(Q34732874)

English

Treatment with CNX-011-67, a novel GPR40 agonist, delays onset and progression of diabetes and improves beta cell preservation and function in male ZDF rats

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scholarly article

1 reference

Europe PubMed Central

4 August 2017

Treatment with CNX-011-67, a novel GPR40 agonist, delays onset and progression of diabetes and improves beta cell preservation and function in male ZDF rats (English)

1 reference

Europe PubMed Central

4 August 2017

author name string

Nagesh Gowda

1

1 reference

Europe PubMed Central

4 August 2017

Anilkumar Dandu

2

1 reference

Europe PubMed Central

4 August 2017

Jaideep Singh

3

1 reference

Europe PubMed Central

4 August 2017

Sanghamitra Biswas

4

1 reference

Europe PubMed Central

4 August 2017

Vijaya Raghav

5

1 reference

Europe PubMed Central

4 August 2017

Mudigere N Lakshmi

6

1 reference

Europe PubMed Central

4 August 2017

Pavagada C Shilpa

7

1 reference

Europe PubMed Central

4 August 2017

Venkategowda Sunil

8

1 reference

Europe PubMed Central

4 August 2017

Ashokkumar Reddy

9

1 reference

Europe PubMed Central

4 August 2017

Manojkumar Sadasivuni

10

1 reference

Europe PubMed Central

4 August 2017

Kumaraswamy Aparna

11

1 reference

Europe PubMed Central

4 August 2017

Mahesh Kumar Verma

12

1 reference

Europe PubMed Central

4 August 2017

Yoganand Moolemath

13

1 reference

Europe PubMed Central

4 August 2017

Mammen O Anup

14

1 reference

Europe PubMed Central

4 August 2017

Marikunte V Venkataranganna

15

1 reference

Europe PubMed Central

4 August 2017

Baggavalli P Somesh

16

1 reference

Europe PubMed Central

4 August 2017

Madanahalli R Jagannath

17

1 reference

Europe PubMed Central

4 August 2017

publication date

21 May 2013

1 reference

Europe PubMed Central

4 August 2017

BMC pharmacology & toxicology

1 reference

Europe PubMed Central

4 August 2017

14

1 reference

Europe PubMed Central

4 August 2017

28

1 reference

Europe PubMed Central

4 August 2017

https://scigraph.springernature.com/pub.10.1186/2050-6511-14-28

0 references

Randomized, double-blind, dose-ranging study of TAK-875, a novel GPR40 agonist, in Japanese patients with inadequately controlled type 2 diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3668190

7 July 2018

A potent class of GPR40 full agonists engages the enteroinsular axis to promote glucose control in rodents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3668190

7 July 2018

Thioredoxin-interacting protein mediates ER stress-induced β cell death through initiation of the inflammasome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3668190

7 July 2018

GLP-1 based therapies: differential effects on fasting and postprandial glucose

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3668190

7 July 2018

AMG 837: a novel GPR40/FFA1 agonist that enhances insulin secretion and lowers glucose levels in rodents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3668190

7 July 2018

TAK-875, an orally available G protein-coupled receptor 40/free fatty acid receptor 1 agonist, enhances glucose-dependent insulin secretion and improves both postprandial and fasting hyperglycemia in type 2 diabetic rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3668190

7 July 2018

A practical guide to rodent islet isolation and assessment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3668190

7 July 2018

Peroxisome proliferator-activated receptor alpha (PPARalpha) protects against oleate-induced INS-1E beta cell dysfunction by preserving carbohydrate metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3668190

7 July 2018

Lack of TXNIP protects against mitochondria-mediated apoptosis but not against fatty acid-induced ER stress-mediated beta-cell death

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3668190

7 July 2018

Selective small-molecule agonists of G protein-coupled receptor 40 promote glucose-dependent insulin secretion and reduce blood glucose in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3668190

7 July 2018

Thioredoxin-interacting protein: a critical link between glucose toxicity and beta-cell apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3668190

7 July 2018

Pioglitazone for type 2 diabetes mellitus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3668190

7 July 2018

Pharmacological regulation of insulin secretion in MIN6 cells through the fatty acid receptor GPR40: identification of agonist and antagonist small molecules

