(Q34627072)

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Abnormal mitochondrial dynamics, mitochondrial loss and mutant huntingtin oligomers in Huntington's disease: implications for selective neuronal damage

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scholarly article

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Europe PubMed Central

3 August 2017

Abnormal mitochondrial dynamics, mitochondrial loss and mutant huntingtin oligomers in Huntington's disease: implications for selective neuronal damage (English)

1 reference

Europe PubMed Central

3 August 2017

Huntington's disease

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1 reference

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inferred from title

3

object named as

Maria Manczak

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Europe PubMed Central

3 August 2017

author name string

Ulziibat Shirendeb

1

1 reference

Europe PubMed Central

3 August 2017

Arubala P Reddy

2

1 reference

Europe PubMed Central

3 August 2017

Marcus J Calkins

4

1 reference

Europe PubMed Central

3 August 2017

Peizhong Mao

5

1 reference

Europe PubMed Central

3 August 2017

Danilo A Tagle

6

1 reference

Europe PubMed Central

3 August 2017

P Hemachandra Reddy

7

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Europe PubMed Central

3 August 2017

publication date

21 January 2011

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Europe PubMed Central

3 August 2017

Human Molecular Genetics

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Europe PubMed Central

3 August 2017

20

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Europe PubMed Central

3 August 2017

1438-1455

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Europe PubMed Central

3 August 2017

7

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Europe PubMed Central

3 August 2017

describes a project that uses

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Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3049363/fullTextXML

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inferred from PubMed Central ID database lookup

Dynamin-related protein 1 and mitochondrial fragmentation in neurodegenerative diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049363

7 July 2018

Mitochondrial fission and cristae disruption increase the response of cell models of Huntington's disease to apoptotic stimuli

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049363

7 July 2018

Mitochondrial loss, dysfunction and altered dynamics in Huntington's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049363

7 July 2018

Mitochondrial matters of the brain: the role in Huntington's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049363

7 July 2018

Mitochondria-targeted antioxidants protect against amyloid-beta toxicity in Alzheimer's disease neurons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049363

7 July 2018

Mutant huntingtin fragments form oligomers in a polyglutamine length-dependent manner in vitro and in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049363

7 July 2018

Abnormal morphology of peripheral cell tissues from patients with Huntington disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049363

7 July 2018

Identical oligomeric and fibrillar structures captured from the brains of R6/2 and knock-in mouse models of Huntington's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049363

7 July 2018

Impaired balance of mitochondrial fission and fusion in Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049363

7 July 2018

Loss of parkin or PINK1 function increases Drp1-dependent mitochondrial fragmentation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049363

7 July 2018

Mitochondrial structural and functional dynamics in Huntington's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049363

7 July 2018

Amyloid beta, mitochondrial structural and functional dynamics in Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049363

7 July 2018

Loss of PINK1 function promotes mitophagy through effects on oxidative stress and mitochondrial fission

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049363

7 July 2018

Adipose tissue dysfunction tracks disease progression in two Huntington's disease mouse models

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049363

7 July 2018

Amyloid-beta overproduction causes abnormal mitochondrial dynamics via differential modulation of mitochondrial fission/fusion proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049363

7 July 2018

Effects of overexpression of huntingtin proteins on mitochondrial integrity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049363

7 July 2018

Cyclophilin D deficiency attenuates mitochondrial and neuronal perturbation and ameliorates learning and memory in Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049363

7 July 2018

The Parkinson's disease genes pink1 and parkin promote mitochondrial fission and/or inhibit fusion in Drosophila

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049363

7 July 2018

N-terminal mutant huntingtin associates with mitochondria and impairs mitochondrial trafficking

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049363

7 July 2018

The PINK1/Parkin pathway regulates mitochondrial morphology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049363

7 July 2018

Amyloid beta, mitochondrial dysfunction and synaptic damage: implications for cognitive decline in aging and Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049363

7 July 2018

Huntingtin has a membrane association signal that can modulate huntingtin aggregation, nuclear entry and toxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049363

7 July 2018

Mitochondrial dysfunction in aging and Alzheimer's disease: strategies to protect neurons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049363

7 July 2018

Trinucleotide Repeat Disorders

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049363

7 July 2018

Extended polyglutamine repeats trigger a feedback loop involving the mitochondrial complex III, the proteasome and huntingtin aggregates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049363

7 July 2018

Selective defect of in vivo glycolysis in early Huntington's disease striatum

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049363

7 July 2018

Hypothesis: Huntingtin may function in membrane association and vesicular trafficking

