Home
Random
Nearby
Log in
Settings
Donate
About Wikidata
Disclaimers
Search
(Q34685494)
Watch
English
The Gli code: an information nexus regulating cell fate, stemness and cancer.
scientific article
In more languages
default values for all languages
No label defined
No description defined
edit
Statements
instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PMC publication ID
2601665
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17845852%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 January 2020
review article
1 reference
stated in
Europe PubMed Central
title
The Gli code: an information nexus regulating cell fate, stemness and cancer
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
2601665
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17845852%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 January 2020
author
Christophe Mas
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMC publication ID
2601665
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17845852%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 January 2020
Barbara Stecca
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMC publication ID
2601665
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17845852%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 January 2020
author name string
Ariel Ruiz i Altaba
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
2601665
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17845852%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 January 2020
publication date
12 September 2007
1 reference
stated in
Europe PubMed Central
PMC publication ID
2601665
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17845852%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 January 2020
published in
Trends in Cell Biology
1 reference
stated in
Europe PubMed Central
PMC publication ID
2601665
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17845852%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 January 2020
volume
17
1 reference
stated in
Europe PubMed Central
PMC publication ID
2601665
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17845852%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 January 2020
issue
9
1 reference
stated in
Europe PubMed Central
PMC publication ID
2601665
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17845852%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 January 2020
page(s)
438-447
1 reference
stated in
Europe PubMed Central
PMC publication ID
2601665
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17845852%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 January 2020
cites work
Patched1 regulates hedgehog signaling at the primary cilium
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2601665
retrieved
7 July 2018
Essential role of stromally induced hedgehog signaling in B-cell malignancies
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2601665
retrieved
7 July 2018
Inhibition of GLI-mediated transcription and tumor cell growth by small-molecule antagonists
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2601665
retrieved
7 July 2018
Genomic characterization of Gli-activator targets in sonic hedgehog-mediated neural patterning
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2601665
retrieved
7 July 2018
Melanomas require HEDGEHOG-GLI signaling regulated by interactions between GLI1 and the RAS-MEK/AKT pathways.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2601665
retrieved
7 July 2018
Hedgehog signaling maintains a tumor stem cell compartment in multiple myeloma
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2601665
retrieved
7 July 2018
Blockade of hedgehog signaling inhibits pancreatic cancer invasion and metastases: a new paradigm for combination therapy in solid cancers
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2601665
retrieved
7 July 2018
Inhibitory Gli3 activity negatively regulates Wnt/beta-catenin signaling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2601665
retrieved
7 July 2018
Phorbol esters inhibit the Hedgehog signalling pathway downstream of Suppressor of Fused, but upstream of Gli.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2601665
retrieved
7 July 2018
Identification of pancreatic cancer stem cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2601665
retrieved
7 July 2018
A novel protein-processing domain in Gli2 and Gli3 differentially blocks complete protein degradation by the proteasome
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2601665
retrieved
7 July 2018
HEDGEHOG-GLI1 signaling regulates human glioma growth, cancer stem cell self-renewal, and tumorigenicity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2601665
retrieved
7 July 2018
Wnt and Hedgehog are critical mediators of cigarette smoke-induced lung cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2601665
retrieved
7 July 2018
Sonic hedgehog signaling in forebrain development and its interactions with pathways that modify its effects
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2601665
retrieved
7 July 2018
Hedgehog modulates cell cycle regulators in stem cells to control hematopoietic regeneration
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2601665
retrieved
7 July 2018
Selective modulation of Hedgehog/GLI target gene expression by epidermal growth factor signaling in human keratinocytes.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2601665
