(Q34681437)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21357741%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

title

Liver-expressed Igkappa superantigen induces tolerance of polyclonal B cells by clonal deletion not kappa to lambda receptor editing (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21357741%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

1 reference

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21357741%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

author name string

Takayuki Ota

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21357741%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

Miyo Ota

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21357741%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

Bao Hoa Duong

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21357741%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

Amanda L Gavin

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21357741%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

language of work or name

English

0 references

publication date

28 February 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21357741%20AND%20SRC:MED&resulttype=core&format=json

Journal of Experimental Medicine

23 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21357741%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

volume

208

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21357741%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

issue

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21357741%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

page(s)

617-629

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21357741%20AND%20SRC:MED&resulttype=core&format=json

Antigen-presenting cell function in the tolerogenic liver environment.

23 January 2020

cites work

1 reference

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Regulation of the B cell receptor repertoire and self-reactivity by BAFF

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058582

AAV vectors avoid inflammatory signals necessary to render transduced hepatocyte targets for destructive T cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058582

Peripheral B cell tolerance and function in transgenic mice expressing an IgD superantigen.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058582

7 July 2018

Cracking the BAFF code.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058582

Suppression of IgE B cells and IgE binding to Fc(epsilon)RI by gene therapy with single-chain anti-IgE.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058582

B-cell anergy: from transgenic models to naturally occurring anergic B cells?

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058582

Cutting edge: inherent and acquired resistance to radiation-induced apoptosis in B cells: a pivotal role for STAT3.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058582

Naive CD4 T cells constitutively express CD40L and augment autoreactive B cell survival

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058582

deltaBAFF, a splice isoform of BAFF, opposes full-length BAFF activity in vivo in transgenic mouse models

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058582

An immunoglobulin C kappa-reactive single chain antibody fusion protein induces tolerance through receptor editing in a normal polyclonal immune system

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058582

Receptor editing in peripheral B cell tolerance

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058582

Staphylococcal toxin induced preferential and prolonged in vivo deletion of innate-like B lymphocytes.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058582

Human autoantibody silencing by immunoglobulin light chains

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058582

Receptor editing is the main mechanism of B cell tolerance toward membrane antigens

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058582

Predominant autoantibody production by early human B cell precursors

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058582

Expression of a targeted lambda 1 light chain gene is developmentally regulated and independent of Ig kappa rearrangements

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058582

B cell anergy and systemic lupus erythematosus

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058582

Balanced responsiveness to chemoattractants from adjacent zones determines B-cell position

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058582

CD23 defines two distinct subsets of immature B cells which differ in their responses to T cell help signals.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058582

Association of BAFF/BLyS overexpression and altered B cell differentiation with Sjögren's syndrome

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058582

Elevated serum B lymphocyte stimulator levels in patients with systemic immune-based rheumatic diseases.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058582

Anergy and not clonal ignorance determines the fate of B cells that recognize a physiological autoantigen

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058582

Activation and anergy in bone marrow B cells of a novel immunoglobulin transgenic mouse that is both hapten specific and autoreactive.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058582

Cutting edge: a role for B lymphocyte stimulator in systemic lupus erythematosus

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058582

Revising B cell receptors

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058582

T cell-independent rescue of B lymphocytes from peripheral immune tolerance

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058582

B cell clonal elimination induced by membrane-bound self-antigen may require repeated antigen encounter or cell competition

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058582

Mice transgenic for BAFF develop lymphocytic disorders along with autoimmune manifestations

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058582

High levels of foreign gene expression in hepatocytes after tail vein injections of naked plasmid DNA.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058582

Dual roles for glucokinase in glucose homeostasis as determined by liver and pancreatic beta cell-specific gene knock-outs using Cre recombinase

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058582

Rapid elimination of mature autoreactive B cells demonstrated by Cre-induced change in B cell antigen receptor specificity in vivo

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058582

Receptor editing occurs frequently during normal B cell development.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058582

Efficient peripheral clonal elimination of B lymphocytes in MRL/lpr mice bearing autoantibody transgenes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058582

Polygenic autoimmune traits: Lyn, CD22, and SHP-1 are limiting elements of a biochemical pathway regulating BCR signaling and selection

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058582

Self-reactive B cells are not eliminated or inactivated by autoantigen expressed on thyroid epithelial cells.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058582

Enforced Bcl-2 expression inhibits antigen-mediated clonal elimination of peripheral B cells in an antigen dose-dependent manner and promotes receptor editing in autoreactive, immature B cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058582

