(Q34752088)

4 August 2017

title

Multiple functional therapeutic effects of the estrogen receptor β agonist indazole-Cl in a mouse model of multiple sclerosis (English)

1 reference

4 August 2017

0 references

1 reference

Spencer M Moore

1

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author name string

Anna J Khalaj

2

1 reference

4 August 2017

Shalini Kumar

3

1 reference

4 August 2017

Zachary Winchester

4

1 reference

4 August 2017

JaeHee Yoon

5

1 reference

4 August 2017

Timothy Yoo

6

1 reference

4 August 2017

Leonardo Martinez-Torres

7

1 reference

4 August 2017

Norio Yasui

8

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4 August 2017

John A Katzenellenbogen

9

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4 August 2017

Seema Kaushalya Tiwari-Woodruff

10

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4 August 2017

language of work or name

English

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publication date

1 December 2014

1 reference

Proceedings of the National Academy of Sciences of the United States of America

4 August 2017

published in

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4 August 2017

volume

111

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4 August 2017

issue

50

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4 August 2017

page(s)

18061-18066

1 reference

Therapeutic laquinimod treatment decreases inflammation, initiates axon remyelination, and improves motor deficit in a mouse model of multiple sclerosis

4 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273334

Estrogen receptor (ER) β expression in oligodendrocytes is required for attenuation of clinical disease by an ERβ ligand

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273334

Estrogen receptors (ERα versus ERβ): friends or foes in human biology?

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273334

Estrogen receptor β ligand therapy activates PI3K/Akt/mTOR signaling in oligodendrocytes and promotes remyelination in a mouse model of multiple sclerosis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273334

Sex chromosome complement influences functional callosal myelination

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273334

Targeting estrogen receptor β in microglia and T cells to treat experimental autoimmune encephalomyelitis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273334

Passive experimental autoimmune encephalomyelitis in C57BL/6 with MOG: evidence of involvement of B cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273334

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273334

An ADIOL-ERβ-CtBP transrepression pathway negatively regulates microglia-mediated inflammation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273334

An animal model of cortical and callosal pathology in multiple sclerosis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273334

Activated microglia mediate axoglial disruption that contributes to axonal injury in multiple sclerosis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273334

MRI of the corpus callosum in multiple sclerosis: association with disability

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273334

Akt signals through the mammalian target of rapamycin pathway to regulate CNS myelination.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273334

Remyelination in the CNS: from biology to therapy

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273334

Constitutively active Akt induces enhanced myelination in the CNS

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273334

Multiple sclerosis: an immune or neurodegenerative disorder?

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273334

The role of SVZ-derived neural precursors in demyelinating diseases: from animal models to multiple sclerosis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273334

Differential neuroprotective and antiinflammatory effects of estrogen receptor (ER)alpha and ERbeta ligand treatment

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273334

Indazole estrogens: highly selective ligands for the estrogen receptor beta.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273334

Treatment of multiple sclerosis with the pregnancy hormone estriol

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273334

Caspase-11 mediates oligodendrocyte cell death and pathogenesis of autoimmune-mediated demyelination

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273334

Multiple sclerosis and chronic autoimmune encephalomyelitis: a comparative quantitative study of axonal injury in active, inactive, and remyelinated lesions

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273334

Estrogen potentiates treatment with T-cell receptor protein of female mice with experimental encephalomyelitis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273334

The pathophysiology of multiple sclerosis: the mechanisms underlying the production of symptoms and the natural history of the disease

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273334

Interhemispheric inhibition in patients with multiple sclerosis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4273334

Oligodendrocyte progenitors are present in the normal adult human CNS and in the lesions of multiple sclerosis

7 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1411294111

Oestrogen receptor β ligand: a novel treatment to enhance endogenous functional remyelination

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1411294111

Assaying the functional effects of demyelination and remyelination: revisiting field potential recordings

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1411294111

IGF-1-stimulated protein synthesis in oligodendrocyte progenitors requires PI3K/mTOR/Akt and MEK/ERK pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1411294111

Contribution of cortical and white matter lesions to cognitive impairment in multiple sclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1411294111

Functional recovery of callosal axons following demyelination: a critical window

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1411294111

The oligodendrocyte-type-2 astrocyte cell lineage is specialized for myelination

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1411294111

Estrogen Receptor (ER)-β Reduces ERα-Regulated Gene Transcription, Supporting a “Ying Yang” Relationship between ERα and ERβ in Mice

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25453074

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Estrogen-induced keratinocyte growth factor mRNA expression in normal and cancerous human breast cells

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25453074

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.1411294111

1 reference

4 August 2017

0 references

1 reference

4 August 2017

1 reference