retrieved
7 July 2018
Hedgehog signaling and Bmi-1 regulate self-renewal of normal and malignant human mammary stem cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2601665
retrieved
7 July 2018
The chicken talpid3 gene encodes a novel protein essential for Hedgehog signaling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2601665
retrieved
7 July 2018
Phosphoinositide 3-kinase and Akt are essential for Sonic Hedgehog signaling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2601665
retrieved
7 July 2018
Genetic elimination of Suppressor of fused reveals an essential repressor function in the mammalian Hedgehog signaling pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2601665
retrieved
7 July 2018
Protein kinase C-delta and mitogen-activated protein/extracellular signal-regulated kinase-1 control GLI activation in hedgehog signaling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2601665
retrieved
7 July 2018
Dual degradation signals control Gli protein stability and tumor formation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2601665
retrieved
7 July 2018
Complementary Gli activity mediates early patterning of the mouse visual system
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2601665
retrieved
7 July 2018
Prospective identification of tumorigenic prostate cancer stem cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2601665
retrieved
7 July 2018
Gli2 and Gli3 localize to cilia and require the intraflagellar transport protein polaris for processing and function
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2601665
retrieved
7 July 2018
A tumorigenic subpopulation with stem cell properties in melanomas
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2601665
retrieved
7 July 2018
In vivo analysis of quiescent adult neural stem cells responding to Sonic hedgehog
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2601665
retrieved
7 July 2018
Snail induction is an early response to Gli1 that determines the efficiency of epithelial transformation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2601665
retrieved
7 July 2018
Neural stem cells and the origin of gliomas
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2601665
retrieved
7 July 2018
Cooperative requirement of the Gli proteins in neurogenesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2601665
retrieved
7 July 2018
A gradient of Gli activity mediates graded Sonic Hedgehog signaling in the neural tube
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2601665
retrieved
7 July 2018
In vivo inhibition of endogenous brain tumors through systemic interference of Hedgehog signaling in mice.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2601665
retrieved
7 July 2018
Zebrafish Gli3 functions as both an activator and a repressor in Hedgehog signaling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2601665
retrieved
7 July 2018
Sonic hedgehog controls stem cell behavior in the postnatal and adult brain
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2601665
retrieved
7 July 2018
Unexpected Hedgehog-Wnt interactions in epithelial differentiation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2601665
retrieved
7 July 2018
Identification of human brain tumour initiating cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2601665
retrieved
7 July 2018
MIM/BEG4, a Sonic hedgehog-responsive gene that potentiates Gli-dependent transcription
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2601665
retrieved
7 July 2018
Activation of the BCL2 promoter in response to Hedgehog/GLI signal transduction is predominantly mediated by GLI2
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2601665
retrieved
7 July 2018
Hedgehog signalling in prostate regeneration, neoplasia and metastasis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2601665
retrieved
7 July 2018
Sonic hedgehog-patched Gli signaling in the developing rat prostate gland: lobe-specific suppression by neonatal estrogens reduces ductal growth and branching
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2601665
retrieved
7 July 2018
Inhibition of prostate cancer proliferation by interference with SONIC HEDGEHOG-GLI1 signaling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2601665
retrieved
7 July 2018
REN(KCTD11) is a suppressor of Hedgehog signaling and is deleted in human medulloblastoma
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2601665
retrieved
7 July 2018
Transduction of graded Hedgehog signaling by a combination of Gli2 and Gli3 activator functions in the developing spinal cord
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2601665
retrieved
7 July 2018
Bmi1 is essential for cerebellar development and is overexpressed in human medulloblastomas
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2601665
retrieved
7 July 2018
All mouse ventral spinal cord patterning by hedgehog is Gli dependent and involves an activator function of Gli3
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2601665
retrieved
7 July 2018
The emergent design of the neural tube: prepattern, SHH morphogen and GLI code
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2601665
retrieved
7 July 2018
Hedgehog is an early and late mediator of pancreatic cancer tumorigenesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2601665
retrieved