Different nuclear signals are activated by the B cell receptor during positive versus negative signaling.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058582

Expansion or elimination of B cells in vivo: dual roles for CD40- and Fas (CD95)-ligands modulated by the B cell antigen receptor.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058582

The fate of self-reactive B cells depends primarily on the degree of antigen receptor engagement and availability of T cell help.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058582

Receptor editing: an approach by autoreactive B cells to escape tolerance

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058582

Receptor editing in self-reactive bone marrow B cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058582

Peripheral B cell maturation. II. Heat-stable antigen(hi) splenic B cells are an immature developmental intermediate in the production of long-lived marrow-derived B cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058582

Cross-linking of membrane immunoglobulin D, in the absence of T cell help, kills mature B cells in vivo

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058582

Transitional B cells are the target of negative selection in the B cell compartment

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058582

Light chain replacement: a new model for antibody gene rearrangement

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058582

Competition for follicular niches excludes self-reactive cells from the recirculating B-cell repertoire.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058582

The autoantigen-binding B cell repertoires of normal and of chronically graft-versus-host-diseased mice

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058582

Altered immunoglobulin expression and functional silencing of self-reactive B lymphocytes in transgenic mice.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058582

Preferential autoantibody reactivity of the preimmune B cell repertoire in normal mice

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058582

Lack of feedback inhibition of V kappa gene rearrangement by productively rearranged alleles

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058582

Peripheral deletion of self-reactive B cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058582

Ig repertoire of human polyspecific antibodies and B cell ontogeny

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058582

Mutations in T-cell antigen receptor genes alpha and beta block thymocyte development at different stages

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058582

Resolution of three nonproliferative immature splenic B cell subsets reveals multiple selection points during peripheral B cell maturation

7 July 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20102265

Reduced life span of anergic self-reactive B cells in a double-transgenic model

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20102265

Breakdown of self-tolerance in anergic B lymphocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20102265

Oscillating CD8(+) T cell effector functions after antigen recognition in the liver.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20102265

Reduced competitiveness of autoantigen-engaged B cells due to increased dependence on BAFF.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20102265

Hydrodynamics-based transfection in animals by systemic administration of plasmid DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20102265

Identification of anergic B cells within a wild-type repertoire.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20102265

CD95 (Fas)-dependent elimination of self-reactive B cells upon interaction with CD4+ T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20102265

Transitional B lymphocyte subsets operate as distinct checkpoints in murine splenic B cell development

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20102265

Excess BAFF rescues self-reactive B cells from peripheral deletion and allows them to enter forbidden follicular and marginal zone niches.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20102265

Contribution of Receptor Editing to the Antibody Repertoire

21 January 2018

2 references

https://api.crossref.org/works/10.1084%2FJEM.20102265

21 January 2018

12 December 2020

Association of BAFF/BLyS overexpression and altered B cell differentiation with Sjögren’s syndrome

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20102265

Antigen-induced apoptotic death of Ly-1 B cells responsible for autoimmune disease in transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20102265

Continued RAG expression in late stages of B cell development and no apparent re-induction after immunizion

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20102265

Peripheral lymphoid development and function in TCR mutant mice

21 January 2018

1 reference

12 December 2020

Maternal Ig mediates neonatal tolerance in rheumatoid factor transgenic mice but tolerance breaks down in adult mice

1 reference

12 December 2020

Characterization of immature B cells by a novel monoclonal antibody, by turnover and by mitogen reactivity.

1 reference

12 December 2020

Negative selection of immature B cells by receptor editing or deletion is determined by site of antigen encounter

1 reference

12 December 2020

Positive selection of natural autoreactive B cells

1 reference

12 December 2020

Maintenance of B cell anergy requires constant antigen receptor occupancy and signaling

1 reference

12 December 2020

Antigen receptor editing in anti-DNA transitional B cells deficient for surface IgM

1 reference

12 December 2020

In vivo assessment of the relative contributions of deletion, anergy, and editing to B cell self-tolerance

1 reference

12 December 2020

Regulation of immunoglobulin light chain gene rearrangements during early B cell development in the human

1 reference

12 December 2020

Murine hybridomas secreting natural monoclonal antibodies reacting with self antigens

1 reference

12 December 2020

Antigen-receptor cross-linking induces peritoneal B-cell apoptosis in normal but not autoimmunity-prone mice

1 reference

12 December 2020

Identifiers

DOI

10.1084/JEM.20102265

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21357741%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21357741%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

1 reference