(Q34678052)

3 August 2017

title

Kukoamine B, a novel dual inhibitor of LPS and CpG DNA, is a potential candidate for sepsis treatment (English)

1 reference

3 August 2017

0 references

Xin Liu

1

1 reference

3 August 2017

Xinchuan Zheng

2

1 reference

3 August 2017

Ning Wang

3

1 reference

3 August 2017

Hongwei Cao

4

1 reference

3 August 2017

Yongling Lu

5

1 reference

3 August 2017

Yupeng Long

6

1 reference

3 August 2017

Kecen Zhao

7

1 reference

3 August 2017

Hong Zhou

8

1 reference

3 August 2017

Jiang Zheng

9

1 reference

3 August 2017

language of work or name

English

0 references

publication date

1 March 2011

1 reference

British Journal of Pharmacology

3 August 2017

published in

1 reference

3 August 2017

volume

162

1 reference

3 August 2017

issue

6

1 reference

3 August 2017

page(s)

1274-1290

1 reference

The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors

3 August 2017

cites work

1 reference

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Signaling crosstalk during sequential TLR4 and TLR9 activation amplifies the inflammatory response of mouse macrophages.

7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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Targeting CpG DNA to screen and isolate anti-sepsis fraction and monomers from traditional Chinese herbs using affinity biosensor technology

7 July 2018

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Experimental therapeutic strategies for severe sepsis: mediators and mechanisms

7 July 2018

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Sepsis: links between pathogen sensing and organ damage

7 July 2018

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The influence of N-acetyl-L-cysteine on oxidative stress and nitric oxide synthesis in stimulated macrophages treated with a mustard gas analogue

7 July 2018

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Targeting the lipopolysaccharides: still a matter of debate?

7 July 2018

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TRAM couples endocytosis of Toll-like receptor 4 to the induction of interferon-beta

7 July 2018

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7 July 2018

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IL-1R1/MyD88 signaling and the inflammasome are essential in pulmonary inflammation and fibrosis in mice

7 July 2018

1 reference

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The family of five: TIR-domain-containing adaptors in Toll-like receptor signalling

7 July 2018

1 reference

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Regulation and function of IKK and IKK-related kinases

7 July 2018

1 reference

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DAMPs, PAMPs and alarmins: all we need to know about danger

7 July 2018

1 reference

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Phosphoinositide-mediated adaptor recruitment controls Toll-like receptor signaling

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058161

The myristoylation of TRIF-related adaptor molecule is essential for Toll-like receptor 4 signal transduction

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058161

Animal models of sepsis: setting the stage

7 July 2018

1 reference

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Drotrecogin alfa (activated) for adults with severe sepsis and a low risk of death

7 July 2018

1 reference

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The "cytokine profile": a code for sepsis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058161

Tamm-Horsfall glycoprotein links innate immune cell activation with adaptive immunity via a Toll-like receptor-4-dependent mechanism.

7 July 2018

1 reference

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Temperature dependence of the binding of endotoxins to the polycationic peptides polymyxin B and its nonapeptide

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058161

Regulation of Toll/IL-1-receptor-mediated gene expression by the inducible nuclear protein IkappaBzeta

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058161

Towards antibacterial strategies: studies on the mechanisms of interaction between antibacterial peptides and model membranes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058161

The epidemiology of sepsis in the United States from 1979 through 2000

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058161

The pathophysiology and treatment of sepsis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058161

Medicinal chemistry and therapeutic potential of CpG DNA.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058161

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058161

Macrophages exposed continuously to lipopolysaccharide and other agonists that act via toll-like receptors exhibit a sustained and additive activation state

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058161

A Toll-like receptor recognizes bacterial DNA

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058161

A conserved structural motif for lipopolysaccharide recognition by procaryotic and eucaryotic proteins

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058161

Cutting edge: Toll-like receptor 4 (TLR4)-deficient mice are hyporesponsive to lipopolysaccharide: evidence for TLR4 as the Lps gene product

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058161

E5531, a pure endotoxin antagonist of high potency

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058161

Polymyxin-B inhibition of LPS-induced interleukin-1 secretion by human monocytes is dependent upon the LPS origin.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058161

Differential stimulation of murine lymphoma growth in vitro by normal and BCG-activated macrophages

7 July 2018

1 reference

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Rapid increase in hospitalization and mortality rates for severe sepsis in the United States: a trend analysis from 1993 to 2003.

7 July 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2010.01114.X

The screening and isolation of an effective anti-endotoxin monomer from Radix Paeoniae Rubra using affinity biosensor technology

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2010.01114.X

A synthetic peptide derived from bactericidal/permeability-increasing protein neutralizes endotoxin in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2010.01114.X

Sequential control of Toll-like receptor-dependent responses by IRAK1 and IRAK2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2010.01114.X

Role of p38 MAPK in LPS induced pro-inflammatory cytokine and chemokine gene expression in equine leukocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2010.01114.X

Findings halt clinical trials of centoxin

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058161

Bacterial DNA induces NK cells to produce IFN-gamma in vivo and increases the toxicity of lipopolysaccharides.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058161

Bacterial DNA causes septic shock

26 October 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2010.01114.X

Development and application of surface plasmon resonance-based biosensors for the detection of cell-ligand interactions

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21108626

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1111/J.1476-5381.2010.01114.X

1 reference

3 August 2017

1 reference

3 August 2017

1 reference