(Q34680105)

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Consolidation of the cancer genome into domains of repressive chromatin by long-range epigenetic silencing (LRES) reduces transcriptional plasticity

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

Consolidation of the cancer genome into domains of repressive chromatin by long-range epigenetic silencing (LRES) reduces transcriptional plasticity (English)

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

Marcel W Coolen

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Marcel W Coolen

1

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Mark Cowley

10

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Mark D. Robinson

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Mark D Robinson

13

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Carlos S Moreno

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Carlos S Moreno

6

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Susan J Clark

14

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Clare Stirzaker

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Clare Stirzaker

2

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9

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Terence P Speed

1 reference

Europe PubMed Central

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3 August 2017

11

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Paul Lacaze

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Europe PubMed Central

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3 August 2017

author name string

Jenny Z Song

3

1 reference

Europe PubMed Central

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3 August 2017

Aaron L Statham

4

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

Zena Kassir

5

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

Andrew N Young

7

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

Vijay Varma

8

1 reference

Europe PubMed Central

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3 August 2017

Warren Kaplan

12

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Europe PubMed Central

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3 August 2017

publication date

21 February 2010

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Europe PubMed Central

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3 August 2017

Nature Cell Biology

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Europe PubMed Central

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3 August 2017

12

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

3

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

235-246

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

Cancer stem cells: mirage or reality?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058354

7 July 2018

Genome-wide profiling of histone h3 lysine 4 and lysine 27 trimethylation reveals an epigenetic signature in prostate carcinogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058354

7 July 2018

The putative tumor suppressor microRNA-101 modulates the cancer epigenome by repressing the polycomb group protein EZH2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058354

7 July 2018

miR-205 Exerts tumor-suppressive functions in human prostate through down-regulation of protein kinase Cepsilon.

1 reference

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7 July 2018

Large histone H3 lysine 9 dimethylated chromatin blocks distinguish differentiated from embryonic stem cells

1 reference

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7 July 2018

H3K27me3 forms BLOCs over silent genes and intergenic regions and specifies a histone banding pattern on a mouse autosomal chromosome

1 reference

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7 July 2018

Genomic loss of microRNA-101 leads to overexpression of histone methyltransferase EZH2 in cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058354

7 July 2018

Agglomerative epigenetic aberrations are a common event in human breast cancer

1 reference

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7 July 2018

Frequent switching of Polycomb repressive marks and DNA hypermethylation in the PC3 prostate cancer cell line

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058354

7 July 2018

Double strand breaks can initiate gene silencing and SIRT1-dependent onset of DNA methylation in an exogenous promoter CpG island

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058354

7 July 2018

A chromatin-wide transition to H4K20 monomethylation impairs genome integrity and programmed DNA rearrangements in the mouse

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058354

7 July 2018

Domain organization of human chromosomes revealed by mapping of nuclear lamina interactions

1 reference

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7 July 2018

An embryonic stem cell-like gene expression signature in poorly differentiated aggressive human tumors

1 reference

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7 July 2018

Expression changes of CAV1 and EZH2, located on 7q31 approximately q36, are rarely related to genomic alterations in primary prostate carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058354

7 July 2018

A polycomb group protein, PHF1, is involved in the response to DNA double-strand breaks in human cell

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058354

7 July 2018

Ancora: a web resource for exploring highly conserved noncoding elements and their association with developmental regulatory genes

1 reference

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7 July 2018

Epigenetic inactivation of a cluster of genes flanking MLH1 in microsatellite-unstable colorectal cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058354

7 July 2018

Physical plasticity of the nucleus in stem cell differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058354

7 July 2018

MicroRNA-29 family reverts aberrant methylation in lung cancer by targeting DNA methyltransferases 3A and 3B

1 reference

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7 July 2018

Genomic profiling of CpG methylation and allelic specificity using quantitative high-throughput mass spectrometry: critical evaluation and improvements

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058354

7 July 2018

Phenotypic plasticity and the epigenetics of human disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058354

7 July 2018

High-resolution profiling of histone methylations in the human genome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058354

7 July 2018

Epigenetic signatures of stem-cell identity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058354

7 July 2018

The epigenomics of cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058354

7 July 2018

A stem cell-like chromatin pattern may predispose tumor suppressor genes to DNA hypermethylation and heritable silencing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058354

7 July 2018

Epigenetic stem cell signature in cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058354

7 July 2018

Polycomb-mediated methylation on Lys27 of histone H3 pre-marks genes for de novo methylation in cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058354

7 July 2018

Integrative molecular concept modeling of prostate cancer progression.