7 July 2018
Hedgehog signalling within airway epithelial progenitors and in small-cell lung cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2601665
retrieved
7 July 2018
Sonic hedgehog regulates adult neural progenitor proliferation in vitro and in vivo
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2601665
retrieved
7 July 2018
Small-molecule modulators of Hedgehog signaling: identification and characterization of Smoothened agonists and antagonists
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2601665
retrieved
7 July 2018
Dorsal-ventral patterning of the spinal cord requires Gli3 transcriptional repressor activity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2601665
retrieved
7 July 2018
Small molecule modulation of Smoothened activity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2601665
retrieved
7 July 2018
Human cortical glial tumors contain neural stem-like cells expressing astroglial and neuronal markers in vitro
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2601665
retrieved
7 July 2018
Shh and Gli3 are dispensable for limb skeleton formation but regulate digit number and identity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2601665
retrieved
7 July 2018
Regulation of Gli1 transcriptional activity in the nucleus by Dyrk1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2601665
retrieved
7 July 2018
The Sonic Hedgehog-Gli pathway regulates dorsal brain growth and tumorigenesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2601665
retrieved
7 July 2018
Gene expression profiling leads to identification of GLI1-binding elements in target genes and a role for multiple downstream pathways in GLI1-induced cell transformation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2601665
retrieved
7 July 2018
Physical and functional interactions between Zic and Gli proteins
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2601665
retrieved
7 July 2018
Specification of ventral neuron types is mediated by an antagonistic interaction between Shh and Gli3
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2601665
retrieved
7 July 2018
Gli2 functions in FGF signaling during antero-posterior patterning
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2601665
retrieved
7 July 2018
Expression of the vertebrate Gli proteins in Drosophila reveals a distribution of activator and repressor activities.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2601665
retrieved
7 July 2018
Combined activation of Ras and Akt in neural progenitors induces glioblastoma formation in mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2601665
retrieved
7 July 2018
Induction of basal cell carcinomas and trichoepitheliomas in mice overexpressing GLI-1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2601665
retrieved
7 July 2018
The transcription factor snail is a repressor of E-cadherin gene expression in epithelial tumour cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2601665
retrieved
7 July 2018
The transcription factor snail controls epithelial-mesenchymal transitions by repressing E-cadherin expression
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2601665
retrieved
7 July 2018
Mammalian suppressor-of-fused modulates nuclear-cytoplasmic shuttling of Gli-1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2601665
retrieved
7 July 2018
Gli proteins encode context-dependent positive and negative functions: implications for development and disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2601665
retrieved
7 July 2018
Sonic hedgehog regulates the growth and patterning of the cerebellum
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2601665
retrieved
7 July 2018
Purkinje-cell-derived Sonic hedgehog regulates granule neuron precursor cell proliferation in the developing mouse cerebellum
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2601665
retrieved
7 July 2018
Control of neuronal precursor proliferation in the cerebellum by Sonic Hedgehog
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2601665
retrieved
7 July 2018
Rhabdomyosarcomas and radiation hypersensitivity in a mouse model of Gorlin syndrome
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2601665
retrieved
7 July 2018
Combinatorial Gli gene function in floor plate and neuronal inductions by Sonic hedgehog
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2601665
retrieved
7 July 2018
Activation of the transcription factor Gli1 and the Sonic hedgehog signalling pathway in skin tumours
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2601665
retrieved
7 July 2018
Altered neural cell fates and medulloblastoma in mouse patched mutants
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2601665
retrieved
7 July 2018
Catching a Gli-mpse of Hedgehog
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2601665
retrieved
7 July 2018
Gli1 is a target of Sonic hedgehog that induces ventral neural tube development
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2601665
retrieved
7 July 2018
Proteolysis that is inhibited by hedgehog targets Cubitus interruptus protein to the nucleus and converts it to a repressor
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2601665
retrieved
7 July 2018
Cyclopia and defective axial patterning in mice lacking Sonic hedgehog gene function
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2601665
retrieved
7 July 2018
