(Q33186542)

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p14ARF induces G2 arrest and apoptosis independently of p53 leading to regression of tumours established in nude mice

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Europe PubMed Central

23 July 2017

p14ARF induces G2 arrest and apoptosis independently of p53 leading to regression of tumours established in nude mice (English)

1 reference

Europe PubMed Central

23 July 2017

apoptotic process

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Elisabeth Brambilla

4

object named as

Elisabeth Brambilla

1 reference

Europe PubMed Central

23 July 2017

author name string

Béatrice Eymin

1

1 reference

Europe PubMed Central

23 July 2017

Camille Leduc

2

1 reference

Europe PubMed Central

23 July 2017

Jean-Luc Coll

3

1 reference

Europe PubMed Central

23 July 2017

Sylvie Gazzeri

5

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Europe PubMed Central

23 July 2017

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publication date

1 March 2003

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Europe PubMed Central

23 July 2017

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Europe PubMed Central

23 July 2017

22

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Europe PubMed Central

23 July 2017

12

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Europe PubMed Central

23 July 2017

1822-1835

1 reference

Europe PubMed Central

23 July 2017

https://scigraph.springernature.com/pub.10.1038/sj.onc.1206303

0 references

p53 controls both the G2/M and the G1 cell cycle checkpoints and mediates reversible growth arrest in human fibroblasts

1 reference

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21 January 2018

Mechanism of ultraviolet B-induced cell cycle arrest in G2/M phase in immortalized skin keratinocytes with defective p53.

1 reference

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21 January 2018

Cdc2 regulatory factors

1 reference

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21 January 2018

The Chk1 protein kinase and the Cdc25C regulatory pathways are targets of the anticancer agent UCN-01

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21 January 2018

TUNEL apoptotic cell detection in tissue sections: critical evaluation and improvement

1 reference

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21 January 2018

p55CDC25 is a nuclear protein required for the initiation of mitosis in human cells.

1 reference

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21 January 2018

p19(Arf) induces p53-dependent apoptosis during abelson virus-mediated pre-B cell transformation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206303

21 January 2018

Structural basis of cyclin-dependent kinase activation by phosphorylation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206303

21 January 2018

Control of mitosis by changes in the subcellular location of cyclin-B1-Cdk1 and Cdc25C

1 reference

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21 January 2018

P19(ARF) stabilizes p53 by blocking nucleo-cytoplasmic shuttling of Mdm2

1 reference

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21 January 2018

p21 Inhibits Thr161Phosphorylation of Cdc2 to Enforce the G2DNA Damage Checkpoint

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206303

21 January 2018

p14ARF links the tumour suppressors RB and p53.

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

The role of inhibitory phosphorylation of CDC2 following DNA replication block and radiation-induced damage in human cells

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Requirement for p53 and p21 to sustain G2 arrest after DNA damage

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206303

7 January 2021

based on heuristic

inferred from DOI database lookup

p16INK4A and p19ARF act in overlapping pathways in cellular immortalization

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206303

7 January 2021

based on heuristic

inferred from DOI database lookup

The INK4a/ARF tumor suppressor: one gene--two products--two pathways

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206303

7 January 2021

based on heuristic

inferred from DOI database lookup

Inhibition of v-Abl transformation by p53 and p19ARF

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206303

7 January 2021

based on heuristic

inferred from DOI database lookup

E1A signaling to p53 involves the p19(ARF) tumor suppressor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206303

7 January 2021

based on heuristic

inferred from DOI database lookup

Regulation of a senescence checkpoint response by the E2F1 transcription factor and p14(ARF) tumor suppressor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206303

7 January 2021

based on heuristic

inferred from DOI database lookup

Cell cycle: will the real Cdk-activating kinase please stand up

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206303

7 January 2021

based on heuristic

inferred from DOI database lookup

Nuclear accumulation of p21Cip1 at the onset of mitosis: a role at the G2/M-phase transition

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206303

7 January 2021

based on heuristic

inferred from DOI database lookup

Cell cycle checkpoints: preventing an identity crisis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206303

7 January 2021

based on heuristic

inferred from DOI database lookup

Human ARF binds E2F1 and inhibits its transcriptional activity.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206303

7 January 2021

based on heuristic

inferred from DOI database lookup

Cdc25 Mitotic Inducer Targeted by Chk1 DNA Damage Checkpoint Kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206303

7 January 2021

based on heuristic

inferred from DOI database lookup

Cdc25-dependent activation of cyclin A/cdk2 is blocked in G2 phase arrested cells independently of ATM/ATR.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206303

7 January 2021

based on heuristic

inferred from DOI database lookup

Inhibition of cyclin-dependent kinases by p21

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206303

7 January 2021

based on heuristic

inferred from DOI database lookup

Checkpoints: controls that ensure the order of cell cycle events

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206303

7 January 2021

based on heuristic

inferred from DOI database lookup

Adenovirus-mediated overexpression of p14(ARF) induces p53 and Bax-independent apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206303

