(Q34660993)

3 August 2017

Identification of propofol binding sites in a nicotinic acetylcholine receptor with a photoreactive propofol analog (English)

1 reference

3 August 2017

1 reference

Selwyn S Jayakar

1

1 reference

3 August 2017

William P Dailey

series ordinal

2

1 reference

3 August 2017

Roderic G Eckenhoff

series ordinal

3

1 reference

3 August 2017

Jonathan B Cohen

series ordinal

4

1 reference

3 August 2017

language of work or name

English

0 references

publication date

8 January 2013

1 reference

Journal of Biological Chemistry

3 August 2017

1 reference

3 August 2017

288

1 reference

3 August 2017

6178-6189

1 reference

3 August 2017

9

1 reference

Mapping general anesthetic binding site(s) in human α1β3 γ-aminobutyric acid type A receptors with [³H]TDBzl-etomidate, a photoreactive etomidate analogue

3 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3585054

p-(4-Azipentyl)propofol: a potent photoreactive general anesthetic derivative of propofol

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3585054

Single-channel and structural foundations of neuronal α7 acetylcholine receptor potentiation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3585054

Principles of activation and permeation in an anion-selective Cys-loop receptor

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3585054

X-ray structures of general anaesthetics bound to a pentameric ligand-gated ion channel

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3585054

Modeling anesthetic binding sites within the glycine alpha one receptor based on prokaryotic ion channel templates: the problem with TM4.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3585054

m-Azipropofol (AziPm) a photoactive analogue of the intravenous general anesthetic propofol

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3585054

Binding, activation and modulation of Cys-loop receptors.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3585054

Conformational changes in the nicotinic acetylcholine receptor during gating and desensitization

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3585054

[(3)H]chlorpromazine photolabeling of the torpedo nicotinic acetylcholine receptor identifies two state-dependent binding sites in the ion channel

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3585054

Mammalian nicotinic acetylcholine receptors: from structure to function

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3585054

X-ray structure of a pentameric ligand-gated ion channel in an apparently open conformation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3585054

Structure of a potentially open state of a proton-activated pentameric ligand-gated ion channel

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3585054

Potentiation of alpha7 nicotinic acetylcholine receptors via an allosteric transmembrane site

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3585054

Identification of binding sites in the nicotinic acetylcholine receptor for TDBzl-etomidate, a photoreactive positive allosteric effector

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3585054

General anaesthesia: from molecular targets to neuronal pathways of sleep and arousal

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3585054

Emerging molecular mechanisms of general anesthetic action.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3585054

Refined structure of the nicotinic acetylcholine receptor at 4A resolution

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3585054

Molecular and neuronal substrates for general anaesthetics

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3585054

General anesthetic potencies of a series of propofol analogs correlate with potency for potentiation of gamma-aminobutyric acid (GABA) current at the GABA(A) receptor but not with lipid solubility

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3585054

Tricine-sodium dodecyl sulfate-polyacrylamide gel electrophoresis for the separation of proteins in the range from 1 to 100 kDa

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3585054

Alpha 4 beta 2 neuronal nicotinic acetylcholine receptors in the central nervous system are inhibited by isoflurane and propofol, but alpha 7-type nicotinic acetylcholine receptors are unaffected.

7 July 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.435909

Differential sensitivities of mammalian neuronal and muscle nicotinic acetylcholine receptors to general anesthetics.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.435909

Identification of a GABAA receptor anesthetic binding site at subunit interfaces by photolabeling with an etomidate analog.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.435909

Multiple transmembrane binding sites for p-trifluoromethyldiazirinyl-etomidate, a photoreactive Torpedo nicotinic acetylcholine receptor allosteric inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.435909

Gating-enhanced accessibility of hydrophobic sites within the transmembrane region of the nicotinic acetylcholine receptor's {delta}-subunit. A time-resolved photolabeling study

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.435909

Probing the structure of the affinity-purified and lipid-reconstituted torpedo nicotinic acetylcholine receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.435909

Identification of sites of incorporation in the nicotinic acetylcholine receptor of a photoactivatible general anesthetic.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.435909

[3H]Benzophenone photolabeling identifies state-dependent changes in nicotinic acetylcholine receptor structure.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.435909

Identification of Nicotinic Acetylcholine Receptor Amino Acids Photolabeled by the Volatile Anesthetic Halothane

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.435909

Photoaffinity labeling the torpedo nicotinic acetylcholine receptor with [(3)H]tetracaine, a nondesensitizing noncompetitive antagonist.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3585054

Photolabeling of membrane-bound Torpedo nicotinic acetylcholine receptor with the hydrophobic probe 3-trifluoromethyl-3-(m-[125I]iodophenyl)diazirine

26 October 2018

1 reference

12 December 2020

The hydrophobic photoreagent 3-(trifluoromethyl)-3-m-([125I] iodophenyl) diazirine is a novel noncompetitive antagonist of the nicotinic acetylcholine receptor

1 reference

12 December 2020

Agonist-induced changes in the structure of the acetylcholine receptor M2 regions revealed by photoincorporation of an uncharged nicotinic noncompetitive antagonist

1 reference

12 December 2020

Identifying the lipid-protein interface of the Torpedo nicotinic acetylcholine receptor: secondary structure implications

1 reference

12 December 2020

Conformations of Torpedo acetylcholine receptor associated with ion transport and desensitization

1 reference

12 December 2020

Multiple affinity states for noncompetitive blockers revealed by [3H]phencyclidine binding to acetylcholine receptor rich membrane fragments from Torpedo marmorata

1 reference

12 December 2020

Use of o-phthalaldehyde to reduce background during automated Edman degradation

1 reference

12 December 2020

Desensitization of membrane-bound Torpedo acetylcholine receptor by amine noncompetitive antagonists and aliphatic alcohols: studies of [3H]acetylcholine binding and sodium-22 ion fluxes

1 reference

12 December 2020

Mapping of the acetylcholine binding site of the nicotinic acetylcholine receptor: [3H]nicotine as an agonist photoaffinity label

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M112.435909

1 reference

3 August 2017

1 reference

3 August 2017

1 reference