(Q34732889)

4 August 2017

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title

Understanding Rho/Rac biology in T-cells using animal models (English)

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4 August 2017

Xosé R Bustelo

1

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language of work or name

English

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publication date

1 July 2002

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4 August 2017

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4 August 2017

volume

24

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4 August 2017

issue

7

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4 August 2017

page(s)

602-612

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Selection of the T cell repertoire.

4 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1002%2FBIES.10107

T cell activation and the cytoskeleton

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.10107

Molecular controls of antigen receptor clustering and autoimmunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.10107

The immunological synapse and the actin cytoskeleton: molecular hardware for T cell signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.10107

Rho GTPases and signaling networks

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.10107

Regulation of the cytoskeleton and cell adhesion by the Rho family GTPases in mammalian cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.10107

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.10107

Structure of the Rho family GTP-binding protein Cdc42 in complex with the multifunctional regulator RhoGDI

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.10107

The Rac-RhoGDI complex and the structural basis for the regulation of Rho proteins by RhoGDI

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.10107

Integrins regulate GTP-Rac localized effector interactions through dissociation of Rho-GDI

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.10107

Regulation of the polarization of T cells toward antigen-presenting cells by Ras-related GTPase CDC42

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.10107

Rac regulates integrin-mediated spreading and increased adhesion of T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.10107

Rho GTPases control migration and polarization of adhesion molecules and cytoskeletal ERM components in T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.10107

The interaction between Cdc42 and WASP is required for SDF-1-induced T-lymphocyte chemotaxis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.10107

Phosphotyrosine-dependent activation of Rac-1 GDP/GTP exchange by the vav proto-oncogene product

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.10107

Phosphorylation-dependent and constitutive activation of Rho proteins by wild-type and oncogenic Vav-2

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.10107

Biological and regulatory properties of Vav-3, a new member of the Vav family of oncoproteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.10107

Regulatory and signaling properties of the Vav family

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.10107

Product of vav proto-oncogene defines a new class of tyrosine protein kinase substrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.10107

Vav-2 controls NFAT-dependent transcription in B- but not T-lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.10107

Vav is a regulator of cytoskeletal reorganization mediated by the T-cell receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.10107

Defective T-cell receptor signalling and positive selection of Vav-deficient CD4+ CD8+ thymocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.10107

Defective antigen receptor-mediated proliferation of B and T cells in the absence of Vav.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.10107

Defective signalling through the T- and B-cell antigen receptors in lymphoid cells lacking the vav proto-oncogene

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.10107

Analysis of thymocyte development reveals that the GTPase RhoA is a positive regulator of T cell receptor responses in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.10107

The Rho-family GTP exchange factor Vav is a critical transducer of T cell receptor signals to the calcium, ERK, and NF-kappaB pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.10107

Defects in actin-cap formation in Vav-deficient mice implicate an actin requirement for lymphocyte signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.10107

CD19 as a membrane-anchored adaptor protein of B lymphocytes: costimulation of lipid and protein kinases by recruitment of Vav.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.10107

Vav3 modulates B cell receptor responses by regulating phosphoinositide 3-kinase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.10107

Vav regulates peptide-specific apoptosis in thymocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.10107

The protein kinase Pak3 positively regulates Raf-1 activity through phosphorylation of serine 338

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.10107

A Nck-Pak1 signaling module is required for T-cell receptor-mediated activation of NFAT, but not of JNK

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.10107

Pivotal role of phosphoinositide-3 kinase in regulation of cytotoxicity in natural killer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.10107

Actions of Rho family small G proteins and p21-activated protein kinases on mitogen-activated protein kinase family members

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.10107

T cells: getting a GRP on Ras.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.10107

Mutation in Sos1 dominantly enhances a weak allele of the EGFR, demonstrating a requirement for Sos1 in EGFR signaling and development

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.10107

Targeted disruption of Ras-Grf2 shows its dispensability for mouse growth and development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.10107

Deficiency of the hematopoietic cell-specific Rho family GTPase Rac2 is characterized by abnormalities in neutrophil function and host defense

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.10107

Deficiency of small GTPase Rac2 affects T cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.10107

Rac1 is required for the formation of three germ layers during gastrulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.10107

The GTPase Rho has a critical regulatory role in thymus development

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.10107

Bacterial protein toxins targeting rho GTPases

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.10107

The GTPase rho controls a p53-dependent survival checkpoint during thymopoiesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.10107

p56lck signals for regulating thymocyte development can be distinguished by their dependency on Rho function

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.10107

Cdc42 is required for PIP(2)-induced actin polymerization and early development but not for cell viability

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.10107

Increased neutrophil respiratory burst in bcr-null mutants

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.10107

Cbl-b, a member of the Sli-1/c-Cbl protein family, inhibits Vav-mediated c-Jun N-terminal kinase activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.10107

Cbl-b is a negative regulator of receptor clustering and raft aggregation in T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.10107

Cbl-b regulates the CD28 dependence of T-cell activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.10107

The Wiskott-Aldrich syndrome protein (WASP): roles in signaling and cytoskeletal organization

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.10107

Wiskott-Aldrich syndrome protein-deficient mice reveal a role for WASP in T but not B cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.10107

Selective modulation of protein kinase C-theta during T-cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.10107

Differential roles of ERK and p38 MAP kinase pathways in positive and negative selection of T lymphocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.10107

Differentiation of CD4+ T cells to Th1 cells requires MAP kinase JNK2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.10107

JNK is required for effector T-cell function but not for T-cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.10107

SEK1/MKK4 is required for maintenance of a normal peripheral lymphoid compartment but not for lymphocyte development

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.10107

Defective IL-12 production in mitogen-activated protein (MAP) kinase kinase 3 (Mkk3)-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.10107

Signal transduction through Vav-2 participates in humoral immune responses and B cell maturation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.10107

Defective T Cell Differentiation in the Absence of Jnk1

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.10107

PKC-θ is required for TCR-induced NF-κB activation in mature but not immature T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.10107

Negative regulation of lymphocyte activation and autoimmunity by the molecular adaptor Cbl-b

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.10107

21 January 2018

Identifiers

DOI

10.1002/BIES.10107

1 reference

4 August 2017

1 reference