(Q34721752)

English

MEK/ERK inhibitor U0126 increases the radiosensitivity of rhabdomyosarcoma cells in vitro and in vivo by downregulating growth and DNA repair signals

scientific article published in January 2011

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scholarly article

1 reference

Europe PubMed Central

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19 January 2020

MEK/ERK inhibitor U0126 increases the radiosensitivity of rhabdomyosarcoma cells in vitro and in vivo by downregulating growth and DNA repair signals (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21220498%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

rhabdomyosarcoma

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based on heuristic

inferred from title

Francesco Marampon

1

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19 January 2020

Giovanni Luca Gravina

2

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19 January 2020

Carmela Ciccarelli Priori

8

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19 January 2020

13

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19 January 2020

Richard Pestell

11

object named as

Richard G Pestell

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19 January 2020

author name string

Agnese Di Rocco

3

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19 January 2020

Pierluigi Bonfili

4

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19 January 2020

Mario Di Staso

5

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19 January 2020

Caterina Fardella

6

1 reference

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19 January 2020

Lorella Polidoro

7

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19 January 2020

Claudio Festuccia

9

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19 January 2020

Vladimir M Popov

10

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19 January 2020

Vincenzo Tombolini

12

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19 January 2020

publication date

1 January 2011

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19 January 2020

Molecular Cancer Therapeutics

1 reference

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19 January 2020

10

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19 January 2020

1

1 reference

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19 January 2020

159-168

1 reference

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19 January 2020

Targeting DNA-PKcs and ATM with miR-101 sensitizes tumors to radiation

1 reference

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7 July 2018

The mitogen-activated protein/extracellular signal-regulated kinase kinase 1/2 inhibitor AZD6244 (ARRY-142886) enhances the radiation responsiveness of lung and colorectal tumor xenografts

1 reference

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7 July 2018

RAS signaling dysregulation in human embryonal Rhabdomyosarcoma

1 reference

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7 July 2018

MEK/ERK inhibitor U0126 affects in vitro and in vivo growth of embryonal rhabdomyosarcoma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064485

7 July 2018

Cyclin D1 in low-dose radiation-induced adaptive resistance.

1 reference

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7 July 2018

DNA-dependent protein kinase catalytic subunit modulates the stability of c-Myc oncoprotein.

1 reference

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7 July 2018

Nerve Growth factor regulation of cyclin D1 in PC12 cells through a p21RAS extracellular signal-regulated kinase pathway requires cooperative interactions between Sp1 and nuclear factor-kappaB

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7 July 2018

The relationship between the down-regulation of DNA-PKcs or Ku70 and the chemosensitization in human cervical carcinoma cell line HeLa.

1 reference

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7 July 2018

ROCK2 and its alternatively spliced isoform ROCK2m positively control the maturation of the myogenic program

1 reference

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7 July 2018

BRAF V600E maintains proliferation, transformation, and tumorigenicity of BRAF-mutant papillary thyroid cancer cells

1 reference

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7 July 2018

Tumor cell radiosensitivity is a major determinant of tumor response to radiation

1 reference

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7 July 2018

Down-regulation of c-Myc following MEK/ERK inhibition halts the expression of malignant phenotype in rhabdomyosarcoma and in non muscle-derived human tumors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064485

7 July 2018

New paradigms in anticancer therapy: targeting multiple signaling pathways with kinase inhibitors.

1 reference

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7 July 2018

Blockage of epidermal growth factor receptor-phosphatidylinositol 3-kinase-AKT signaling increases radiosensitivity of K-RAS mutated human tumor cells in vitro by affecting DNA repair.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064485

7 July 2018

MAPK signal specificity: the right place at the right time

1 reference

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7 July 2018

Transcriptional regulation and transformation by Myc proteins

1 reference

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7 July 2018

Getting at MYC through RAS.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064485

7 July 2018

Downregulation of c-myc protein by siRNA-mediated silencing of DNA-PKcs in HeLa cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064485

7 July 2018

A signalling pathway controlling c-Myc degradation that impacts oncogenic transformation of human cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064485

7 July 2018

Protein measurement with the Folin phenol reagent

1 reference

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7 July 2018

Conferring specificity on the ubiquitous Raf/MEK signalling pathway

1 reference

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7 July 2018

Pharmacological inhibitors of the ERK signaling pathway: application as anticancer drugs

1 reference

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7 July 2018

Rhabdomyosarcoma in adults. A retrospective analysis of 171 patients treated at a single institution

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064485

7 July 2018

Enhanced antitumor activity of anti-epidermal growth factor receptor monoclonal antibody IMC-C225 in combination with irinotecan (CPT-11) against human colorectal tumor xenografts

1 reference

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7 July 2018

Ras inhibitors and radiation therapy

1 reference

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7 July 2018

Chromosomal stability and the DNA double-stranded break connection

1 reference

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Adjuvant chemotherapy for adult soft tissue sarcomas of the extremities and girdles: results of the Italian randomized cooperative trial

1 reference

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7 July 2018

Multiple Ras-dependent phosphorylation pathways regulate Myc protein stability.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064485

7 July 2018

Activation of the cyclin D1 gene by the E1A-associated protein p300 through AP-1 inhibits cellular apoptosis

1 reference

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7 July 2018

Role of radiation therapy in parameningeal rhabdomyosarcoma

1 reference

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7 July 2018

Oncogene Expression and Cellular Radiation Resistance: A Modulatory Role for c-myc.

1 reference

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7 July 2018

Cyclin D1 overexpression enhances radiation-induced apoptosis and radiosensitivity in a breast tumor cell line

1 reference

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7 July 2018

Identification of a novel inhibitor of mitogen-activated protein kinase kinase

1 reference

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7 July 2018

Absence of p350 subunit of DNA-activated protein kinase from a radiosensitive human cell line

1 reference

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Radiation-induced DNA damage and repair in cells of a radiosensitive human malignant glioma cell line

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7 July 2018

The ras oncogenes

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7 July 2018

Synergistic effect of the v-myc oncogene with H-ras on radioresistance.

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7 July 2018

The role of the H-ras oncogene in radiation resistance and metastasis

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26 October 2018

Relationship between cyclin D1 expression and poor radioresponse of murine carcinomas

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Distinct Initiation and Maintenance Mechanisms Cooperate to Induce G1 Cell Cycle Arrest in Response to DNA Damage

1 reference

https://pubmed.ncbi.nlm.nih.gov/21220498

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sustained loss of a neoplastic phenotype by brief inactivation of MYC

1 reference

https://pubmed.ncbi.nlm.nih.gov/21220498

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1158/1535-7163.MCT-10-0631

1 reference

Europe PubMed Central

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19 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21220498%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21220498%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

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