(Q34693980)

4 August 2017

The serine-threonine kinase LKB1 is essential for survival under energetic stress in zebrafish (English)

1 reference

4 August 2017

0 references

7

Hans Clevers

1 reference

4 August 2017

Yme U van der Velden

1

1 reference

4 August 2017

Liqin Wang

2

1 reference

4 August 2017

John Zevenhoven

3

1 reference

4 August 2017

Ellen van Rooijen

4

1 reference

4 August 2017

Maarten van Lohuizen

5

1 reference

4 August 2017

Rachel H Giles

6

1 reference

4 August 2017

Anna-Pavlina G Haramis

8

1 reference

4 August 2017

language of work or name

English

0 references

publication date

1 March 2011

1 reference

Proceedings of the National Academy of Sciences of the United States of America

4 August 2017

1 reference

4 August 2017

108

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4 August 2017

11

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4 August 2017

4358-4363

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Lkb1 regulates quiescence and metabolic homeostasis of haematopoietic stem cells

4 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060253

The Lkb1 metabolic sensor maintains haematopoietic stem cell survival

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060253

Lkb1 regulates cell cycle and energy metabolism in haematopoietic stem cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060253

Dynamic Lkb1-TORC1 signaling as a possible mechanism for regulating the endoderm-intestine transition

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060253

Reduced levels of IGF-I mediate differential protection of normal and cancer cells in response to fasting and improve chemotherapeutic index

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060253

LKB1 regulates pancreatic beta cell size, polarity, and function

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060253

The LKB1-AMPK pathway: metabolism and growth control in tumour suppression

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060253

mTOR and HIF-1alpha-mediated tumor metabolism in an LKB1 mouse model of Peutz-Jeghers syndrome

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060253

The zebrafish embryo as a dynamic model of anoxia tolerance

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060253

Starvation-dependent differential stress resistance protects normal but not cancer cells against high-dose chemotherapy.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060253

Pancreatic LKB1 deletion leads to acinar polarity defects and cystic neoplasms

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060253

AMP-activated/SNF1 protein kinases: conserved guardians of cellular energy

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060253

LKB1 modulates lung cancer differentiation and metastasis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060253

LKB1 and AMPK maintain epithelial cell polarity under energetic stress

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060253

Target of rapamycin (TOR) signaling controls epithelial morphogenesis in the vertebrate intestine

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060253

TOR signaling in growth and metabolism

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060253

Balancing Akt with S6K: implications for both metabolic diseases and tumorigenesis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060253

Generalized intestinal polyposis and melanin spots of the oral mucosa, lips and digits; a syndrome of diagnostic significance

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060253

Complete polarization of single intestinal epithelial cells upon activation of LKB1 by STRAD.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060253

The tumor suppressor LKB1 kinase directly activates AMP-activated kinase and regulates apoptosis in response to energy stress

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060253

Efficient target-selected mutagenesis in zebrafish

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060253

Complexes between the LKB1 tumor suppressor, STRAD alpha/beta and MO25 alpha/beta are upstream kinases in the AMP-activated protein kinase cascade

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060253

A role for Drosophila LKB1 in anterior-posterior axis formation and epithelial polarity

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060253

TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060253

Establishing cell polarity in development

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060253

Vascular abnormalities and deregulation of VEGF in Lkb1-deficient mice

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060253

Nine novel germline mutations of STK11 in ten families with Peutz-Jeghers syndrome

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060253

A serine/threonine kinase gene defective in Peutz-Jeghers syndrome

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060253

Increased risk of cancer in the Peutz-Jeghers syndrome

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060253

Loss of Lkb1 provokes highly invasive endometrial adenocarcinomas.

7 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1010210108

Caenorhabditis elegans dauers need LKB1/AMPK to ration lipid reserves and ensure long-term survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1010210108

Positional cloning of heart and soul reveals multiple roles for PKC lambda in zebrafish organogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1010210108

A whole-animal microplate assay for metabolic rate using zebrafish

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1010210108

Zebrafish mutants in the von Hippel-Lindau tumor suppressor display a hypoxic response and recapitulate key aspects of Chuvash polycythemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1010210108

Mutations affecting development of zebrafish digestive organs.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060253

26 October 2018

Identifiers

DOI

10.1073/PNAS.1010210108

1 reference

4 August 2017

0 references

1 reference

4 August 2017

1 reference