(Q34659907)

3 August 2017

title

Dysfunctional mitochondrial respiration in the striatum of the Huntington's disease transgenic R6/2 mouse model (English)

1 reference

3 August 2017

0 references

1 reference

Lis Frydenreich Hasholt

7

object named as

Lis Hasholt

1 reference

3 August 2017

3

Jørgen Kanters

1 reference

3 August 2017

author name string

Frederik Heurlin Aidt

1

1 reference

3 August 2017

Signe Marie Borch Nielsen

2

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3 August 2017

Dominik Pesta

4

1 reference

3 August 2017

Troels Tolstrup Nielsen

5

1 reference

3 August 2017

Anne Nørremølle

6

1 reference

3 August 2017

Michael Christiansen

8

1 reference

3 August 2017

Christian Munch Hagen

9

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3 August 2017

language of work or name

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2 April 2013

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3 August 2017

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3 August 2017

volume

5

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3 August 2017

page(s)

72-74

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Assessing mitochondrial dysfunction in cells.

3 August 2017

cites work

1 reference

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Mitochondrial structure and function are disrupted by standard isolation methods

7 July 2018

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Mutant huntingtin binds the mitochondrial fission GTPase dynamin-related protein-1 and increases its enzymatic activity

7 July 2018

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Abnormal mitochondrial dynamics, mitochondrial loss and mutant huntingtin oligomers in Huntington's disease: implications for selective neuronal damage

7 July 2018

1 reference

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Mitochondria in Huntington's disease

7 July 2018

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Sustained effects of nonallele-specific Huntingtin silencing

7 July 2018

1 reference

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From protons to OXPHOS supercomplexes and Alzheimer's disease: structure-dynamics-function relationships of energy-transducing membranes

7 July 2018

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Mitochondria and Huntington's disease pathogenesis: insight from genetic and chemical models

7 July 2018

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Impaired regulation of brain mitochondria by extramitochondrial Ca2+ in transgenic Huntington disease rats

7 July 2018

1 reference

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N-terminal mutant huntingtin associates with mitochondria and impairs mitochondrial trafficking

7 July 2018

1 reference

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Huntington's disease: from huntingtin function and dysfunction to therapeutic strategies.

7 July 2018

1 reference

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Involvement of mitochondrial complex II defects in neuronal death produced by N-terminus fragment of mutated huntingtin

7 July 2018

1 reference

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Heterogeneity in 1H-MRS profiles of presymptomatic and early manifest Huntington's disease

7 July 2018

1 reference

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Calcium, ATP, and ROS: a mitochondrial love-hate triangle

7 July 2018

1 reference

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Mutant huntingtin directly increases susceptibility of mitochondria to the calcium-induced permeability transition and cytochrome c release

7 July 2018

1 reference

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The energetics of Huntington's disease

7 July 2018

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Lessons from animal models of Huntington's disease

7 July 2018

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Early degenerative changes in transgenic mice expressing mutant huntingtin involve dendritic abnormalities but no impairment of mitochondrial energy production

7 July 2018

1 reference

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The Huntington's disease protein interacts with p53 and CREB-binding protein and represses transcription

7 July 2018

1 reference

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Mitochondrial dysfunction and free radical damage in the Huntington R6/2 transgenic mouse.

7 July 2018

1 reference

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Oxidative damage and metabolic dysfunction in Huntington's disease: selective vulnerability of the basal ganglia.

7 July 2018

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Striatal glucose metabolism and dopamine D2 receptor binding in asymptomatic gene carriers and patients with Huntington's disease

7 July 2018

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Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice

7 July 2018

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A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes.

7 July 2018

1 reference

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Trinucleotide repeat elongation in the Huntingtin gene in Huntington disease patients from 71 Danish families

7 July 2018

1 reference

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Neuropathological classification of Huntington's disease

7 July 2018

1 reference

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Development and implementation of standardized respiratory chain spectrophotometric assays for clinical diagnosis

7 July 2018

1 reference

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Detection of early behavioral markers of Huntington's disease in R6/2 mice employing an automated social home cage

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3614423

Weight loss in Huntington disease increases with higher CAG repeat number

26 October 2018

1 reference

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Increased caspase-2, calpain activations and decreased mitochondrial complex II activity in cells expressing exogenous huntingtin exon 1 containing CAG repeat in the pathogenic range

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3614423

Mitochondrial dysfunction in Huntington's disease: the bioenergetics of isolated and in situ mitochondria from transgenic mice

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3614423

The first 17 amino acids of Huntingtin modulate its sub-cellular localization, aggregation and effects on calcium homeostasis.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3614423

Mutant huntingtin aggregates impair mitochondrial movement and trafficking in cortical neurons

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3614423

p53 mediates cellular dysfunction and behavioral abnormalities in Huntington's disease

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3614423

Mitochondrial respiration and ATP production are significantly impaired in striatal cells expressing mutant huntingtin

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3614423

Evaluation of mitochondrial respiratory function in small biopsies of liver.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3614423

Metabolic network abnormalities in early Huntington's disease: an [(18)F]FDG PET study.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3614423

Metabolic and glutamatergic disturbances in the Huntington's disease transgenic mouse.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3614423

Mitochondrial defect in Huntington's disease caudate nucleus

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3614423

Evidence for impairment of energy metabolism in vivo in Huntington's disease using localized 1H NMR spectroscopy

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3614423

Differential regulation of respiratory chain subunits by a CREB-dependent signal transduction pathway. Role of cyclic AMP in cytochrome c and COXIV gene expression

26 October 2018

1 reference

12 December 2020

Compound heterozygous mutations in the flavoprotein gene of the respiratory chain complex II in a patient with Leigh syndrome

1 reference

12 December 2020

High-resolution respirometry: OXPHOS protocols for human cells and permeabilized fibers from small biopsies of human muscle

1 reference

12 December 2020

Mitochondrial respiratory control and early defects of oxidative phosphorylation in the failing human heart

1 reference

12 December 2020

10.1371/CURRENTS.HD.D8917B4862929772C5A2F2A34EF1C201

Identifiers

DOI

1 reference

3 August 2017

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3 August 2017

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