(Q34710083)

4 August 2017

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title

Proteolysis, free radicals, and aging (English)

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4 August 2017

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3

Luke I Szweda

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4 August 2017

Pamela A Szweda

1

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4 August 2017

Bertrand Friguet

series ordinal

2

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4 August 2017

publication date

1 July 2002

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Free Radical Biology and Medicine

4 August 2017

published in

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4 August 2017

volume

33

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4 August 2017

issue

1

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4 August 2017

page(s)

29-36

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4 August 2017

cites work

When lysosomes get old.

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7 January 2021

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7 January 2021

Possible involvement of proteasome inhibition in aging: implications for oxidative stress.

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7 January 2021

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7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900837-7

7 January 2021

Age-dependent declines in proteasome activity in the heart

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https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900837-7

7 January 2021

Reversal of age-related increase in brain protein oxidation, decrease in enzyme activity, and loss in temporal and spatial memory by chronic administration of the spin-trapping compound N-tert-butyl-alpha-phenylnitrone.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900837-7

7 January 2021

Proteasome inactivation upon aging and on oxidation-effect of HSP 90

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https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900837-7

7 January 2021

The proteasome, a novel protease regulated by multiple mechanisms

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900837-7

7 January 2021

Protein oxidation and 20S proteasome-dependent proteolysis in mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900837-7

7 January 2021

Degradation of oxidized proteins by the 20S proteasome.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900837-7

7 January 2021

Structure and functions of the 20S and 26S proteasomes

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https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900837-7

7 January 2021

The ubiquitin conjugation system is required for ligand-induced endocytosis and degradation of the growth hormone receptor.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900837-7

7 January 2021

Ubiquitin Sorts Proteins into the Intralumenal Degradative Compartment of the Late-Endosome/Vacuole

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https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900837-7

7 January 2021

Degradation of CFTR by the ubiquitin-proteasome pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900837-7

7 January 2021

ER degradation of a misfolded luminal protein by the cytosolic ubiquitin-proteasome pathway

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https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900837-7

7 January 2021

Stimulation-dependent I kappa B alpha phosphorylation marks the NF-kappa B inhibitor for degradation via the ubiquitin-proteasome pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900837-7

7 January 2021

IkappaB is a substrate for a selective pathway of lysosomal proteolysis

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https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900837-7

7 January 2021

Phosphorylation of human I kappa B-alpha on serines 32 and 36 controls I kappa B-alpha proteolysis and NF-kappa B activation in response to diverse stimuli

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900837-7

7 January 2021

Relocalization of cathepsin D and cytochrome c early in apoptosis revealed by immunoelectron microscopy

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https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900837-7

7 January 2021

Age-related Macular Degeneration

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7 January 2021

Ubiquitin-mediated degradation of the proapoptotic active form of bid. A functional consequence on apoptosis induction

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https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900837-7

7 January 2021

Bax degradation by the ubiquitin/proteasome-dependent pathway: involvement in tumor survival and progression

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https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900837-7

7 January 2021

Organelle-specific initiation of cell death pathways

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https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900837-7

7 January 2021

The endosomal-lysosomal system of neurons in Alzheimer's disease pathogenesis: a review

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https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900837-7

7 January 2021

The glial glutamate transporter, GLT-1, is oxidatively modified by 4-hydroxy-2-nonenal in the Alzheimer's disease brain: the role of Abeta1-42.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900837-7

7 January 2021

Vulnerability of synaptosomes from apoE knock-out mice to structural and oxidative modifications induced by A beta(1-40): implications for Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900837-7

7 January 2021

Immunohistochemical colocalization of glycoxidation products and lipid peroxidation products in diabetic renal glomerular lesions. Implication for glycoxidative stress in the pathogenesis of diabetic nephropathy

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900837-7

7 January 2021

Dysfunction of the islet lysosomal system conveys impairment of glucose-induced insulin release in the diabetic GK rat.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900837-7

7 January 2021

Inactivation of lysosomal proteases by oxidized low density lipoprotein is partially responsible for its poor degradation by mouse peritoneal macrophages

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900837-7

7 January 2021

Oxidative modification and inactivation of the proteasome during coronary occlusion/reperfusion

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900837-7

7 January 2021

Oxidative stress-associated impairment of proteasome activity during ischemia-reperfusion injury

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900837-7

7 January 2021

Protein oxidation in aging, disease, and oxidative stress

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900837-7

7 January 2021

The free radical theory of aging matures

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900837-7

7 January 2021

Caloric restriction of rhesus monkeys lowers oxidative damage in skeletal muscle

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900837-7

7 January 2021

Oxidative damage during aging targets mitochondrial aconitase

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900837-7

7 January 2021

Proteasome inhibition by lipofuscin/ceroid during postmitotic aging of fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900837-7

7 January 2021

Inhibition of the multicatalytic proteinase (proteasome) by 4-hydroxy-2-nonenal cross-linked protein

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900837-7

7 January 2021

Comparative resistance of the 20S and 26S proteasome to oxidative stress.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900837-7