1 reference

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7 July 2018

The cancer epigenome--components and functional correlates

1 reference

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7 July 2018

Regional copy number-independent deregulation of transcription in cancer

1 reference

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7 July 2018

Epigenetic inactivation of the HOXA gene cluster in breast cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058354

7 July 2018

Polycomb silencers control cell fate, development and cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058354

7 July 2018

Implication of abnormal epigenetic patterns for human diseases

1 reference

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7 July 2018

Model-based analysis of tiling-arrays for ChIP-chip.

1 reference

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7 July 2018

Genome-wide mapping of Polycomb target genes unravels their roles in cell fate transitions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058354

7 July 2018

Sex-determining region Y box 4 is a transforming oncogene in human prostate cancer cells

1 reference

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7 July 2018

Aberrant methylation and deacetylation of deleted in liver cancer-1 gene in prostate cancer: potential clinical applications

1 reference

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The retinoic acid synthesis gene ALDH1a2 is a candidate tumor suppressor in prostate cancer

1 reference

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Molecular profiling of human prostate tissues: insights into gene expression patterns of prostate development during puberty.

1 reference

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Gene expression profiling identifies clinically relevant subtypes of prostate cancer

1 reference

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Clustering of hypermethylated genes in neuroblastoma

1 reference

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Transcriptional silencing of zinc finger protein 185 identified by expression profiling is associated with prostate cancer progression

1 reference

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DNA hypermethylation is a mechanism for loss of expression of the HLA class I genes in human esophageal squamous cell carcinomas

1 reference

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Delineation of prognostic biomarkers in prostate cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058354

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The TES gene at 7q31.1 is methylated in tumours and encodes a novel growth-suppressing LIM domain protein

1 reference

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7 July 2018

Aberrant patterns of DNA methylation, chromatin formation and gene expression in cancer

1 reference

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Characterization of the human TESTIN gene localized in the FRA7G region at 7q31.2

1 reference

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Methylation-induced repression--belts, braces, and chromatin

1 reference

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Cancer epigenetics comes of age

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Genetic alterations in untreated metastases and androgen-independent prostate cancer detected by comparative genomic hybridization and allelotyping

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High sensitivity mapping of methylated cytosines

1 reference

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High promoter methylation levels of APC predict poor prognosis in sextant biopsies from prostate cancer patients.

1 reference

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1 reference

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Epigenetic remodeling in colorectal cancer results in coordinate gene suppression across an entire chromosome band.

1 reference

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DNA motifs associated with aberrant CpG island methylation.

1 reference

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Gene expression alterations in prostate cancer predicting tumor aggression and preceding development of malignancy.

1 reference

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Extensive analysis of the 7q31 region in human prostate tumors supports TES as the best candidate tumor suppressor gene.

1 reference

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Aberrant promoter methylation of the transcription factor genes PAX5 alpha and beta in human cancers.

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Genome-wide detection of LOH in prostate cancer using human SNP microarray technology

1 reference

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26 October 2018

Hypermethylation trigger of the glutathione-S-transferase gene (GSTP1) in prostate cancer cells.

1 reference

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Analysis of gene expression identifies candidate markers and pharmacological targets in prostate cancer

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Human prostate cancer and benign prostatic hyperplasia: molecular dissection by gene expression profiling

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26 October 2018

Loss of heterozygosity at 7q31 is a frequent and early event in prostate cancer

1 reference

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Gene expression correlates of clinical prostate cancer behavior

1 reference

https://pubmed.ncbi.nlm.nih.gov/20173741

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epigenetics and cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/20173741

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Distinctive nuclear organisation of centromeres and regions involved in pluripotency in human embryonic stem cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/20173741

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A broad band of silence

1 reference

https://pubmed.ncbi.nlm.nih.gov/20173741

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1038/NCB2023

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

Dimensions Publication ID

0 references

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

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