(Q46064935)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19339596%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

title

A role for synaptic zinc in activity-dependent Abeta oligomer formation and accumulation at excitatory synapses (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19339596%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

2

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25 January 2020

author name string

Atul Deshpande

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19339596%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

Raju Metherate

3

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19339596%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

Charles G Glabe

4

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19339596%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

Jorge Busciglio

5

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25 January 2020

language of work or name

English

0 references

publication date

1 April 2009

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19339596%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

published in

Journal of Neuroscience

1 reference

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25 January 2020

volume

29

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25 January 2020

issue

13

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25 January 2020

page(s)

4004-4015

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Soluble amyloid beta peptide concentration as a predictor of synaptic change in Alzheimer's disease

25 January 2020

cites work

1 reference

12 December 2020

Soluble pool of Abeta amyloid as a determinant of severity of neurodegeneration in Alzheimer's disease

1 reference

12 December 2020

Correlation between elevated levels of amyloid beta-peptide in the brain and cognitive decline

1 reference

12 December 2020

Amyloid beta interacts with the amyloid precursor protein: a potential toxic mechanism in Alzheimer's disease.

1 reference

12 December 2020

High-level neuronal expression of abeta 1-42 in wild-type human amyloid protein precursor transgenic mice: synaptotoxicity without plaque formation

1 reference

12 December 2020

Characterization of Copper Interactions with Alzheimer Amyloid β Peptides

1 reference

12 December 2020

Alzheimer's disease amyloid-beta binds copper and zinc to generate an allosterically ordered membrane-penetrating structure containing superoxide dismutase-like subunits

1 reference

12 December 2020

Treatment with a copper-zinc chelator markedly and rapidly inhibits beta-amyloid accumulation in Alzheimer's disease transgenic mice.

1 reference

12 December 2020

Soluble oligomers of beta amyloid (1-42) inhibit long-term potentiation but not long-term depression in rat dentate gyrus.

1 reference

12 December 2020

Synaptically released zinc: physiological functions and pathological effects.

1 reference

12 December 2020

Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo

1 reference

12 December 2020

Mapping the binding site of the neuroprotectant ifenprodil on NMDA receptors.

1 reference

12 December 2020

The role of tau in Alzheimer's disease

1 reference

12 December 2020

Beta-amyloid deposition and neurofibrillary tangle association with caspase activation in Down syndrome

1 reference

12 December 2020

Apolipoprotein E enhances uptake of soluble but not aggregated amyloid-beta protein into synaptic terminals

1 reference

12 December 2020

APP processing and synaptic function

1 reference

12 December 2020

Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis

1 reference

12 December 2020

GVS-111 prevents oxidative damage and apoptosis in normal and Down's syndrome human cortical neurons.

1 reference

12 December 2020

Alzheimer's disease-affected brain: presence of oligomeric A beta ligands (ADDLs) suggests a molecular basis for reversible memory loss

1 reference

12 December 2020

Femtomole Immunodetection of Synthetic and Endogenous Amyloid-β Oligomers and Its Application to Alzheimer's Disease Drug Candidate Screening

1 reference

12 December 2020

Permeabilization of lipid bilayers is a common conformation-dependent activity of soluble amyloid oligomers in protein misfolding diseases

1 reference

12 December 2020

Conformation-dependent antibodies target diseases of protein misfolding

1 reference

12 December 2020

Dendrite and dendritic spine alterations in Alzheimer models

1 reference

12 December 2020

Molecular dynamics simulations of spontaneous fibril formation by random-coil peptides

1 reference

12 December 2020

Synaptic targeting by Alzheimer's-related amyloid beta oligomers.

1 reference

12 December 2020

Natural oligomers of the amyloid-beta protein specifically disrupt cognitive function

1 reference

12 December 2020

NMDA receptor activation mediates copper homeostasis in hippocampal neurons

1 reference

12 December 2020

Nanoparticle-based detection in cerebral spinal fluid of a soluble pathogenic biomarker for Alzheimer's disease

1 reference

12 December 2020

Intraneuronal Abeta causes the onset of early Alzheimer's disease-related cognitive deficits in transgenic mice

1 reference

12 December 2020

The neurobiology of zinc in health and disease

1 reference

12 December 2020

Brain, aging and neurodegeneration: role of zinc ion availability

1 reference

12 December 2020

Regulation of NMDA receptor trafficking by amyloid-beta

1 reference

12 December 2020

Dendritic spine abnormalities in amyloid precursor protein transgenic mice demonstrated by gene transfer and intravital multiphoton microscopy

1 reference

12 December 2020

Temporal profile of amyloid-beta (Abeta) oligomerization in an in vivo model of Alzheimer disease. A link between Abeta and tau pathology

1 reference

12 December 2020

Soluble beta-amyloid1-40 induces NMDA-dependent degradation of postsynaptic density-95 at glutamatergic synapses.