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3668190

7 July 2018

Role of GPR40 in fatty acid action on the beta cell line INS-1E.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3668190

7 July 2018

Oleic acid interacts with GPR40 to induce Ca2+ signaling in rat islet beta-cells: mediation by PLC and L-type Ca2+ channel and link to insulin release

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3668190

7 July 2018

Use and abuse of HOMA modeling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3668190

7 July 2018

Potential role of peroxisome proliferator-activated receptor-alpha in the modulation of glucose-stimulated insulin secretion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3668190

7 July 2018

Loss of early insulin secretion leads to postprandial hyperglycaemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3668190

7 July 2018

Beta-cell lipotoxicity in the pathogenesis of non-insulin-dependent diabetes mellitus of obese rats: impairment in adipocyte-beta-cell relationships

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3668190

7 July 2018

Cell death: the significance of apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3668190

7 July 2018

Apoptosis: A Basic Biological Phenomenon with Wideranging Implications in Tissue Kinetics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3668190

7 July 2018

An interspecies comparison of normal levels of glycosylated hemoglobin and glycosylated albumin.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3668190

7 July 2018

Antilipolytic action of insulin in adipocytes from starved and diabetic rats during adenosine-controlled incubations.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3668190

7 July 2018

Identifying and Quantifying Apoptosis: Navigating Technical Pitfalls

1 reference

https://api.crossref.org/works/10.1186%2F2050-6511-14-28

21 January 2018

Increased pancreatic beta-cell apoptosis following fetal and neonatal exposure to nicotine is mediated via the mitochondria

1 reference

https://api.crossref.org/works/10.1186%2F2050-6511-14-28

21 January 2018

Free fatty acid as a link in the regulation of hepatic glucose output by peripheral insulin

1 reference

https://api.crossref.org/works/10.1186%2F2050-6511-14-28

21 January 2018

Effect of a sustained reduction in plasma free fatty acid concentration on intramuscular long-chain fatty Acyl-CoAs and insulin action in type 2 diabetic patients

1 reference

https://api.crossref.org/works/10.1186%2F2050-6511-14-28

21 January 2018

Involvement of thioredoxin-interacting protein (TXNIP) in glucocorticoid-mediated beta cell death

1 reference

https://api.crossref.org/works/10.1186%2F2050-6511-14-28

21 January 2018

Rosiglitazone prevents the onset of hyperglycaemia and proteinuria in the Zucker diabetic fatty rat.

1 reference

https://api.crossref.org/works/10.1186%2F2050-6511-14-28

21 January 2018

Chronic inhibition of circulating dipeptidyl peptidase IV by FE 999011 delays the occurrence of diabetes in male zucker diabetic fatty rats

1 reference

https://api.crossref.org/works/10.1186%2F2050-6511-14-28

21 January 2018

An ultrastructural description of the cell types in the endocrine pancreas of the pigeon

1 reference

https://pubmed.ncbi.nlm.nih.gov/23692921

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prevention of hyperglycemia in the Zucker diabetic fatty rat by treatment with metformin or troglitazone

1 reference

https://pubmed.ncbi.nlm.nih.gov/23692921

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The correlative light and electron microscopy of the islets of Langerhans in some lower vertebrates

1 reference

https://pubmed.ncbi.nlm.nih.gov/23692921

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Administration of phytosterols isolated from Aloe vera gel reduce visceral fat mass and improve hyperglycemia in Zucker diabetic fatty (ZDF) rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/23692921

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TAK-875 versus placebo or glimepiride in type 2 diabetes mellitus: a phase 2, randomised, double-blind, placebo-controlled trial

1 reference

https://pubmed.ncbi.nlm.nih.gov/23692921

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acute and chronic oral administration of bis(maltolato)oxovanadium(IV) in Zucker diabetic fatty (ZDF) rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/23692921

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of apoptosis in failure of beta-cell mass compensation for insulin resistance and beta-cell defects in the male Zucker diabetic fatty rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/23692921

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evolution of β-Cell Dysfunction in the Male Zucker Diabetic Fatty Rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/23692921

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1186/2050-6511-14-28

1 reference

Europe PubMed Central

4 August 2017

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0 references

1 reference

Europe PubMed Central

4 August 2017

1 reference

Europe PubMed Central

4 August 2017

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