(Q34693888)

4 August 2017

title

The deficiency of Akt1 is sufficient to suppress tumor development in Pten+/- mice (English)

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4 August 2017

8

Pier Paolo Pandolfi

0 references

author name string

Mei-Ling Chen

1

1 reference

4 August 2017

Pei-Zhang Xu

2

1 reference

4 August 2017

Xiao-ding Peng

3

1 reference

4 August 2017

William S Chen

4

1 reference

4 August 2017

Grace Guzman

5

1 reference

4 August 2017

Ximing Yang

6

1 reference

4 August 2017

Antonio Di Cristofano

7

1 reference

4 August 2017

Nissim Hay

9

1 reference

4 August 2017

publication date

1 June 2006

1 reference

4 August 2017

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4 August 2017

volume

20

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4 August 2017

issue

12

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4 August 2017

page(s)

1569-1574

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The Akt-mTOR tango and its relevance to cancer

4 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1482477

Phosphoinositide 3-kinase in disease: timing, location, and scaffolding

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1482477

Allosteric Akt (PKB) inhibitors: discovery and SAR of isozyme selective inhibitors

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1482477

The biology and clinical relevance of the PTEN tumor suppressor pathway

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1482477

Focus on endometrial and cervical cancer

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1482477

Prostate pathology of genetically engineered mice: definitions and classification. The consensus report from the Bar Harbor meeting of the Mouse Models of Human Cancer Consortium Prostate Pathology Committee.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1482477

Molecular determinants of resistance to antiandrogen therapy

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1482477

Dwarfism, impaired skin development, skeletal muscle atrophy, delayed bone development, and impeded adipogenesis in mice lacking Akt1 and Akt2.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1482477

Prostatic intraepithelial neoplasia in genetically engineered mice

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1482477

The phosphoinositide 3-kinase pathway

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1482477

Ten years of protein kinase B signalling: a hard Akt to follow

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1482477

Growth retardation and increased apoptosis in mice with homozygous disruption of the Akt1 gene

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1482477

The regulation and activities of the multifunctional serine/threonine kinase Akt/PKB.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1482477

Mutation of Pten/Mmac1 in mice causes neoplasia in multiple organ systems

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1482477

Pten is essential for embryonic development and tumour suppression

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1482477

Tumor cell sensitization to apoptotic stimuli by selective inhibition of specific Akt/PKB family members

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1482477

High cancer susceptibility and embryonic lethality associated with mutation of the PTEN tumor suppressor gene in mice

26 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16778075

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1101/GAD.1395006

1 reference

4 August 2017

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4 August 2017

1 reference