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049363

7 July 2018

Mitochondria are a direct site of A beta accumulation in Alzheimer's disease neurons: implications for free radical generation and oxidative damage in disease progression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049363

7 July 2018

Brain imaging and cognitive dysfunctions in Huntington's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049363

7 July 2018

Huntingtin associates with acidic phospholipids at the plasma membrane

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049363

7 July 2018

Mutant huntingtin impairs axonal trafficking in mammalian neurons in vivo and in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049363

7 July 2018

Mutant huntingtin directly increases susceptibility of mitochondria to the calcium-induced permeability transition and cytochrome c release

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049363

7 July 2018

Rate and correlates of weight change in Huntington's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049363

7 July 2018

Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049363

7 July 2018

Early mitochondrial calcium defects in Huntington's disease are a direct effect of polyglutamines.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049363

7 July 2018

Huntingtin is present in the nucleus, interacts with the transcriptional corepressor C-terminal binding protein, and represses transcription

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049363

7 July 2018

New anti-huntingtin monoclonal antibodies: implications for huntingtin conformation and its binding proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049363

7 July 2018

Recent advances in understanding the pathogenesis of Huntington's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049363

7 July 2018

Oxidative stress in Huntington's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049363

7 July 2018

Frontal lobe volume in patients with Huntington's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049363

7 July 2018

Oxidative damage and metabolic dysfunction in Huntington's disease: selective vulnerability of the basal ganglia.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049363

7 July 2018

Reduced basal ganglia volume associated with the gene for Huntington's disease in asymptomatic at-risk persons.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049363

7 July 2018

Cerebral metabolism and atrophy in huntington's disease determined by18FDG and computed tomographic scan

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049363

7 July 2018

Positron emission tomographic scan investigations of Huntington's disease: cerebral metabolic correlates of cognitive function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049363

7 July 2018

PET scan investigations of Huntington's disease: cerebral metabolic correlates of neurological features and functional decline

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049363

7 July 2018

Positron emission tomography in the early diagnosis of Huntington's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049363

7 July 2018

Neuropathological classification of Huntington's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049363

7 July 2018

Clinical-pathologic correlation in Huntington's disease: a neuropsychological and computed tomography study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049363

7 July 2018

Cortical and subcortical glucose consumption measured by PET in patients with Huntington's disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049363

7 July 2018

Cerebral structure on MRI, part II: Specific changes in Alzheimer's and Huntington's diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049363

7 July 2018

History of genetic disease: the molecular genetics of Huntington disease - a history

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR024

21 January 2018

Wild-type huntingtin participates in protein trafficking between the Golgi and the extracellular space

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR024

21 January 2018

Hsp70 and Hsp40 attenuate formation of spherical and annular polyglutamine oligomers by partitioning monomer

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR024

21 January 2018

Huntingtin spheroids and protofibrils as precursors in polyglutamine fibrilization

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR024

21 January 2018

Polyglutamine disruption of the huntingtin exon 1 N terminus triggers a complex aggregation mechanism

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR024

21 January 2018

Longitudinal change in basal ganglia volume in patients with Huntington's disease

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR024

21 January 2018

Biochemical abnormalities and excitotoxicity in Huntington's disease brain.

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR024

21 January 2018

HD CAG repeat implicates a dominant property of huntingtin in mitochondrial energy metabolism

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR024

21 January 2018

Mutant huntingtin aggregates impair mitochondrial movement and trafficking in cortical neurons

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR024

21 January 2018

Could successful (mitochondrial) networking help prevent Huntington's disease?

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR024

21 January 2018

Single particle characterization of iron-induced pore-forming alpha-synuclein oligomers

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR024

21 January 2018

Progression of symptoms in the early and middle stages of Huntington disease

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR024

21 January 2018

Huntington's disease: clinical correlates of disability and progression

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR024

21 January 2018

Weight loss in Huntington disease increases with higher CAG repeat number

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR024

21 January 2018

The use of real-time PCR analysis in a gene expression study of Alzheimer's disease post-mortem brains

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR024

21 January 2018

Multimodal imaging of residual function and compensatory resource allocation in cortical atrophy: a case study of parietal lobe function in a patient with Huntington's disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3049363

26 October 2018

Identifiers

10.1093/HMG/DDR024

1 reference

Europe PubMed Central

3 August 2017

1 reference

Europe PubMed Central

3 August 2017

1 reference

Europe PubMed Central

3 August 2017

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