(Q34747176)

4 August 2017

title

Transcription-coupled nucleotide excision repair factors promote R-loop-induced genome instability (English)

1 reference

4 August 2017

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María L García-Rubio

3

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Andrés Aguilera

object named as

Andrés Aguilera

5

0 references

author name string

Julie Sollier

1

1 reference

4 August 2017

Caroline Townsend Stork

2

1 reference

4 August 2017

Renee D Paulsen

4

1 reference

4 August 2017

Karlene A Cimprich

6

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4 August 2017

publication date

26 November 2014

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4 August 2017

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4 August 2017

volume

56

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4 August 2017

issue

6

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4 August 2017

page(s)

777-785

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A double-edged sword: R loops as threats to genome integrity and powerful regulators of gene expression

4 August 2017

cites work

1 reference

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R-loops associated with triplet repeat expansions promote gene silencing in Friedreich ataxia and fragile X syndrome.

7 July 2018

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The contribution of co-transcriptional RNA:DNA hybrid structures to DNA damage and genome instability

7 July 2018

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Transcription-associated R-loop formation across the human FMR1 CGG-repeat region

7 July 2018

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Genome-wide profiling of yeast DNA:RNA hybrid prone sites with DRIP-chip

7 July 2018

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C9orf72 nucleotide repeat structures initiate molecular cascades of disease.

7 July 2018

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Promoter-bound trinucleotide repeat mRNA drives epigenetic silencing in fragile X syndrome

7 July 2018

1 reference

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GC skew at the 5' and 3' ends of human genes links R-loop formation to epigenetic regulation and transcription termination

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4272638

Senataxin, defective in the neurodegenerative disorder ataxia with oculomotor apraxia 2, lies at the interface of transcription and the DNA damage response

7 July 2018

1 reference

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Senataxin associates with replication forks to protect fork integrity across RNA-polymerase-II-transcribed genes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4272638

R loops: from transcription byproducts to threats to genome stability

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4272638

R-loop formation is a distinctive characteristic of unmethylated human CpG island promoters

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4272638

R-loop-mediated genome instability in mRNA cleavage and polyadenylation mutants

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4272638

RNase H and multiple RNA biogenesis factors cooperate to prevent RNA:DNA hybrids from generating genome instability

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4272638

Collisions between replication and transcription complexes cause common fragile site instability at the longest human genes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4272638

R-loop-mediated genomic instability is caused by impairment of replication fork progression

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4272638

Human senataxin resolves RNA/DNA hybrids formed at transcriptional pause sites to promote Xrn2-dependent termination

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4272638

Regulation of endonuclease activity in human nucleotide excision repair

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4272638

Yeast Sen1 helicase protects the genome from transcription-associated instability.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4272638

Loss of Topoisomerase I leads to R-loop-mediated transcriptional blocks during ribosomal RNA synthesis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4272638

SF1 and SF2 helicases: family matters

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4272638

Topoisomerase I suppresses genomic instability by preventing interference between replication and transcription

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4272638

A genome-wide siRNA screen reveals diverse cellular processes and pathways that mediate genome stability

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4272638

Ataxia telangiectasia mutated activation by transcription- and topoisomerase I-induced DNA double-strand breaks

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4272638

The RNA binding protein RNPS1 alleviates ASF/SF2 depletion-induced genomic instability

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4272638

Cockayne syndrome A and B proteins differentially regulate recruitment of chromatin remodeling and repair factors to stalled RNA polymerase II in vivo

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4272638

Inactivation of the SR protein splicing factor ASF/SF2 results in genomic instability

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4272638

DNA/RNA helicase gene mutations in a form of juvenile amyotrophic lateral sclerosis (ALS4)

7 July 2018

1 reference

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Deficiency in the nuclease activity of xeroderma pigmentosum G in mice leads to hypersensitivity to UV irradiation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4272638

Growth retardation, early death, and DNA repair defects in mice deficient for the nucleotide excision repair enzyme XPF

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4272638

Cotranscriptionally Formed DNA:RNA Hybrids Mediate Transcription Elongation Impairment and Transcription-Associated Recombination

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4272638

R-loops at immunoglobulin class switch regions in the chromosomes of stimulated B cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4272638

Mechanisms of transcription-coupled DNA repair

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4272638

A protein complex containing Tho2, Hpr1, Mft1 and a novel protein, Thp2, connects transcription elongation with mitotic recombination in Saccharomyces cerevisiae

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4272638

Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4272638

Xeroderma pigmentosum group C protein complex is the initiator of global genome nucleotide excision repair

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4272638

Instability and decay of the primary structure of DNA

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4272638

Characterization of monoclonal antibody to DNA.RNA and its application to immunodetection of hybrids

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4272638

NER factors are recruited to active promoters and facilitate chromatin modification for transcription in the absence of exogenous genotoxic attack.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4272638

Replication fork progression is impaired by transcription in hyperrecombinant yeast cells lacking a functional THO complex

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4272638

AID binds to transcription-induced structures in c-MYC that map to regions associated with translocation and hypermutation

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4272638

Role of reciprocal exchange, one-ended invasion crossover and single-strand annealing on inverted and direct repeat recombination in yeast: different requirements for the RAD1, RAD10, and RAD52 genes

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4272638

Transcription-induced cleavage of immunoglobulin switch regions by nucleotide excision repair nucleases in vitro

26 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25435140

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Interdependence between Transcription and mRNP Processing and Export, and Its Impact on Genetic Stability

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25435140

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

A spliceosomal intron binding protein, IBP160, links position-dependent assembly of intron-encoded box C/D snoRNP to pre-mRNA splicing

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25435140

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.MOLCEL.2014.10.020

1 reference

4 August 2017

1 reference

4 August 2017

1 reference