(Q34707143)

4 August 2017

title

Therapeutic levels of fetal hemoglobin in erythroid progeny of β-thalassemic CD34+ cells after lentiviral vector-mediated gene transfer (English)

1 reference

4 August 2017

1

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4 August 2017

Phillip W Hargrove

2

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4 August 2017

Yoon-Sang Kim

3

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4 August 2017

Janice M Riberdy

4

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4 August 2017

Vijay G Sankaran

5

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4 August 2017

Eleni Papanikolaou

6

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4 August 2017

Maria Georgomanoli

7

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4 August 2017

Nicholas P Anagnou

8

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4 August 2017

Stuart H Orkin

9

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4 August 2017

Arthur W Nienhuis

10

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4 August 2017

Derek A Persons

11

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4 August 2017

language of work or name

English

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publication date

14 December 2010

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4 August 2017

number of pages

10

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inferred from page(s)

published in

Blood

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4 August 2017

volume

117

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4 August 2017

issue

10

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4 August 2017

page(s)

2817-2826

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Lentiviral vector gene therapy: effective and safe?

4 August 2017

cites work

1 reference

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7 July 2018

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A zinc-finger transcriptional activator designed to interact with the gamma-globin gene promoters enhances fetal hemoglobin production in primary human adult erythroblasts

7 July 2018

1 reference

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Gene therapy. Beta-thalassemia treatment succeeds, with a caveat

7 July 2018

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Amelioration of murine beta-thalassemia through drug selection of hematopoietic stem cells transduced with a lentiviral vector encoding both gamma-globin and the MGMT drug-resistance gene

7 July 2018

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Ineffective erythropoiesis and thalassemias

7 July 2018

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Optimized lentiviral vector design improves titer and transgene expression of vectors containing the chicken beta-globin locus HS4 insulator element

7 July 2018

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Human fetal hemoglobin expression is regulated by the developmental stage-specific repressor BCL11A.

7 July 2018

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Correction of murine sickle cell disease using gamma-globin lentiviral vectors to mediate high-level expression of fetal hemoglobin

7 July 2018

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7 July 2018

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In vivo selection of genetically modified erythroblastic progenitors leads to long-term correction of beta-thalassemia

7 July 2018

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7 July 2018

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Hematopoietic cell transplantation for thalassemia and sickle cell disease: past, present and future

7 July 2018

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Advances in the allogeneic transplantation for thalassemia

7 July 2018

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Lessons from Nature: microRNA-based shRNA libraries

7 July 2018

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7 July 2018

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High-level beta-globin expression and preferred intragenic integration after lentiviral transduction of human cord blood stem cells

7 July 2018

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Extended beta-globin locus control region elements promote consistent therapeutic expression of a gamma-globin lentiviral vector in murine beta-thalassemia

7 July 2018

1 reference

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Bcl11b is required for differentiation and survival of αβ T lymphocytes

7 July 2018

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Bcl11a is essential for normal lymphoid development

7 July 2018

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Permanent and panerythroid correction of murine beta thalassemia by multiple lentiviral integration in hematopoietic stem cells

7 July 2018

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Development of virus vectors for gene therapy of beta chain hemoglobinopathies: flanking with a chromatin insulator reduces gamma-globin gene silencing in vivo

7 July 2018

1 reference

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Correction of sickle cell disease in transgenic mouse models by gene therapy

7 July 2018

1 reference

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Phenotype-genotype relationships in monogenic disease: lessons from the thalassaemias.

7 July 2018

1 reference

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Therapeutic haemoglobin synthesis in beta-thalassaemic mice expressing lentivirus-encoded human beta-globin

7 July 2018

1 reference

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7 July 2018

The beta-thalassemias

1 reference

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Absence of haemoglobin A in an individual simultaneously heterozygous in the genes for hereditary persistence of foetal haemoglobin and beta-thalassemia

7 July 2018

1 reference

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Bone marrow transplantation in adults with thalassemia: Treatment and long-term follow-up

7 July 2018

1 reference

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Successful correction of the human beta-thalassemia major phenotype using a lentiviral vector

26 October 2018

1 reference

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Hereditary persistence of fetal hemoglobin: a study of 79 affected persons in 15 Negro families in Baltimore

26 October 2018

1 reference

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Correction of a mouse model of sickle cell disease: lentiviral/antisickling beta-globin gene transduction of unmobilized, purified hematopoietic stem cells

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3062294

Flow cytometric analysis of hydroxyurea effects on fetal hemoglobin production in cultures of beta-thalassemia erythroid precursors

26 October 2018

1 reference

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The degree of phenotypic correction of murine beta -thalassemia intermedia following lentiviral-mediated transfer of a human gamma-globin gene is influenced by chromosomal position effects and vector copy number

26 October 2018

1 reference

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In vitro mass production of human erythroid cells from the blood of normal donors and of thalassemic patients

26 October 2018

1 reference

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Functional requirements for phenotypic correction of murine beta-thalassemia: implications for human gene therapy

26 October 2018

1 reference

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Ineffective erythropoiesis in beta-thalassemia major is due to apoptosis at the polychromatophilic normoblast stage.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3062294

Comparison of the relative quantities of gamma-mRNAs and fetal hemoglobin in SS patients with different haplotypes.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3062294

Pathogenesis and treatment of sickle cell disease

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3062294

Regulation of the beta- and delta-hemoglobin genes. A family with hereditary persistent fetal hemoglobin and beta-thalassemia

26 October 2018

1 reference

12 December 2020

Isolation and transplantation of autologous peripheral CD34+ progenitor cells highly purified by magnetic-activated cell sorting

1 reference

12 December 2020

Two families showing interaction of haemoglobin C or thalassaemia with high foetal haemoglobin in adults

1 reference

12 December 2020

Globin Lentiviral Vector Insertions Can Perturb the Expression of Endogenous Genes in β-thalassemic Hematopoietic Cells

1 reference

12 December 2020

A correlation of erythrokinetics, ineffective erythropoiesis, and erythroid precursor apoptosis in thai patients with thalassemia

1 reference

12 December 2020

Comparison of various envelope proteins for their ability to pseudotype lentiviral vectors and transduce primitive hematopoietic cells from human blood

1 reference

12 December 2020

10.1182/BLOOD-2010-08-300723

Identifiers

DOI

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