleckstrin and Sec7 homology domains

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2802%2900028-1

7 January 2021

A functional PtdIns(3)P-binding motif

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2802%2900028-1

7 January 2021

FYVE fingers bind PtdIns(3)P

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2802%2900028-1

7 January 2021

In vitro binding and phosphorylation of insulin receptor substrate 1 by the insulin receptor. Role of interactions mediated by the phosphotyrosine-binding domain and the pleckstrin-homology domain.

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2802%2900028-1

7 January 2021

PtdIns(3)P regulates the neutrophil oxidase complex by binding to the PX domain of p40phox

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2802%2900028-1

7 January 2021

The PX domains of p47phox and p40phox bind to lipid products of PI(3)K

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2802%2900028-1

7 January 2021

Phox homology domains specifically bind phosphatidylinositol phosphates.

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2802%2900028-1

7 January 2021

Role of the ENTH domain in phosphatidylinositol-4,5-bisphosphate binding and endocytosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2802%2900028-1

7 January 2021

Simultaneous binding of PtdIns(4,5)P2 and clathrin by AP180 in the nucleation of clathrin lattices on membranes

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2802%2900028-1

7 January 2021

Phosphoinositide kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2802%2900028-1

7 January 2021

Phospholipid-binding protein domains

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2802%2900028-1

7 January 2021

Signal-dependent membrane targeting by pleckstrin homology (PH) domains

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2802%2900028-1

7 January 2021

Solution structure of a pleckstrin-homology domain

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2802%2900028-1

7 January 2021

The pleckstrin homology domain of phospholipase C-delta 1 binds with high affinity to phosphatidylinositol 4,5-bisphosphate in bilayer membranes.

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2802%2900028-1

7 January 2021

Specific and high-affinity binding of inositol phosphates to an isolated pleckstrin homology domain

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2802%2900028-1

7 January 2021

Identification of the Binding Site for Acidic Phospholipids on the PH Domain of Dynamin: Implications for Stimulation of GTPase Activity

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2802%2900028-1

7 January 2021

High affinity binding of the pleckstrin homology domain of mSos1 to phosphatidylinositol (4,5)-bisphosphate

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2802%2900028-1

7 January 2021

The role of the PH domain in the signal-dependent membrane targeting of Sos.

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2802%2900028-1

7 January 2021

A comparative analysis of the phosphoinositide binding specificity of pleckstrin homology domains

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2802%2900028-1

7 January 2021

Specificity and promiscuity in phosphoinositide binding by pleckstrin homology domains

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2802%2900028-1

7 January 2021

The Pleckstrin Homology Domains of Dynamin Isoforms Require Oligomerization for High Affinity Phosphoinositide Binding

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2802%2900028-1

7 January 2021

EEA1, an early endosome-associated protein. EEA1 is a conserved alpha-helical peripheral membrane protein flanked by cysteine "fingers" and contains a calmodulin-binding IQ motif

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2802%2900028-1

7 January 2021

Endosomal localization of the autoantigen EEA1 is mediated by a zinc-binding FYVE finger

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2802%2900028-1

7 January 2021

Identification of an early endosomal protein regulated by phosphatidylinositol 3-kinase.

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2802%2900028-1

7 January 2021

Phosphatidylinositol(3)-phosphate signaling mediated by specific binding to RING FYVE domains

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2802%2900028-1

7 January 2021

Phosphatidylinositol 3-kinase encoded by yeast VPS34 gene essential for protein sorting

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2802%2900028-1

7 January 2021

EEA1 links PI(3)K function to Rab5 regulation of endosome fusion

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2802%2900028-1

7 January 2021

Oligomeric complexes link Rab5 effectors with NSF and drive membrane fusion via interactions between EEA1 and syntaxin 13

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2802%2900028-1

7 January 2021

Growth factor-induced tyrosine phosphorylation of Hrs, a novel 115-kilodalton protein with a structurally conserved putative zinc finger domain

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2802%2900028-1

7 January 2021

VPS27 controls vacuolar and endocytic traffic through a prevacuolar compartment in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2802%2900028-1

7 January 2021

Hrs recruits clathrin to early endosomes

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2802%2900028-1

7 January 2021

Endosomal localization and receptor dynamics determine tyrosine phosphorylation of hepatocyte growth factor-regulated tyrosine kinase substrate

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2802%2900028-1

7 January 2021

Hrs, a FYVE finger protein localized to early endosomes, is implicated in vesicular traffic and required for ventral folding morphogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2802%2900028-1

7 January 2021

Early endosomal localization of hrs requires a sequence within the proline- and glutamine-rich region but not the FYVE finger

