(Q34686983)

3 August 2017

title

Differential regulation of BACE1 expression by oxidative and nitrosative signals (English)

1 reference

3 August 2017

Young-Don Kwak

1

1 reference

3 August 2017

Ruishan Wang

2

1 reference

3 August 2017

Jing Jing Li

3

1 reference

3 August 2017

Yun-Wu Zhang

4

1 reference

3 August 2017

Huaxi Xu

5

1 reference

3 August 2017

Francesca-Fang Liao

6

1 reference

3 August 2017

language of work or name

1 reference

3 March 2011

1 reference

Molecular Neurodegeneration

3 August 2017

published in

1 reference

3 August 2017

volume

6

1 reference

3 August 2017

page(s)

17

1 reference

Endothelial nitric oxide modulates expression and processing of amyloid precursor protein

3 August 2017

cites work

1 reference

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SCFFbx2-E3-ligase-mediated degradation of BACE1 attenuates Alzheimer's disease amyloidosis and improves synaptic function

7 July 2018

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The Rps23rg gene family originated through retroposition of the ribosomal protein s23 mRNA and encodes proteins that decrease Alzheimer's beta-amyloid level and tau phosphorylation

7 July 2018

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7 July 2018

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Redox reactions induced by nitrosative stress mediate protein misfolding and mitochondrial dysfunction in neurodegenerative diseases

7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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Oxidatively modified proteins in Alzheimer's disease (AD), mild cognitive impairment and animal models of AD: role of Abeta in pathogenesis

7 July 2018

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PGC-1alpha expression decreases in the Alzheimer disease brain as a function of dementia

7 July 2018

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Antidiabetic drug metformin (GlucophageR) increases biogenesis of Alzheimer's amyloid peptides via up-regulating BACE1 transcription.

7 July 2018

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The up-regulation of BACE1 mediated by hypoxia and ischemic injury: role of oxidative stress and HIF1alpha

7 July 2018

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7 July 2018

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Alzheimer disease Abeta production in the absence of S-palmitoylation-dependent targeting of BACE1 to lipid rafts

7 July 2018

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Cardiovascular risk factors and incident Alzheimer disease: a systematic review of the literature

7 July 2018

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Lipid peroxidation up-regulates BACE1 expression in vivo: a possible early event of amyloidogenesis in Alzheimer's disease

7 July 2018

1 reference

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Loss of microRNA cluster miR-29a/b-1 in sporadic Alzheimer's disease correlates with increased BACE1/beta-secretase expression

7 July 2018

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The expression of microRNA miR-107 decreases early in Alzheimer's disease and may accelerate disease progression through regulation of beta-site amyloid precursor protein-cleaving enzyme 1.

7 July 2018

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Molecular and cellular mechanisms for Alzheimer's disease: understanding APP metabolism

7 July 2018

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The Alzheimer's disease beta-secretase enzyme, BACE1.

7 July 2018

1 reference

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Oxidative DNA damage in mild cognitive impairment and late-stage Alzheimer's disease

7 July 2018

1 reference

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Depletion of GGA3 stabilizes BACE and enhances beta-secretase activity

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059281

Hypoxia-inducible factor 1alpha (HIF-1alpha)-mediated hypoxia increases BACE1 expression and beta-amyloid generation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059281

Hypoxia facilitates Alzheimer's disease pathogenesis by up-regulating BACE1 gene expression

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059281

Pathological and physiological functions of presenilins

7 July 2018

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Transcriptional and translational regulation of BACE1 expression--implications for Alzheimer's disease

7 July 2018

1 reference

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Nonsteroidal anti-inflammatory drugs repress beta-secretase gene promoter activity by the activation of PPARgamma

7 July 2018

1 reference

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Increased risk of Alzheimer's disease in Type II diabetes: insulin resistance of the brain or insulin-induced amyloid pathology?

7 July 2018

1 reference

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Metabolic control through the PGC-1 family of transcription coactivators

7 July 2018

1 reference

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Distinct transcriptional regulation and function of the human BACE2 and BACE1 genes

7 July 2018

1 reference

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Beta-site APP cleaving enzyme up-regulation induced by 4-hydroxynonenal is mediated by stress-activated protein kinases pathways.

7 July 2018

1 reference

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Degradation of BACE by the ubiquitin-proteasome pathway

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059281

Expression of the Alzheimer protease BACE1 is suppressed via its 5'-untranslated region

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059281

Functional characterization of the 5' flanking region of the BACE gene: identification of a 91 bp fragment involved in basal level of BACE promoter expression

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059281

Amyloid beta peptide load is correlated with increased beta-secretase activity in sporadic Alzheimer's disease patients

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059281

Transcriptional regulation of BACE1, the beta-amyloid precursor protein beta-secretase, by Sp1.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059281

Mitochondrial biogenesis in mammals: the role of endogenous nitric oxide.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059281

Redox regulatory and anti-apoptotic functions of thioredoxin depend on S-nitrosylation at cysteine 69.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059281

Aging and the role of reactive nitrogen species

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059281

The disulphide bonds in the catalytic domain of BACE are critical but not essential for amyloid precursor protein processing activity

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059281

BACE knockout mice are healthy despite lacking the primary beta-secretase activity in brain: implications for Alzheimer's disease therapeutics

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059281

Mice deficient in BACE1, the Alzheimer's beta-secretase, have normal phenotype and abolished beta-amyloid generation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059281

Effects of oxidative and nitrosative stress in cytotoxicity

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059281

Nitric oxide in neurodegeneration

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059281

(S)NO signals: translocation, regulation, and a consensus motif

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059281

Nitric oxide in the central nervous system.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059281

The emerging multifaceted roles of nitric oxide

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059281

Nitric oxide: a physiologic messenger molecule

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059281

Effect of nitric oxide production on the redox modulatory site of the NMDA receptor-channel complex

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059281

Increased risk of type 2 diabetes in Alzheimer disease

7 July 2018

1 reference

https://api.crossref.org/works/10.1186%2F1750-1326-6-17

Beta-secretase protein and activity are increased in the neocortex in Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1750-1326-6-17

alpha- and beta-secretase: profound changes in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1750-1326-6-17

Increased expression of the amyloid precursor beta-secretase in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1750-1326-6-17

Elevated beta-secretase expression and enzymatic activity detected in sporadic Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1750-1326-6-17

Experimental traumatic brain injury in rats stimulates the expression, production and activity of Alzheimer's disease beta-secretase (BACE-1).

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1750-1326-6-17

Increased beta-secretase activity and expression in rats following transient cerebral ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1750-1326-6-17

Oxidative stress increases expression and activity of BACE in NT2 neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1750-1326-6-17

The increased activity of BACE1 correlates with oxidative stress in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1750-1326-6-17

Oxidative stress potentiates BACE1 gene expression and Abeta generation

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1750-1326-6-17

The carboxyl-terminus of BACE contains a sorting signal that regulates BACE trafficking but not the formation of total A(beta).

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1750-1326-6-17

The biotin switch method for the detection of S-nitrosylated proteins

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3059281

Vascular risk factors and Alzheimer's disease

26 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21371311

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1186/1750-1326-6-17

1 reference

Dimensions Publication ID

3 August 2017

0 references

1 reference

3 August 2017

1 reference