1 reference

12 December 2020

Synaptic activity regulates interstitial fluid amyloid-beta levels in vivo.

1 reference

12 December 2020

Zinc and copper: pharmacological probes and endogenous modulators of neuronal excitability.

1 reference

12 December 2020

Common structure and toxic function of amyloid oligomers implies a common mechanism of pathogenesis

1 reference

12 December 2020

Effects of secreted oligomers of amyloid beta-protein on hippocampal synaptic plasticity: a potent role for trimers.

1 reference

12 December 2020

A specific amyloid-beta protein assembly in the brain impairs memory

1 reference

12 December 2020

Incidence and predictors of seizures in patients with Alzheimer's disease

1 reference

12 December 2020

The molecular pathology of Alzheimer's disease

1 reference

12 December 2020

Different conformations of amyloid beta induce neurotoxicity by distinct mechanisms in human cortical neurons.

1 reference

12 December 2020

Role of the Menkes copper-transporting ATPase in NMDA receptor-mediated neuronal toxicity

1 reference

12 December 2020

Conformation-dependent anti-amyloid oligomer antibodies

1 reference

12 December 2020

A century of Alzheimer's disease

1 reference

12 December 2020

Monoclonal antibodies that target pathological assemblies of Abeta.

1 reference

12 December 2020

Blocking the apolipoprotein E/amyloid-beta interaction as a potential therapeutic approach for Alzheimer's disease

1 reference

12 December 2020

Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer's amyloid beta-peptide

1 reference

12 December 2020

Learning decreases A beta*56 and tau pathology and ameliorates behavioral decline in 3xTg-AD mice.

1 reference

12 December 2020

A Oligomer-Induced Aberrations in Synapse Composition, Shape, and Density Provide a Molecular Basis for Loss of Connectivity in Alzheimer's Disease

1 reference

12 December 2020

Small molecule inhibitors of aggregation indicate that amyloid beta oligomerization and fibrillization pathways are independent and distinct

1 reference

12 December 2020

Soluble beta-amyloid[25-35] reversibly impairs hippocampal synaptic plasticity and spatial learning.

1 reference

12 December 2020

Natural oligomers of the Alzheimer amyloid-beta protein induce reversible synapse loss by modulating an NMDA-type glutamate receptor-dependent signaling pathway

1 reference

12 December 2020

Amyloid beta oligomers induce impairment of neuronal insulin receptors

1 reference

12 December 2020

Aberrant excitatory neuronal activity and compensatory remodeling of inhibitory hippocampal circuits in mouse models of Alzheimer's disease

1 reference

12 December 2020

Fibril specific, conformation dependent antibodies recognize a generic epitope common to amyloid fibrils and fibrillar oligomers that is absent in prefibrillar oligomers

1 reference

12 December 2020

Tau isoform expression and regulation in human cortical neurons

1 reference

12 December 2020

Zinc-mediated transactivation of TrkB potentiates the hippocampal mossy fiber-CA3 pyramid synapse

1 reference

12 December 2020

Rapid restoration of cognition in Alzheimer's transgenic mice with 8-hydroxy quinoline analogs is associated with decreased interstitial Abeta

1 reference

12 December 2020

Rapid induction of Alzheimer A beta amyloid formation by zinc.

1 reference

12 December 2020

Modulation of A beta adhesiveness and secretase site cleavage by zinc.

1 reference

12 December 2020

Release of amyloid beta-protein precursor derivatives by electrical depolarization of rat hippocampal slices

1 reference

12 December 2020

Water-soluble Abeta (N-40, N-42) oligomers in normal and Alzheimer disease brains.

1 reference

12 December 2020

Alpha2-macroglobulin complexes with and mediates the endocytosis of beta-amyloid peptide via cell surface low-density lipoprotein receptor-related protein.

1 reference

12 December 2020

Alpha2-macroglobulin associates with beta-amyloid peptide and prevents fibril formation

1 reference

12 December 2020

Diffusible, nonfibrillar ligands derived from Abeta1-42 are potent central nervous system neurotoxins

1 reference

12 December 2020

Elimination of zinc from synaptic vesicles in the intact mouse brain by disruption of the ZnT3 gene

1 reference

12 December 2020

10.1523/JNEUROSCI.5980-08.2009

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19339596%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

1 reference

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25 January 2020

PubMed publication ID

19339596

1 reference