(Q34677721)

3 August 2017

title

Pathological roles of the VEGF/SphK pathway in Niemann-Pick type C neurons (English)

1 reference

cellular response to vascular endothelial growth factor stimulus

3 August 2017

1 reference

GOA release 2020-03-11

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GOA release 2020-03-11

Sphingosine kinase 1

1 reference

GOA release 2020-03-11

14

Edward H Schuchman

1 reference

3 August 2017

Hyun Lee

1

1 reference

3 August 2017

Jong Kil Lee

2

1 reference

3 August 2017

Min Hee Park

3

1 reference

3 August 2017

Yu Ri Hong

4

1 reference

3 August 2017

Hugo H Marti

5

1 reference

3 August 2017

Hyongbum Kim

6

1 reference

3 August 2017

Yohei Okada

7

1 reference

3 August 2017

Makoto Otsu

8

1 reference

3 August 2017

Eul-Ju Seo

9

1 reference

3 August 2017

Jae-Hyung Park

10

1 reference

3 August 2017

Jae-Hoon Bae

11

1 reference

3 August 2017

Nozomu Okino

12

1 reference

3 August 2017

Xingxuan He

13

1 reference

3 August 2017

Jae-Sung Bae

15

1 reference

3 August 2017

Hee Kyung Jin

16

1 reference

3 August 2017

language of work or name

English

0 references

publication date

24 November 2014

1 reference

3 August 2017

published in

Nature Communications

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3 August 2017

volume

5

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3 August 2017

page(s)

5514

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Creative Commons Attribution 4.0 International

3 August 2017

copyright license

start time

24 November 2014

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4263144/fullTextXML

inferred from PubMed Central ID database lookup

exact match

https://scigraph.springernature.com/pub.10.1038/ncomms6514

0 references

cites work

Genetic and chemical correction of cholesterol accumulation and impaired autophagy in hepatic and neural cells derived from Niemann-Pick Type C patient-specific iPS cells.

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Niemann-Pick Disease Type C: Induced Pluripotent Stem Cell-Derived Neuronal Cells for Modeling Neural Disease and Evaluating Drug Efficacy

7 July 2018

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Niemann-Pick type C1 patient-specific induced pluripotent stem cells display disease specific hallmarks

7 July 2018

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Mitochondrial dysfunction associated with increased oxidative stress and α-synuclein accumulation in PARK2 iPSC-derived neurons and postmortem brain tissue

7 July 2018

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Tracking sphingosine metabolism and transport in sphingolipidoses: NPC1 deficiency as a test case

7 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263144

Vascular endothelial growth factor ameliorates the ataxic phenotype in a mouse model of spinocerebellar ataxia type 1.

7 July 2018

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TFEB links autophagy to lysosomal biogenesis

7 July 2018

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Cyclodextrin induces calcium-dependent lysosomal exocytosis

7 July 2018

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Vascular endothelial growth factor and its high-affinity receptor (VEGFR-2) are highly expressed in the human forebrain and cerebellum during development.

7 July 2018

1 reference

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Niemann-Pick disease type C1 is a sphingosine storage disease that causes deregulation of lysosomal calcium

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263144

Induction of pluripotent stem cells from adult human fibroblasts by defined factors

7 July 2018

1 reference

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Cholesterol accumulation is associated with lysosomal dysfunction and autophagic stress in Npc1 -/- mouse brain

7 July 2018

1 reference

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p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy

7 July 2018

1 reference

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Generation of germline-competent induced pluripotent stem cells

7 July 2018

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Bone marrow-derived mesenchymal stem cells promote neuronal networks with functional synaptic transmission after transplantation into mice with neurodegeneration

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263144

VEGF receptor signalling - in control of vascular function

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263144

Cell-autonomous death of cerebellar purkinje neurons with autophagy in Niemann-Pick type C disease

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263144

Fluorescence-based assay of sphingosine kinases

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263144

Niemann-Pick disease type C.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263144

Sphingosine-1-phosphate: an enigmatic signalling lipid

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263144

Biodegradable nanoparticles for drug and gene delivery to cells and tissue

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263144

Sphingosine kinase mediates vascular endothelial growth factor-induced activation of ras and mitogen-activated protein kinases

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263144

Sphingosine-1-phosphate and lipid phosphohydrolases

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263144

Recombinant proteins for neurodegenerative diseases: the delivery issue

7 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263144

PTK787/ZK 222584, a novel and potent inhibitor of vascular endothelial growth factor receptor tyrosine kinases, impairs vascular endothelial growth factor-induced responses and tumor growth after oral administration

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263144

Lipid changes in Niemann-Pick disease type C brain: personal experience and review of the literature

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263144

Tumor necrosis factor- induces adhesion molecule expression through the sphingosine kinase pathway

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263144

Development of a self-inactivating lentivirus vector.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263144

Murine model of Niemann-Pick C disease: mutation in a cholesterol homeostasis gene

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263144

Sphingosine-1-phosphate as second messenger in cell proliferation induced by PDGF and FCS mitogens

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263144

Angiogenesis in cancer, vascular, rheumatoid and other disease

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263144

Bone marrow-derived mesenchymal stem cells prevent the loss of Niemann-Pick type C mouse Purkinje neurons by correcting sphingolipid metabolism and increasing sphingosine-1-phosphate

7 July 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS6514

Cross-talk between human mesenchymal stem/progenitor cells (MSCs) and rat hippocampal slices in LPS-stimulated cocultures: the MSCs are activated to secrete prostaglandin E2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS6514

Correction: Uncoupling of Longevity and Telomere Length in C. elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS6514

In search of an "autophagomometer".

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS6514

Inhibition of the SERCA Ca2+ pumps by curcumin. Curcumin putatively stabilizes the interaction between the nucleotide-binding and phosphorylation domains in the absence of ATP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS6514

Niemann-Pick type C disease involves disrupted neurosteroidogenesis and responds to allopregnanolone

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS6514

The autophagic defect in Niemann-Pick disease type C neurons differs from somatic cells and reduces neuronal viability.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS6514

Definitive proof for direct reprogramming of hematopoietic cells to pluripotency.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS6514

Spatiotemporal recapitulation of central nervous system development by murine embryonic stem cell-derived neural stem/progenitor cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS6514

Low density lipoprotein (LDL)-mediated suppression of cholesterol synthesis and LDL uptake is defective in Niemann-Pick type C fibroblasts

21 January 2018

1 reference

12 December 2020

Matrix-binding vascular endothelial growth factor (VEGF) isoforms guide granule cell migration in the cerebellum via VEGF receptor Flk1

1 reference

12 December 2020

Neurodegeneration augments the ability of bone marrow-derived mesenchymal stem cells to fuse with Purkinje neurons in Niemann-Pick type C mice

1 reference

12 December 2020

Involvement of sphingosine 1-phosphate in nerve growth factor-mediated neuronal survival and differentiation

1 reference

12 December 2020

VEGF overexpression induces post-ischaemic neuroprotection, but facilitates haemodynamic steal phenomena

1 reference

12 December 2020

Pharmacokinetic characterization of 14C-vascular endothelial growth factor controlled release microspheres using a rat model

1 reference

12 December 2020

Identifiers

DOI

10.1038/NCOMMS6514

1 reference

Dimensions Publication ID

3 August 2017

0 references

1029496926

0 references

Fatcat ID

release_v5esv3d5xbeqjd6boi5o2nq25i

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/v5esv3d5xbeqjd6boi5o2nq25i

24 November 2022

mapped directly with Wikidata item

PMC publication ID

4263144

1 reference

3 August 2017

1 reference