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2802%2900028-1

7 January 2021

Localization of phosphatidylinositol 3-phosphate in yeast and mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2802%2900028-1

7 January 2021

Novel PI(4)P 5-kinase homologue, Fab1p, essential for normal vacuole function and morphology in yeast

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2802%2900028-1

7 January 2021

Fab1p PtdIns(3)P 5-kinase function essential for protein sorting in the multivesicular body

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2802%2900028-1

7 January 2021

The stress-activated phosphatidylinositol 3-phosphate 5-kinase Fab1p is essential for vacuole function in S. cerevisiae

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2802%2900028-1

7 January 2021

Fab1p is essential for PtdIns(3)P 5-kinase activity and the maintenance of vacuolar size and membrane homeostasis

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2802%2900028-1

7 January 2021

Mammalian cell morphology and endocytic membrane homeostasis require enzymatically active phosphoinositide 5-kinase PIKfyve

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2802%2900028-1

7 January 2021

Cloning, characterization, and expression of a novel Zn2+-binding FYVE finger-containing phosphoinositide kinase in insulin-sensitive cells

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2802%2900028-1

7 January 2021

SARA, a FYVE domain protein that recruits Smad2 to the TGFbeta receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2802%2900028-1

7 January 2021

Faciogenital dysplasia protein (FGD1) and Vav, two related proteins required for normal embryonic development, are upstream regulators of Rho GTPases

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2802%2900028-1

7 January 2021

Isolation and characterization of the faciogenital dysplasia (Aarskog-Scott syndrome) gene: a putative Rho/Rac guanine nucleotide exchange factor

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2802%2900028-1

7 January 2021

Two actions of frabin: direct activation of Cdc42 and indirect activation of Rac.

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2802%2900028-1

7 January 2021

LZ-FYVE: a novel developmental stage-specific leucine zipper, FYVE-finger protein

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2802%2900028-1

7 January 2021

Nuclear inositides: inconsistent consistencies

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2802%2900028-1

7 January 2021

Novel domains in NADPH oxidase subunits, sorting nexins, and PtdIns 3-kinases: binding partners of SH3 domains?

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2802%2900028-1

7 January 2021

Wortmannin is a potent phosphatidylinositol 3-kinase inhibitor: the role of phosphatidylinositol 3,4,5-trisphosphate in neutrophil responses.

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2802%2900028-1

7 January 2021

Identification of CISK, a new member of the SGK kinase family that promotes IL-3-dependent survival

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2802%2900028-1

7 January 2021

Phox domain interaction with PtdIns(3)P targets the Vam7 t-SNARE to vacuole membranes.

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2802%2900028-1

7 January 2021

SNX3 regulates endosomal function through its PX-domain-mediated interaction with PtdIns(3)P

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2802%2900028-1

7 January 2021

Central role for G protein-coupled phosphoinositide 3-kinase gamma in inflammation.

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2802%2900028-1

7 January 2021

Enhanced degradation of EGF receptors by a sorting nexin, SNX1

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2802%2900028-1

7 January 2021

Identification of a family of sorting nexin molecules and characterization of their association with receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2802%2900028-1

7 January 2021

Regulation of cytokine-independent survival kinase (CISK) by the Phox homology domain and phosphoinositides

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2802%2900028-1

7 January 2021

All phox homology (PX) domains from Saccharomyces cerevisiae specifically recognize phosphatidylinositol 3-phosphate.

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2802%2900028-1

7 January 2021

Identification of a novel domain shared by putative components of the endocytic and cytoskeletal machinery

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2802%2900028-1

7 January 2021

Developmental selection of var gene expression in Plasmodium falciparum

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2802%2900028-1

7 January 2021

Yeast epsins contain an essential N-terminal ENTH domain, bind clathrin and are required for endocytosis

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2802%2900028-1

7 January 2021

Regulation of AP-3 function by inositides. Identification of phosphatidylinositol 3,4,5-trisphosphate as a potent ligand

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2802%2900028-1

7 January 2021

Cloning, expression analysis, and chromosomal localization of HIP1R, an isolog of huntingtin interacting protein (HIP1).

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2802%2900028-1

7 January 2021

An actin-binding protein of the Sla2/Huntingtin interacting protein 1 family is a novel component of clathrin-coated pits and vesicles

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2802%2900028-1

7 January 2021

The actin-binding protein Hip1R associates with clathrin during early stages of endocytosis and promotes clathrin assembly in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2802%2900028-1

7 January 2021

End4p/Sla2p interacts with actin-associated proteins for endocytosis in Saccharomyces cerevisiae.