7 January 2021

based on heuristic

inferred from DOI database lookup

Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product p19ARF

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206303

7 January 2021

based on heuristic

inferred from DOI database lookup

The cdc25 protein controls tyrosine dephosphorylation of the cdc2 protein in a cell-free system

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206303

7 January 2021

based on heuristic

inferred from DOI database lookup

Immunolocalization of human p14(ARF) to the granular component of the interphase nucleolus

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206303

7 January 2021

based on heuristic

inferred from DOI database lookup

p53 is required for radiation-induced apoptosis in mouse thymocytes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206303

7 January 2021

based on heuristic

inferred from DOI database lookup

Rapid destruction of human Cdc25A in response to DNA damage

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206303

7 January 2021

based on heuristic

inferred from DOI database lookup

Effects of p21(Cip1/Waf1) at both the G1/S and the G2/M cell cycle transitions: pRb is a critical determinant in blocking DNA replication and in preventing endoreduplication

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206303

7 January 2021

based on heuristic

inferred from DOI database lookup

The G2-phase DNA-damage checkpoint

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206303

7 January 2021

based on heuristic

inferred from DOI database lookup

p19ARF links the tumour suppressor p53 to Ras

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206303

7 January 2021

based on heuristic

inferred from DOI database lookup

Mitotic and G2 checkpoint control: regulation of 14-3-3 protein binding by phosphorylation of Cdc25C on serine-216

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206303

7 January 2021

based on heuristic

inferred from DOI database lookup

Alternative reading frames of the INK4a tumor suppressor gene encode two unrelated proteins capable of inducing cell cycle arrest

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206303

7 January 2021

based on heuristic

inferred from DOI database lookup

Virus-mediated killing of cells that lack p53 activity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206303

7 January 2021

based on heuristic

inferred from DOI database lookup

Cdc2 tyrosine phosphorylation is required for the DNA damage checkpoint in fission yeast

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Conservation of the Chk1 checkpoint pathway in mammals: linkage of DNA damage to Cdk regulation through Cdc25

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206303

7 January 2021

based on heuristic

inferred from DOI database lookup

Inactivation of the INK4A/ARF locus frequently coexists with TP53 mutations in non-small cell lung cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206303

7 January 2021

based on heuristic

inferred from DOI database lookup

A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206303

7 January 2021

based on heuristic

inferred from DOI database lookup

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206303

7 January 2021

based on heuristic

inferred from DOI database lookup

Tumor surveillance via the ARF-p53 pathway.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206303

7 January 2021

based on heuristic

inferred from DOI database lookup

The INK4a/ARF network in tumour suppression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206303

7 January 2021

based on heuristic

inferred from DOI database lookup

The alternative product from the human CDKN2A locus, p14(ARF), participates in a regulatory feedback loop with p53 and MDM2.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206303

7 January 2021

based on heuristic

inferred from DOI database lookup

Dephosphorylation and activation of a p34cdc2/cyclin B complex in vitro by human CDC25 protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206303

7 January 2021

based on heuristic

inferred from DOI database lookup

Cell-cycle checkpoint kinases: checking in on the cell cycle

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206303

7 January 2021

based on heuristic

inferred from DOI database lookup

Involvement of the MKK6-p38gamma cascade in gamma-radiation-induced cell cycle arrest

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206303

7 January 2021

based on heuristic

inferred from DOI database lookup

Human p14(ARF)-mediated cell cycle arrest strictly depends on intact p53 signaling pathways

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206303

7 January 2021

based on heuristic

inferred from DOI database lookup

p53-independent functions of the p19(ARF) tumor suppressor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206303

7 January 2021

based on heuristic

inferred from DOI database lookup

Nucleolar Arf sequesters Mdm2 and activates p53

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206303

7 January 2021

based on heuristic

inferred from DOI database lookup

A DNA damage checkpoint meets the cell cycle engine

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206303

7 January 2021

based on heuristic

inferred from DOI database lookup

p53 regulates Cdc2 independently of inhibitory phosphorylation to reinforce radiation-induced G2 arrest in human cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206303

7 January 2021

based on heuristic

inferred from DOI database lookup

Two S-phase checkpoint systems, one involving the function of both BIME and Tyr15 phosphorylation of p34cdc2, inhibit NIMA and prevent premature mitosis.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206303

7 January 2021

based on heuristic

inferred from DOI database lookup

Overexpression of ErbB2 blocks Taxol-induced apoptosis by upregulation of p21Cip1, which inhibits p34Cdc2 kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206303

7 January 2021

based on heuristic

inferred from DOI database lookup

Mutations in human ARF exon 2 disrupt its nucleolar localization and impair its ability to block nuclear export of MDM2 and p53

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206303

7 January 2021

based on heuristic

inferred from DOI database lookup

Myc signaling via the ARF tumor suppressor regulates p53-dependent apoptosis and immortalization

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206303

7 January 2021

based on heuristic

inferred from DOI database lookup

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10.1038/SJ.ONC.1206303

1 reference

Europe PubMed Central

23 July 2017

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1 reference

Europe PubMed Central

23 July 2017

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