(Q34714740)

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Alpha-synuclein aggregation induced by brief ischemia negatively impacts neuronal survival in vivo: a study in [A30P]alpha-synuclein transgenic mouse

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14 February 2020

Alpha-synuclein aggregation induced by brief ischemia negatively impacts neuronal survival in vivo: a study in [A30P]alpha-synuclein transgenic mouse (English)

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14 February 2020

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Yasemin Gürsoy-Ozdemir

2

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14 February 2020

4

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14 February 2020

author name string

Isin Unal-Cevik

1

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14 February 2020

Muge Yemisci

3

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14 February 2020

Gunfer Gurer

5

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14 February 2020

Alp Can

6

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14 February 2020

Veronica Müller

7

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14 February 2020

Philip J Kahle

8

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14 February 2020

Turgay Dalkara

9

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14 February 2020

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29 September 2010

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14 February 2020

Journal of Cerebral Blood Flow & Metabolism

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20877387%20AND%20SRC:MED&resulttype=core&format=json

14 February 2020

31

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14 February 2020

3

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14 February 2020

913-923

1 reference

Europe PubMed Central

PMC publication ID

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14 February 2020

Multiple proteins implicated in neurodegenerative diseases accumulate in axons after brain trauma in humans

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Cortical Lewy body disease and Parkinson's disease dementia.

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7 July 2018

Mechanisms of Parkinson's disease linked to pathological alpha-synuclein: new targets for drug discovery

1 reference

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7 July 2018

Opinion: What is the role of protein aggregation in neurodegeneration?

1 reference

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7 July 2018

Cellular abnormalities linked to endoplasmic reticulum dysfunction in cerebrovascular disease--therapeutic potential

1 reference

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7 July 2018

Ubiquitination of alpha-synuclein.

1 reference

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7 July 2018

Alpha-synuclein pathology does not predict extrapyramidal symptoms or dementia

1 reference

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7 July 2018

Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death

1 reference

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7 July 2018

Cerebral ischemia and the unfolded protein response

1 reference

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7 July 2018

Histochemical features of stress-induced aggregates in alpha-synuclein overexpressing cells.

1 reference

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7 July 2018

Unfolding the role of protein misfolding in neurodegenerative diseases

1 reference

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7 July 2018

Misfolded proteinase K-resistant hyperphosphorylated alpha-synuclein in aged transgenic mice with locomotor deterioration and in human alpha-synucleinopathies

1 reference

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7 July 2018

Biochemical characterization of the core structure of alpha-synuclein filaments

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063624

7 July 2018

[BSE and variant CJD: about the difficulties to establish a new pathogenetic principle].

1 reference

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7 July 2018

Selective insolubility of alpha-synuclein in human Lewy body diseases is recapitulated in a transgenic mouse model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063624

7 July 2018

Protein aggregation after focal brain ischemia and reperfusion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063624

7 July 2018

The significance of tau and alpha-synuclein inclusions in neurodegenerative diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063624

7 July 2018

Effect of the overexpression of wild-type or mutant alpha-synuclein on cell susceptibility to insult

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063624

7 July 2018

Aggresomes, inclusion bodies and protein aggregation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063624

7 July 2018

A hydrophobic stretch of 12 amino acid residues in the middle of alpha-synuclein is essential for filament assembly.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063624

7 July 2018

Subcellular localization of wild-type and Parkinson's disease-associated mutant alpha -synuclein in human and transgenic mouse brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063624

7 July 2018

Protein aggregation after transient cerebral ischemia.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063624

7 July 2018

Dopaminergic loss and inclusion body formation in alpha-synuclein mice: implications for neurodegenerative disorders

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063624

7 July 2018

Alpha-synuclein up-regulation in substantia nigra dopaminergic neurons following administration of the parkinsonian toxin MPTP.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063624

7 July 2018

Acceleration of oligomerization, not fibrillization, is a shared property of both alpha-synuclein mutations linked to early-onset Parkinson's disease: implications for pathogenesis and therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063624

7 July 2018

alpha-synuclein fibrillogenesis is nucleation-dependent. Implications for the pathogenesis of Parkinson's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063624

7 July 2018

Both familial Parkinson's disease mutations accelerate alpha-synuclein aggregation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063624

7 July 2018

Glial cytoplasmic inclusions in white matter oligodendrocytes of multiple system atrophy brains contain insoluble alpha-synuclein.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063624

7 July 2018

alpha-Synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with lewy bodies

1 reference

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7 July 2018

Aggregation of alpha-synuclein in Lewy bodies of sporadic Parkinson's disease and dementia with Lewy bodies.

1 reference

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7 July 2018

Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063624

7 July 2018

Alpha-synuclein in Lewy bodies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063624

7 July 2018

Molecular cloning of cDNA encoding an unrecognized component of amyloid in Alzheimer disease

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7 July 2018

Identification of two distinct synucleins from human brain

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7 July 2018

The rat brain synucleins; family of proteins transiently associated with neuronal membrane

1 reference

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7 July 2018

A new model of transient focal cerebral ischemia for inducing selective neuronal necrosis.

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21 January 2018

Accelerated in vitro fibril formation by a mutant alpha-synuclein linked to early-onset Parkinson disease

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21 January 2018

Age-dependent cognitive decline and amygdala pathology in alpha-synuclein transgenic mice

1 reference

https://api.crossref.org/works/10.1038%2FJCBFM.2010.170

21 January 2018

Role of endothelial nitric oxide generation and peroxynitrite formation in reperfusion injury after focal cerebral ischemia.

1 reference

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21 January 2018

Lysosomal rupture, necroapoptotic interactions and potential crosstalk between cysteine proteases in neurons shortly after focal ischemia

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21 January 2018

Presynaptic alpha-synuclein aggregates, not Lewy bodies, cause neurodegeneration in dementia with Lewy bodies.

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21 January 2018

Apoptosis detection in brain using low-magnification dark-field microscopy

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21 January 2018

Apoptotic and necrotic death mechanisms are concomitantly activated in the same cell after cerebral ischemia

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21 January 2018

Silent brain infarcts and the risk of dementia and cognitive decline

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21 January 2018

α-Synuclein Overexpression Protects against Paraquat-Induced Neurodegeneration

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26 October 2018

Epitope mapping of LB509, a monoclonal antibody directed against human alpha-synuclein

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

1 reference

https://pubmed.ncbi.nlm.nih.gov/20877387

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutant and wild type human alpha-synucleins assemble into elongated filaments with distinct morphologies in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/20877387

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

VEGF protects brain against focal ischemia without increasing blood--brain permeability when administered intracerebroventricularly

1 reference

https://pubmed.ncbi.nlm.nih.gov/20877387

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuropathology in mice expressing human alpha-synuclein

1 reference

https://pubmed.ncbi.nlm.nih.gov/20877387

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1038/JCBFM.2010.170

1 reference

Europe PubMed Central

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14 February 2020

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Europe PubMed Central

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14 February 2020

PubMed publication ID

1 reference

Europe PubMed Central

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14 February 2020

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