A search for gli expression in tumors of the central nervous system
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2601665
retrieved
7 July 2018
Identification of an amplified, highly expressed gene in a human glioma
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2601665
retrieved
7 July 2018
Oncogenic KRAS activates hedgehog signaling pathway in pancreatic cancer cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2601665
retrieved
26 October 2018
Multiple ubiquitin-dependent processing pathways regulate hedgehog/gli signaling: implications for cell development and tumorigenesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2601665
retrieved
26 October 2018
A negative feedback signaling network underlies oncogene-induced senescence
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2601665
retrieved
26 October 2018
Numb is a suppressor of Hedgehog signalling and targets Gli1 for Itch-dependent ubiquitination
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2601665
retrieved
26 October 2018
Cytotoxic effects induced by a combination of cyclopamine and gefitinib, the selective hedgehog and epidermal growth factor receptor signaling inhibitors, in prostate cancer cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2601665
retrieved
26 October 2018
Suppression of the Shh pathway using a small molecule inhibitor eliminates medulloblastoma in Ptc1(+/-)p53(-/-) mice.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2601665
retrieved
26 October 2018
Hedgehog--Gli signaling in brain tumors: stem cells and paradevelopmental programs in cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2601665
retrieved
26 October 2018
Hedgehog-GLI signaling regulates the behavior of cells with stem cell properties in the developing neocortex.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2601665
retrieved
26 October 2018
Sonic hedgehog is required for progenitor cell maintenance in telencephalic stem cell niches.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2601665
retrieved
26 October 2018
The amino-terminal region of Gli3 antagonizes the Shh response and acts in dorsoventral fate specification in the developing spinal cord.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2601665
retrieved
26 October 2018
Nmyc upregulation by sonic hedgehog signaling promotes proliferation in developing cerebellar granule neuron precursors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2601665
retrieved
26 October 2018
Medulloblastoma growth inhibition by hedgehog pathway blockade
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2601665
retrieved
26 October 2018
Wnt signals are targets and mediators of Gli function.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2601665
retrieved
26 October 2018
Patched target Igf2 is indispensable for the formation of medulloblastoma and rhabdomyosarcoma.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2601665
retrieved
26 October 2018
The repressor and activator forms of Cubitus interruptus control Hedgehog target genes through common generic gli-binding sites.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2601665
retrieved
26 October 2018
Hedgehog controls limb development by regulating the activities of distinct transcriptional activator and repressor forms of Cubitus interruptus.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2601665
retrieved
26 October 2018
Gli/Zic factors pattern the neural plate by defining domains of cell differentiation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2601665
retrieved
26 October 2018
Hedgehog activity, independent of decapentaplegic, participates in wing disc patterning.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2601665
retrieved
26 October 2018
Teratogenic compounds ofVeratrum californicum (Durand). X. Cyclopia in rabbits produced by cyclopamine
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/17845852
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
The Sonic hedgehog pathway independently controls the patterning, proliferation and survival of neuroepithelial cells by regulating Gli activity
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/17845852
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Carboxy-terminally truncated Gli3 proteins associate with Smads
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/17845852
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1016/J.TCB.2007.06.007
1 reference
stated in
Europe PubMed Central
PMC publication ID
2601665
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17845852%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 January 2020
PMC publication ID
2601665
1 reference
stated in
Europe PubMed Central
PMC publication ID
2601665
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17845852%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 January 2020
PubMed publication ID
17845852
1 reference
stated in
Europe PubMed Central
PMC publication ID
2601665
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17845852%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 January 2020
ResearchGate publication ID
5994371
0 references
Sitelinks
Wikipedia
(0 entries)
edit
Wikibooks
(0 entries)
edit
Wikinews
(0 entries)
edit
Wikiquote
(0 entries)
edit
Wikisource
(0 entries)
edit
Wikiversity
(0 entries)
edit
Wikivoyage
(0 entries)
edit
Wiktionary
(0 entries)
edit
Multilingual sites
(0 entries)
edit