(Q34726610)

4 August 2017

title

Mechanisms of amine accumulation in, and egress from, lysosomes (English)

1 reference

4 August 2017

Stephen D B Goldman

1

1 reference

4 August 2017

Ryan S Funk

series ordinal

2

1 reference

4 August 2017

Roger A Rajewski

series ordinal

3

1 reference

4 August 2017

Jeffrey P Krise

series ordinal

4

1 reference

4 August 2017

publication date

1 November 2009

1 reference

4 August 2017

1 reference

4 August 2017

volume

1

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4 August 2017

issue

8

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4 August 2017

page(s)

1445-1459

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describes a project that uses

4 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3065188/fullTextXML

inferred from PubMed Central ID database lookup

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7 July 2018

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Lysosomal sequestration of amine-containing drugs: analysis and therapeutic implications

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7 July 2018

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7 July 2018

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7 July 2018

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A novel assay reveals that weakly basic model compounds concentrate in lysosomes to an extent greater than pH-partitioning theory would predict

7 July 2018

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Niemann-Pick C1 protein facilitates the efflux of the anticancer drug daunorubicin from cells according to a novel vesicle-mediated pathway

7 July 2018

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Selective determination of the doxorubicin content of individual acidic organelles in impure subcellular fractions

7 July 2018

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Massive cell vacuolization induced by organic amines such as procainamide.

7 July 2018

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7 July 2018

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7 July 2018

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3-Aminopropanal, formed during cerebral ischaemia, is a potent lysosomotropic neurotoxin

7 July 2018

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Lysosomal destabilization during macrophage damage induced by cholesterol oxidation products

7 July 2018

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Transmembrane molecular pump activity of Niemann-Pick C1 protein

7 July 2018

1 reference

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Lysosome-endosome fusion and lysosome biogenesis.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3065188

Lysosomal trapping as an important mechanism involved in the cellular distribution of perazine and in pharmacokinetic interaction with antidepressants

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3065188

The role of lysosomes in the cellular distribution of thioridazine and potential drug interactions

7 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3065188

The fate of ferriprotorphyrin IX in malaria infected erythrocytes in conjunction with the mode of action of antimalarial drugs

7 July 2018

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The Niemann-Pick C1 protein resides in a vesicular compartment linked to retrograde transport of multiple lysosomal cargo

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3065188

Cerebral ischemia enhances polyamine oxidation: identification of enzymatically formed 3-aminopropanal as an endogenous mediator of neuronal and glial cell death

7 July 2018

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Functional intracellular P-glycoprotein

7 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3065188

Interactions between promazine and antidepressants at the level of cellular distribution

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3065188

Lysosome membrane permeability to amines.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3065188

Photo-oxidative disruption of lysosomal membranes causes apoptosis of cultured human fibroblasts

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3065188

Contribution of lysosomal trapping to the total tissue uptake of psychotropic drugs

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3065188

Intracellular localization, vesicular accumulation and kinetics of daunorubicin in sensitive and multidrug-resistant gastric carcinoma EPG85-257 cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3065188

Cytoplasmic vacuolation of mouse peritoneal macrophages and the uptake into lysosomes of weakly basic substances

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3065188

7 July 2018

Functions of lysosomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3065188

Commentary. Lysosomotropic agents

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3065188

Lysosomes, pH and the Anti-malarial Action of Chloroquine

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3065188

The effects of osmotic pressure on procaine-induced vacuolation in cell culture.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3065188

Digestive activity of lysosomes. 3. The digestion of lipids by extracts of rat liver lysosomes.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3065188

Selective lysosomal uptake and accumulation of the beta-adrenergic antagonist propranolol in cultured and isolated cell systems

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3065188

Correlation between growth inhibition and intranuclear doxorubicin and 4'-deoxy-4'-iododoxorubicin quantitated in living K562 cells by microspectrofluorometry.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3065188

Role of the aclacinomycin A--doxorubicin association in reversal of doxorubicin resistance in K562 tumour cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3065188

A multicompartmental model of fluid-phase endocytosis in rabbit liver parenchymal cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3065188

Passive diffusion of non-electrolytes across the lysosome membrane

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3065188

The intracellular transport of low density lipoprotein-derived cholesterol is defective in Niemann-Pick type C fibroblasts

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3065188

Nephrotoxicity of aminoglycoside antibiotics.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3065188

Drug-phospholipid interactions: role in aminoglycoside nephrotoxicity

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3065188

A novel mechanism for regulation of vacuolar acidification

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3065188

MECHANISM OF DRUG-INDUCED VACUOLIZATION IN TISSUE CULTURE.

7 July 2018

1 reference

https://api.crossref.org/works/10.4155%2FBIO.09.128

Procaine-induced enhancement of fluid-phase endocytosis and inhibition of exocytosis in human skin fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FBIO.09.128

Flux of fatty acids through NPC1 lysosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FBIO.09.128

Quantitation of the lysosomotropic character of cationic amphiphilic drugs using the fluorescent basic amine Red DND-99.

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FBIO.09.128

Influence of lipophilicity and lysosomal accumulation on tissue distribution kinetics of basic drugs: a physiologically based pharmacokinetic model

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3065188

Digestive activity of lysosomes. II. The digestion of macromolecular carbohydrates by extracts of rat liver lysosomes.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3065188

Digestive activity of lysosomes. I. The digestion of proteins by extracts of rat liver lysosomes

26 October 2018

1 reference

12 December 2020

Uptake of imipramine in rat liver lysosomes in vitro and its inhibition by basic drugs

1 reference

12 December 2020

Lysosome proton pump identified

1 reference

12 December 2020

Structural and physical changes in lysosomes from isolated rat hepatocytes treated with methylamine

1 reference

12 December 2020

Group C Niemann-Pick disease: faulty regulation of low-density lipoprotein uptake and cholesterol storage in cultured fibroblasts

1 reference

12 December 2020

Organic cation transport by rat liver lysosomes

1 reference

12 December 2020

Dense core lysosomes can fuse with late endosomes and are re-formed from the resultant hybrid organelles

1 reference

12 December 2020

Application of magnetic chromatography to the isolation of lysosomes from fibroblasts of patients with lysosomal storage disorders

1 reference

12 December 2020

Identifiers

DOI

10.4155/BIO.09.128

1 reference

4 August 2017

1 reference

4 August 2017

1 reference