(Q34750358)

4 August 2017

title

Intestinal epithelial cells as producers but not targets of chronic TNF suffice to cause murine Crohn-like pathology (English)

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4 August 2017

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Maria Armaka

2

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Giorgos Kollias

object named as

George Kollias

5

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author name string

Manolis Roulis

1

1 reference

4 August 2017

Menelaos Manoloukos

3

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4 August 2017

Maria Apostolaki

4

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4 August 2017

language of work or name

English

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publication date

14 March 2011

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Proceedings of the National Academy of Sciences of the United States of America

4 August 2017

published in

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4 August 2017

volume

108

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4 August 2017

issue

13

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4 August 2017

page(s)

5396-5401

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TNF suppresses acute intestinal inflammation by inducing local glucocorticoid synthesis

4 August 2017

cites work

1 reference

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Intestinal bacteria and the regulation of immune cell homeostasis

7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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Deletion polymorphism upstream of IRGM associated with altered IRGM expression and Crohn's disease

7 July 2018

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7 July 2018

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A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells

7 July 2018

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Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1beta production

7 July 2018

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XBP1 links ER stress to intestinal inflammation and confers genetic risk for human inflammatory bowel disease

7 July 2018

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Enterocyte-derived TAK1 signaling prevents epithelium apoptosis and the development of ileitis and colitis

7 July 2018

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7 July 2018

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7 July 2018

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Mesenchymal cell targeting by TNF as a common pathogenic principle in chronic inflammatory joint and intestinal diseases

7 July 2018

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7 July 2018

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7 July 2018

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Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis

7 July 2018

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Role of intestinal subepithelial myofibroblasts in inflammation and regenerative response in the gut.

7 July 2018

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Matrix metalloproteinases in inflammatory bowel disease: boon or a bane?

7 July 2018

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Molecular basis of epithelial barrier regulation: from basic mechanisms to clinical application

7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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TNF-alpha neutralization ameliorates the severity of murine Crohn's-like ileitis by abrogation of intestinal epithelial cell apoptosis

7 July 2018

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Genetic dissection of the cellular pathways and signaling mechanisms in modeled tumor necrosis factor-induced Crohn's-like inflammatory bowel disease

7 July 2018

1 reference

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Inflammatory Bowel Disease

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3069201

The immunology of mucosal models of inflammation

7 July 2018

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7 July 2018

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Mice deficient for the 55 kd tumor necrosis factor receptor are resistant to endotoxic shock, yet succumb to L. monocytogenes infection

7 July 2018

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A distinct array of proinflammatory cytokines is expressed in human colon epithelial cells in response to bacterial invasion

7 July 2018

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Role of beta7 integrin and the chemokine/chemokine receptor pair CCL25/CCR9 in modeled TNF-dependent Crohn's disease.

7 July 2018

1 reference

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FDC-specific functions of p55TNFR and IKK2 in the development of FDC networks and of antibody responses.

26 October 2018

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Nod2 mutation in Crohn's disease potentiates NF-kappaB activity and IL-1beta processing

26 October 2018

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Downregulation of epithelial apoptosis and barrier repair in active Crohn's disease by tumour necrosis factor alpha antibody treatment

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3069201

Activation of NF-kappaB in intestinal epithelial cells by E. coli strains isolated from the colonic mucosa of IBD patients

26 October 2018

1 reference

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Cis elements of the villin gene control expression in restricted domains of the vertical (crypt) and horizontal (duodenum, cecum) axes of the intestine.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3069201

A short-term study of chimeric monoclonal antibody cA2 to tumor necrosis factor alpha for Crohn's disease. Crohn's Disease cA2 Study Group.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3069201

TNF-induced enterocyte apoptosis in mice is mediated by the TNF receptor 1 and does not require p53

26 October 2018

1 reference

12 December 2020

Impaired On/Off Regulation of TNF Biosynthesis in Mice Lacking TNF AU-Rich Elements

1 reference

12 December 2020

Critical role of cAMP response element binding protein expression in hypoxia-elicited induction of epithelial tumor necrosis factor-alpha.

1 reference

12 December 2020

Matrix metalloproteinase levels are elevated in inflammatory bowel disease

1 reference

12 December 2020

Subepithelial myofibroblasts are novel nonprofessional APCs in the human colonic mucosa

1 reference

12 December 2020

Epithelial NEMO links innate immunity to chronic intestinal inflammation

1 reference

12 December 2020

Functional modulation of Crohn's disease myofibroblasts by anti-tumor necrosis factor antibodies

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.1007811108

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4 August 2017

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4 August 2017

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