(Q34687780)

2 July 2019

review article

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title

Quality control of gene expression in the nucleus (English)

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2 July 2019

0 references

N Custódio

1

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2 July 2019

M Carmo-Fonseca

series ordinal

2

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2 July 2019

publication date

1 July 2001

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2 July 2019

Journal of Cellular and Molecular Medicine

published in

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2 July 2019

volume

5

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2 July 2019

page(s)

267-275

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2 July 2019

issue

3

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2 July 2019

Connecting transcription to messenger RNA processing

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The protein Aly links pre-messenger-RNA splicing to nuclear export in metazoans

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Quality control of mRNA function

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Nonsense codons can reduce the abundance of nuclear mRNA without affecting the abundance of pre-mRNA or the half-life of cytoplasmic mRNA.

21 January 2018

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Nonsense but not missense mutations can decrease the abundance of nuclear mRNA for the mouse major urinary protein, while both types of mutations can facilitate exon skipping

21 January 2018

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Intron function in the nonsense-mediated decay of beta-globin mRNA: indications that pre-mRNA splicing in the nucleus can influence mRNA translation in the cytoplasm

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Pre-mRNA splicing imprints mRNA in the nucleus with a novel RNA-binding protein that persists in the cytoplasm

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The acute myeloid leukemia-associated protein, DEK, forms a splicing-dependent interaction with exon-product complexes

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Precursor RNAs harboring nonsense codons accumulate near the site of transcription.

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Proofreading and aminoacylation of tRNAs before export from the nucleus.

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Interaction of eukaryotic translation initiation factor 4G with the nuclear cap-binding complex provides a link between nuclear and cytoplasmic functions of the m(7) guanosine cap.

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Inefficient processing impairs release of RNA from the site of transcription

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The C-terminal domain of RNA polymerase II couples mRNA processing to transcription

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Transcriptional termination and coupled polyadenylation in vitro

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Multiple transcript cleavage precedes polymerase release in termination by RNA polymerase II

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Efficient 3'-end formation of human beta-globin mRNA in vivo requires sequences within the last intron but occurs independently of the splicing reaction

21 January 2018

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Review: movement of mRNA from transcription site to nuclear pores

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Transport of proteins and RNAs in and out of the nucleus

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mRNA quality control: Marking the message for life or death.

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REF, an evolutionary conserved family of hnRNP-like proteins, interacts with TAP/Mex67p and participates in mRNA nuclear export.

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The C-terminal domain of TAP interacts with the nuclear pore complex and promotes export of specific CTE-bearing RNA substrates

21 January 2018

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A block to mRNA nuclear export in S. cerevisiae leads to hyperadenylation of transcripts that accumulate at the site of transcription

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Tracking COL1A1 RNA in osteogenesis imperfecta. splice-defective transcripts initiate transport from the gene but are retained within the SC35 domain

21 January 2018

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Foci of trinucleotide repeat transcripts in nuclei of myotonic dystrophy cells and tissues

21 January 2018

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Expansion of a CUG trinucleotide repeat in the 3' untranslated region of myotonic dystrophy protein kinase transcripts results in nuclear retention of transcripts

21 January 2018

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Coupling of transcription and translation in Dictyostelium discoideum nuclei

21 January 2018

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12 December 2020

Terminal exon definition occurs cotranscriptionally and promotes termination of RNA polymerase II

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12 December 2020

RNA polymerase II targets pre-mRNA splicing factors to transcription sites in vivo

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12 December 2020

Cis and trans effects of the myotonic dystrophy (DM) mutation in a cell culture model

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12 December 2020

Intranuclear trafficking of messenger RNA.

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12 December 2020

Pre-mRNA splicing alters mRNP composition: evidence for stable association of proteins at exon-exon junctions

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12 December 2020

RNA polymerase II and the integration of nuclear events

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12 December 2020

Myotonic dystrophy in transgenic mice expressing an expanded CUG repeat

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12 December 2020

A mechanism for exon skipping caused by nonsense or missense mutations in BRCA1 and other genes

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12 December 2020

Coupled transcription and translation within nuclei of mammalian cells.

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12 December 2020

Biomedicine. Reconstructing myotonic dystrophy

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12 December 2020

Immunofluorescence studies of human fibroblasts demonstrate the presence of the complex of elongation factor-1 beta gamma delta in the endoplasmic reticulum

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12 December 2020

A splicing-dependent regulatory mechanism that detects translation signals

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12 December 2020

Transcriptional termination in the Balbiani ring 1 gene is closely coupled to 3'-end formation and excision of the 3'-terminal intron

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12 December 2020

10.1111/J.1582-4934.2001.TB00160.X

Identifiers

DOI

1 reference

2 July 2019

PMCID

6514772

1 reference

2 July 2019

PubMed ID

12067485

1 reference

2 July 2019