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2802%2900028-1

7 January 2021

Dynamin and its role in membrane fission

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2802%2900028-1

7 January 2021

Dominant-negative inhibition of receptor-mediated endocytosis by a dynamin-1 mutant with a defective pleckstrin homology domain.

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2802%2900028-1

7 January 2021

Essential role of the dynamin pleckstrin homology domain in receptor-mediated endocytosis

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2802%2900028-1

7 January 2021

A functional phosphatidylinositol 3,4,5-trisphosphate/phosphoinositide binding domain in the clathrin adaptor AP-2 alpha subunit. Implications for the endocytic pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2802%2900028-1

7 January 2021

Phosphoinositide-AP-2 interactions required for targeting to plasma membrane clathrin-coated pits

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2802%2900028-1

7 January 2021

Structure of the pleckstrin homology domain from beta-spectrin.

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2802%2900028-1

7 January 2021

Three-dimensional solution structure of the pleckstrin homology domain from dynamin

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2802%2900028-1

7 January 2021

Crystal structure at 2.2 A resolution of the pleckstrin homology domain from human dynamin

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2802%2900028-1

7 January 2021

Crystal structure of the pleckstrin homology domain from dynamin

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2802%2900028-1

7 January 2021

Solution structure of pleckstrin homology domain of dynamin by heteronuclear NMR spectroscopy

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2802%2900028-1

7 January 2021

Structure of the binding site for inositol phosphates in a PH domain

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2802%2900028-1

7 January 2021

Structure of the high affinity complex of inositol trisphosphate with a phospholipase C pleckstrin homology domain

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2802%2900028-1

7 January 2021

Crystal structure of a phosphatidylinositol 3-phosphate-specific membrane-targeting motif, the FYVE domain of Vps27p

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2802%2900028-1

7 January 2021

Phosphatidylinositol 3-Phosphate Recognition by the FYVE Domain

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2802%2900028-1

7 January 2021

Structural mechanism of endosome docking by the FYVE domain

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2802%2900028-1

7 January 2021

Epsin 1 undergoes nucleocytosolic shuttling and its eps15 interactor NH(2)-terminal homology (ENTH) domain, structurally similar to Armadillo and HEAT repeats, interacts with the transcription factor promyelocytic leukemia Zn(2)+ finger protein (PLZ

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2802%2900028-1

7 January 2021

A novel all helix fold of the AP180 amino-terminal domain for phosphoinositide binding and clathrin assembly in synaptic vesicle endocytosis

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2802%2900028-1

7 January 2021

Solution structure of the PX domain, a target of the SH3 domain

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2802%2900028-1

7 January 2021

Regulation of phosphoinositide-specific phospholipase C

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2802%2900028-1

7 January 2021

FYVE-DSP1, a dual-specificity protein phosphatase containing an FYVE domain

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2802%2900028-1

7 January 2021

FYVE-DSP2, a FYVE domain-containing dual specificity protein phosphatase that dephosphorylates phosphotidylinositol 3-phosphate

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2802%2900028-1

7 January 2021

Mouse p170 is a novel phosphatidylinositol 3-kinase containing a C2 domain

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2802%2900028-1

7 January 2021

Cpk is a novel class of Drosophila PtdIns 3-kinase containing a C2 domain

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2802%2900028-1

7 January 2021

Phospholipase C delta 1 requires a pleckstrin homology domain for interaction with the plasma membrane

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2802%2900028-1

7 January 2021

Identification and analysis of PH domain-containing targets of phosphatidylinositol 3-kinase using a novel in vivo assay in yeast

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2802%2900028-1

7 January 2021

Global analysis of protein activities using proteome chips

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2802%2900028-1

7 January 2021

Specific binding of the Akt-1 protein kinase to phosphatidylinositol 3,4,5-trisphosphate without subsequent activation

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2802%2900028-1

7 January 2021

High Affinity Binding of Inositol Phosphates and Phosphoinositides to the Pleckstrin Homology Domain of RAC/Protein Kinase B and Their Influence on Kinase Activity

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2802%2900028-1

7 January 2021

Clathrin- and AP-2-binding sites in HIP1 uncover a general assembly role for endocytic accessory proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2802%2900028-1

7 January 2021

The I/LWEQ module: a conserved sequence that signifies F-actin binding in functionally diverse proteins from yeast to mammals

1 reference

https://api.crossref.org/works/10.1016%2FS0898-6568%2802%2900028-1

7 January 2021

10.1016/S0898-6568(02)00028-1

Identifiers

DOI

1 reference

3 August 2017

1 reference