(Q34714815)

4 August 2017

title

The effects of aging vs. α7 nAChR subunit deficiency on the mouse brain transcriptome: aging beats the deficiency (English)

1 reference

4 August 2017

0 references

2

Avi Orr-Urtreger

1 reference

4 August 2017

Merav Kedmi

1

1 reference

4 August 2017

publication date

5 June 2010

1 reference

4 August 2017

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4 August 2017

volume

33

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4 August 2017

issue

1

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4 August 2017

page(s)

1-13

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Genes and gene expression modules associated with caloric restriction and aging in the laboratory mouse

4 August 2017

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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Gene expression changes in the course of normal brain aging are sexually dimorphic

7 July 2018

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7 July 2018

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Large recurrent microdeletions associated with schizophrenia

7 July 2018

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Rare chromosomal deletions and duplications increase risk of schizophrenia

7 July 2018

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Update in the epidemiology of Parkinson's disease

7 July 2018

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Analyzing real-time PCR data by the comparative C(T) method

7 July 2018

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Preclinical characterization of A-582941: a novel alpha7 neuronal nicotinic receptor agonist with broad spectrum cognition-enhancing properties

7 July 2018

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Yeast life span extension by depletion of 60s ribosomal subunits is mediated by Gcn4.

7 July 2018

1 reference

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Ageing and the regulation of protein synthesis: a balancing act?

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063643

A recurrent 15q13.3 microdeletion syndrome associated with mental retardation and seizures

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063643

Genome-wide analysis of aging and learning-related genes in the hippocampal dentate gyrus

7 July 2018

1 reference

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Decreased withdrawal symptoms but normal tolerance to nicotine in mice null for the alpha7 nicotinic acetylcholine receptor subunit

7 July 2018

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An allosteric modulator of the alpha7 nicotinic acetylcholine receptor possessing cognition-enhancing properties in vivo

7 July 2018

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The importance of being subtle: small changes in calcium homeostasis control cognitive decline in normal aging

7 July 2018

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PICK1 interacts with alpha7 neuronal nicotinic acetylcholine receptors and controls their clustering.

7 July 2018

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Postnatal upregulation of alpha4 and alpha3 nicotinic receptor subunits in the brain of alpha7 nicotinic receptor-deficient mice

7 July 2018

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Lifespan extension by conditions that inhibit translation in Caenorhabditis elegans

7 July 2018

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Effects of melatonin and age on gene expression in mouse CNS using microarray analysis

7 July 2018

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Differential brain transcriptome of beta4 nAChR subunit-deficient mice: is it the effect of the null mutation or the background strain?

7 July 2018

1 reference

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Transcriptional profiling of aging in human muscle reveals a common aging signature

7 July 2018

1 reference

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Neural plasticity in the ageing brain

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063643

Long-lasting cognitive improvement with nicotinic receptor agonists: mechanisms of pharmacokinetic-pharmacodynamic discordance

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063643

A transcriptional profile of aging in the human kidney

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063643

Gene regulation and DNA damage in the ageing human brain

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063643

DAVID: Database for Annotation, Visualization, and Integrated Discovery

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063643

Nicotinic receptors in aging and dementia

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063643

Nicotinic alpha 7 receptors: synaptic options and downstream signaling in neurons

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063643

Modification of brain aging and neurodegenerative disorders by genes, diet, and behavior

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063643

DNA microarray analysis of the aging brain

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063643

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063643

Minimum information about a microarray experiment (MIAME)-toward standards for microarray data

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063643

Linkage disequilibrium for schizophrenia at the chromosome 15q13-14 locus of the alpha7-nicotinic acetylcholine receptor subunit gene (CHRNA7)

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063643

The effects of aging on gene expression in the hypothalamus and cortex of mice

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063643

Smoking and Parkinson's and Alzheimer's disease: review of the epidemiological studies

7 July 2018

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063643

7 July 2018

https://api.crossref.org/works/10.1007%2FS11357-010-9155-7

Cytoskeletal links of neuronal acetylcholine receptors containing alpha 7 subunits.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063643

Alpha7 nicotinic receptor subunits are not necessary for hippocampal-dependent learning or sensorimotor gating: a behavioral characterization of Acra7-deficient mice.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063643

Increased neurodegeneration during ageing in mice lacking high-affinity nicotine receptors

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063643

Mice deficient in the alpha7 neuronal nicotinic acetylcholine receptor lack alpha-bungarotoxin binding sites and hippocampal fast nicotinic currents

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063643

A missense mutation in the neuronal nicotinic acetylcholine receptor alpha 4 subunit is associated with autosomal dominant nocturnal frontal lobe epilepsy

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063643

Comparison of gene expression in old versus young rat hippocampus by cDNA array

7 July 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11357-010-9155-7

Ribosome dysfunction is an early event in Alzheimer's disease.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11357-010-9155-7

Molecular aging in human prefrontal cortex is selective and continuous throughout adult life.

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11357-010-9155-7

Inflammatory repertoire of Alzheimer's disease and nondemented elderly microglia in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11357-010-9155-7

Hippocampal expression analyses reveal selective association of immediate-early, neuroenergetic, and myelinogenic pathways with cognitive impairment in aged rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11357-010-9155-7

Pathologic and nicotinic receptor binding differences between mild cognitive impairment, Alzheimer disease, and normal aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11357-010-9155-7

Lower core body temperature and attenuated nicotine-induced hypothermic response in mice lacking the beta4 neuronal nicotinic acetylcholine receptor subunit

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11357-010-9155-7

Immune response gene expression increases in the aging murine hippocampus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11357-010-9155-7

Nicotine improves sustained attention in mice: evidence for involvement of the alpha7 nicotinic acetylcholine receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11357-010-9155-7

Gene Microarrays in Hippocampal Aging: Statistical Profiling Identifies Novel Processes Correlated with Cognitive Impairment

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063643

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063643

Preclinical Characterization of A-582941: A Novel α7 Neuronal Nicotinic Receptor Agonist with Broad Spectrum Cognition-Enhancing Properties

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3063643

Chronic lung inflammation in aging mice

9 December 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20526689

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Gene-expression profile of the ageing brain in mice

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20526689

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Impaired attention is central to the cognitive deficits observed in alpha 7 deficient mice

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20526689

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1007/S11357-010-9155-7

1 reference

4 August 2017

1 reference

4 August 2017

1 reference