(Q34663576)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23577068%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

title

Prion protein is decreased in Alzheimer's brain and inversely correlates with BACE1 activity, amyloid-β levels and Braak stage (English)

1 reference

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28 February 2020

0 references

0 references

Elizabeth B C Glennon

3

1 reference

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28 February 2020

Patrick G. Kehoe

4

1 reference

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28 February 2020

Katherine A B Kellett

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23577068%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

Nigel Mark Hooper

7

1 reference

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28 February 2020

author name string

Isobel J Whitehouse

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23577068%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

J Scott Miners

2

1 reference

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28 February 2020

Seth Love

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23577068%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

language of work or name

English

0 references

publication date

5 April 2013

1 reference

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28 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23577068%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

volume

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23577068%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

issue

4

1 reference

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28 February 2020

page(s)

e59554

1 reference

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Creative Commons Attribution 4.0 International

28 February 2020

copyright license

start time

5 April 2013

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

Prion protein facilitates uptake of zinc into neuronal cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3618446

Cellular prion protein expression is not regulated by the Alzheimer's amyloid precursor protein intracellular domain

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3618446

Prion protein interacts with BACE1 protein and differentially regulates its activity toward wild type and Swedish mutant amyloid precursor protein.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3618446

Unaltered prion protein expression in Alzheimer disease patients

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3618446

Genetic variation and neuroimaging measures in Alzheimer disease

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3618446

Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3618446

7 July 2018

1 reference

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The role of amyloid precursor protein processing by BACE1, the beta-secretase, in Alzheimer disease pathophysiology

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3618446

The in vivo brain interactome of the amyloid precursor protein

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3618446

Cellular prion protein regulates beta-secretase cleavage of the Alzheimer's amyloid precursor protein

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3618446

The elephant in the room - healthy brains in later life, epidemiology and public health

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3618446

Reaching the population with dementia drugs: what are the challenges?

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3618446

LRRTM3 promotes processing of amyloid-precursor protein by BACE1 and is a positional candidate gene for late-onset Alzheimer's disease

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3618446

Alzheimer disease: progress or profit?

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3618446

Down syndrome, Alzheimer's disease and seizures

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3618446

Tau pathology in Alzheimer disease and other tauopathies

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3618446

Reticulon family members modulate BACE1 activity and amyloid-beta peptide generation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3618446

Amyloid beta peptide load is correlated with increased beta-secretase activity in sporadic Alzheimer's disease patients

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3618446

Beta-secretase activity increases with aging in human, monkey, and mouse brain.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3618446

Caspr regulates the processing of contactin and inhibits its binding to neurofascin

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3618446

Contribution by synaptic zinc to the gender-disparate plaque formation in human Swedish mutant APP transgenic mice

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3618446

Contactin-associated protein (Caspr) and contactin form a complex that is targeted to the paranodal junctions during myelination.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3618446

Identification of a novel contactin-associated transmembrane receptor with multiple domains implicated in protein-protein interactions

7 July 2018

1 reference

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Rapid induction of Alzheimer A beta amyloid formation by zinc.

7 July 2018

1 reference

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The Consortium to Establish a Registry for Alzheimer's Disease (CERAD). Part I. Clinical and neuropsychological assessment of Alzheimer's disease

7 July 2018

1 reference

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Neuropathological stageing of Alzheimer-related changes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3618446

Extracellular neurofibrillary tangles reflect neuronal loss and provide further evidence of extensive protein cross-linking in Alzheimer disease.

7 July 2018

1 reference

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Beta-secretase protein and activity are increased in the neocortex in Alzheimer disease

21 January 2018

1 reference

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Changes with age in the activities of beta-secretase and the Abeta-degrading enzymes neprilysin, insulin-degrading enzyme and angiotensin-converting enzyme.

21 January 2018

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A new take on prions: preventing Alzheimer's disease

21 January 2018

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Prion protein is reduced in aging and in sporadic but not in familial Alzheimer's disease.

21 January 2018

1 reference

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Site-specific characterization of the N-linked glycans of murine prion protein by high-performance liquid chromatography/electrospray mass spectrometry and exoglycosidase digestions

21 January 2018

1 reference

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p53-Dependent transcriptional control of cellular prion by presenilins.

21 January 2018

1 reference

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A role for synaptic zinc in activity-dependent Abeta oligomer formation and accumulation at excitatory synapses.

21 January 2018

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Higher soluble amyloid beta concentration in frontal cortex of young adults than in normal elderly or Alzheimer's disease.

21 January 2018

1 reference

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Oligomeric Abeta in Alzheimer's disease: relationship to plaque and tangle pathology, APOE genotype and cerebral amyloid angiopathy.

21 January 2018

1 reference

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APOE epsilon 4 influences the pathological phenotype of Alzheimer's disease by favouring cerebrovascular over parenchymal accumulation of A beta protein.

21 January 2018

1 reference

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Cholinesterase inhibitors reduce cortical Abeta in dementia with Lewy bodies.

21 January 2018

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Neprilysin and insulin-degrading enzyme levels are increased in Alzheimer disease in relation to disease severity.

21 January 2018

1 reference

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Zinc transporter mRNA levels in Alzheimer's disease postmortem brain.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3618446

Accumulation of insoluble amyloid-β in down's syndrome is associated with increased BACE-1 and neprilysin activities.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3618446

10.1371/JOURNAL.PONE.0059554

26 October 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23577068%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23577068%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23577068%20AND%20SRC:MED&resulttype=core&format=json