7 January 2021

Differential impairment of 20S and 26S proteasome activities in human hematopoietic K562 cells during oxidative stress

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900837-7

7 January 2021

The effect of age on formation and elimination of autophagic vacuoles in mouse hepatocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900837-7

7 January 2021

Protein oxidation and degradation during cellular senescence of human BJ fibroblasts: part II—aging of nondividing cells

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900837-7

7 January 2021

Protein oxidation and degradation during cellular senescence of human BJ fibroblasts: part I--effects of proliferative senescence

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900837-7

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900837-7

7 January 2021

Evaluation of the activities of eight lysosomal hydrolases in sera of humans, rats and pigs of different ages

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900837-7

7 January 2021

Gene expression profile of aging and its retardation by caloric restriction

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900837-7

7 January 2021

Mitotic misregulation and human aging

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900837-7

7 January 2021

Studies on lipid peroxidation and protein oxidation in the aging brain

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900837-7

7 January 2021

Excess brain protein oxidation and enzyme dysfunction in normal aging and in Alzheimer disease

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900837-7

7 January 2021

Accumulation of Cardiac Lipofuscin Depends on Metabolic Rate of Mammals

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900837-7

7 January 2021

Accumulation of cardiac lipofuscin in crab-eating monkeys (Macaca fasicularis): the same rate of lipofuscin accumulation in several species of primates

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900837-7

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900837-7

7 January 2021

The canine as an animal model of human aging and dementia

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900837-7

7 January 2021

Ca2+-free calmodulin and calmodulin damaged by in vitro aging are selectively degraded by 26 S proteasomes without ubiquitination.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900837-7

7 January 2021

Recognition of misfolding proteins by PA700, the regulatory subcomplex of the 26 S proteasome

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900837-7

7 January 2021

Exposure of hydrophobic moieties promotes the selective degradation of hydrogen peroxide-modified hemoglobin by the multicatalytic proteinase complex, proteasome

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900837-7

7 January 2021

Susceptibility of glucose-6-phosphate dehydrogenase modified by 4-hydroxy-2-nonenal and metal-catalyzed oxidation to proteolysis by the multicatalytic protease.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900837-7

7 January 2021

On the degradability and exocytosis of ceroid/lipofuscin in cultured rat cardiac myocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900837-7

7 January 2021

4-Hydroxy-2-nonenal-mediated impairment of intracellular proteolysis during oxidative stress. Identification of proteasomes as target molecules

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900837-7

7 January 2021

Protein oxidation and enzyme activity decline in old brown Norway rats are reduced by dietary restriction.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900837-7

7 January 2021

Mechanisms of life span determination in Caenorhabditis elegans

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900837-7

7 January 2021

Dietary self-selection can compensate an age-related decrease of rat liver 20 S proteasome activity observed with standard diet

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900837-7

7 January 2021

The protection of rat liver autophagic proteolysis from the age-related decline co-varies with the duration of anti-ageing food restriction

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900837-7

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900837-7

7 January 2021

Gene expression and cellular content of cathepsin D in Alzheimer's disease brain: evidence for early up-regulation of the endosomal-lysosomal system.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900837-7

7 January 2021

Endocytic pathway abnormalities precede amyloid beta deposition in sporadic Alzheimer's disease and Down syndrome: differential effects of APOE genotype and presenilin mutations

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900837-7

7 January 2021

Role of the proteasome in Alzheimer’s disease

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900837-7

7 January 2021

Increased neuronal endocytosis and protease delivery to early endosomes in sporadic Alzheimer's disease: neuropathologic evidence for a mechanism of increased beta-amyloidogenesis.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900837-7

7 January 2021

Protein oxidation in the brain in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900837-7

7 January 2021

Oxidation of Abeta and plaque biogenesis in Alzheimer's disease and Down syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900837-7

7 January 2021

Four-hydroxynonenal, a product of lipid peroxidation, is increased in the brain in Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900837-7

7 January 2021

Ubiquitin is detected in neurofibrillary tangles and senile plaque neurites of Alzheimer disease brains

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900837-7

7 January 2021

Cardiac reperfusion injury: aging, lipid peroxidation, and mitochondrial dysfunction

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900837-7

7 January 2021

Declines in mitochondrial respiration during cardiac reperfusion: age-dependent inactivation of alpha-ketoglutarate dehydrogenase

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900837-7

7 January 2021

Increased left ventricular dysfunction in elderly patients despite successful thrombolysis: the GUSTO-I angiographic experience

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900837-7

7 January 2021

Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900837-7

7 January 2021

The proteasome activator 11 S REG (PA28) and class I antigen presentation

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900837-7

7 January 2021

Interferon regulatory factor 1 mediates the interferon-gamma induction of the human immunoproteasome subunit multicatalytic endopeptidase complex-like 1.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900837-7

7 January 2021

Ceroid/lipofuscin-loaded human fibroblasts show increased susceptibility to oxidative stress

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900837-7

7 January 2021

10.1016/S0891-5849(02)00837-7

Identifiers

DOI

1 reference

4 August 2017

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