(Q34728302)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23686572%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

title

p14ARF induces apoptosis via an entirely caspase-3-dependent mitochondrial amplification loop (English)

1 reference

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1 March 2020

4

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1 March 2020

Cindrilla Chumduri

5

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1 March 2020

author name string

Ana Milojkovic

1

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1 March 2020

Philipp G Hemmati

2

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1 March 2020

Annika Müer

3

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1 March 2020

Reiner U Jänicke

6

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1 March 2020

Bernd Gillissen

7

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1 March 2020

Peter T Daniel

8

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1 March 2020

language of work or name

English

0 references

publication date

1 August 2013

1 reference

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International Journal of Cancer

1 March 2020

published in

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1 March 2020

volume

133

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1 March 2020

issue

11

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1 March 2020

page(s)

2551-2562

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Cancer-associated mutations at the INK4a locus cancel cell cycle arrest by p16INK4a but not by the alternative reading frame protein p19ARF.

1 March 2020

cites work

1 reference

E1A signaling to p53 involves the p19(ARF) tumor suppressor

21 January 2018

1 reference

p19(Arf) induces p53-dependent apoptosis during abelson virus-mediated pre-B cell transformation

21 January 2018

1 reference

Myc signaling via the ARF tumor suppressor regulates p53-dependent apoptosis and immortalization

21 January 2018

1 reference

Principles of tumor suppression

21 January 2018

1 reference

ARF function does not require p53 stabilization or Mdm2 relocalization

21 January 2018

1 reference

p14ARF induces G2 arrest and apoptosis independently of p53 leading to regression of tumours established in nude mice

21 January 2018

1 reference

p19ARF directly and differentially controls the functions of c-Myc independently of p53.

21 January 2018

1 reference

Adenovirus-mediated overexpression of p14(ARF) induces p53 and Bax-independent apoptosis

21 January 2018

1 reference

Cooperative effect of p21Cip1/WAF-1 and 14-3-3sigma on cell cycle arrest and apoptosis induction by p14ARF.

21 January 2018

1 reference

Loss of p21 disrupts p14 ARF-induced G1 cell cycle arrest but augments p14 ARF-induced apoptosis in human carcinoma cells

21 January 2018

1 reference

p14ARF triggers G2 arrest through ERK-mediated Cdc25C phosphorylation, ubiquitination and proteasomal degradation.

21 January 2018

1 reference

Divorcing ARF and p53: an unsettled case

21 January 2018

1 reference

p14ARF induces G2 cell cycle arrest in p53- and p21-deficient cells by down-regulating p34cdc2 kinase activity

21 January 2018

1 reference

Dynamic expression profile of p21WAF1/CIP1 and Ki-67 predicts survival in rectal carcinoma treated with preoperative radiochemotherapy

21 January 2018

1 reference

Induction of cell death by the BH3-only Bcl-2 homolog Nbk/Bik is mediated by an entirely Bax-dependent mitochondrial pathway

21 January 2018

1 reference

Multidomain Bcl-2 homolog Bax but not Bak mediates synergistic induction of apoptosis by TRAIL and 5-FU through the mitochondrial apoptosis pathway

21 January 2018

1 reference

p14ARF activates a Tip60-dependent and p53-independent ATM/ATR/CHK pathway in response to genotoxic stress

21 January 2018

1 reference

Caspase-3 is required for DNA fragmentation and morphological changes associated with apoptosis

21 January 2018

1 reference

Overexpression of caspase-3 restores sensitivity for drug-induced apoptosis in breast cancer cell lines with acquired drug resistance

21 January 2018

1 reference

Effects of adenovirus-mediated p16INK4A expression on cell cycle arrest are determined by endogenous p16 and Rb status in human cancer cells

21 January 2018

1 reference

Systematic genetic dissection of p14ARF-mediated mitochondrial cell death signaling reveals a key role for p21CDKN1 and the BH3-only protein Puma/bbc3.

21 January 2018

1 reference

Induction of p21CIP/WAF-1 and G2 arrest by ionizing irradiation impedes caspase-3-mediated apoptosis in human carcinoma cells

21 January 2018

1 reference

Caspase-3 is required for alpha-fodrin cleavage but dispensable for cleavage of other death substrates in apoptosis

21 January 2018

1 reference

Activation of the mitochondrial death pathway is commonly mediated by a preferential engagement of Bak.

21 January 2018

1 reference

Human ARF binds E2F1 and inhibits its transcriptional activity.

21 January 2018

1 reference

p19ARF targets certain E2F species for degradation.

21 January 2018

1 reference

p14(ARF) regulates E2F activity

21 January 2018

1 reference

E2F transcriptional repressor complexes are critical downstream targets of p19(ARF)/p53-induced proliferative arrest

21 January 2018

1 reference

Disruption of p53 in human cancer cells alters the responses to therapeutic agents

21 January 2018

1 reference

PUMA mediates the apoptotic response to p53 in colorectal cancer cells

21 January 2018

1 reference

Bak functionally complements for loss of Bax during p14ARF-induced mitochondrial apoptosis in human cancer cells

21 January 2018

1 reference

p14(ARF)-induced apoptosis in p53 protein-deficient cells is mediated by BH3-only protein-independent derepression of Bak protein through down-regulation of Mcl-1 and Bcl-xL proteins.

21 January 2018

1 reference

Caspase-2 permeabilizes the outer mitochondrial membrane and disrupts the binding of cytochrome c to anionic phospholipids

21 January 2018

1 reference

The unpredictable caspase-2: what can it do?

21 January 2018

1 reference

DISC-mediated activation of caspase-2 in DNA damage-induced apoptosis

21 January 2018

1 reference

Bid-induced conformational change of Bax is responsible for mitochondrial cytochrome c release during apoptosis

21 January 2018

1 reference

Nonredundant role of Bax and Bak in Bid-mediated apoptosis

21 January 2018

1 reference

Apoptosis initiated when BH3 ligands engage multiple Bcl-2 homologs, not Bax or Bak

21 January 2018

1 reference

p53- and Mdm2-Independent Repression of NF-κB Transactivation by the ARF Tumor Suppressor

21 January 2018

1 reference

Uncoupling of S phase and mitosis induced by anticancer agents in cells lacking p21

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1002/IJC.28279

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23686572%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

1 reference