(Q37377107)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19474313%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

title

Akt signals through the mammalian target of rapamycin pathway to regulate CNS myelination (English)

1 reference

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29 January 2020

1 reference

1 reference

1

1 reference

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29 January 2020

4

Wendy B Macklin

1 reference

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29 January 2020

author name string

Ana I Flores

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19474313%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

Feng Wang

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19474313%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

language of work or name

English

0 references

publication date

1 May 2009

1 reference

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29 January 2020

published in

Journal of Neuroscience

1 reference

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29 January 2020

volume

29

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19474313%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

issue

21

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19474313%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

page(s)

6860-6870

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19474313%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

29 January 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2757755/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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Constitutively active Akt induces enhanced myelination in the CNS

6 September 2017

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6 September 2017

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Response of a neuronal model of tuberous sclerosis to mammalian target of rapamycin (mTOR) inhibitors: effects on mTORC1 and Akt signaling lead to improved survival and function

6 September 2017

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The potential role of histone deacetylase inhibitors in the treatment of non-small-cell lung cancer

6 September 2017

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6 September 2017

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6 September 2017

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A randomized, phase II trial of two dose levels of temsirolimus (CCI-779) in patients with extensive-stage small-cell lung cancer who have responding or stable disease after induction chemotherapy: a trial of the Eastern Cooperative Oncology Group (

6 September 2017

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Role of mTOR in physiology and pathology of the nervous system

6 September 2017

1 reference

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IGF-1 protects oligodendrocyte progenitors against TNFalpha-induced damage by activation of PI3K/Akt and interruption of the mitochondrial apoptotic pathway.

6 September 2017

1 reference

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A mouse model of tuberous sclerosis: neuronal loss of Tsc1 causes dysplastic and ectopic neurons, reduced myelination, seizure activity, and limited survival

6 September 2017

1 reference

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Mammalian target of rapamycin: master regulator of cell growth in the nervous system

6 September 2017

1 reference

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mTOR Complex1-S6K1 signaling: at the crossroads of obesity, diabetes and cancer

6 September 2017

1 reference

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6 September 2017

The two TORCs and Akt.

1 reference

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mTOR, translation initiation and cancer

6 September 2017

1 reference

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mSin1 is necessary for Akt/PKB phosphorylation, and its isoforms define three distinct mTORC2s

6 September 2017

1 reference

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An oligodendrocyte-specific zinc-finger transcription regulator cooperates with Olig2 to promote oligodendrocyte differentiation

6 September 2017

1 reference

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Ribosomal protein S6 phosphorylation: from protein synthesis to cell size.

6 September 2017

1 reference

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Prolonged rapamycin treatment inhibits mTORC2 assembly and Akt/PKB

6 September 2017

1 reference

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Akt1 in endothelial cell and angiogenesis

6 September 2017

1 reference

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Fibronectin stimulates non-small cell lung carcinoma cell growth through activation of Akt/mammalian target of rapamycin/S6 kinase and inactivation of LKB1/AMP-activated protein kinase signal pathways

6 September 2017

1 reference

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Targeting the phosphatidylinositol-3 kinase/Akt pathway for the treatment of cancer

6 September 2017

1 reference

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Inhibitors of the mammalian target of rapamycin

6 September 2017

1 reference

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Sirolimus for Kaposi's sarcoma in renal-transplant recipients

6 September 2017

1 reference

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Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex

6 September 2017

1 reference

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Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive

6 September 2017

1 reference

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Advances in protein kinase B signalling: AKTion on multiple fronts

6 September 2017

1 reference

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6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757755

mTor is required for hypertrophy of Pten-deficient neuronal soma in vivo

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757755

In vivo expression and regulation of Elk-1, a target of the extracellular-regulated kinase signaling pathway, in the adult rat brain

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757755

Differentiation and death of premyelinating oligodendrocytes in developing rodent brain

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757755

Myostatin induces cyclin D1 degradation to cause cell cycle arrest through a phosphatidylinositol 3-kinase/AKT/GSK-3 beta pathway and is antagonized by insulin-like growth factor 1.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757755

Constitutively active Akt1 expression in mouse pancreas requires S6 kinase 1 for insulinoma formation

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757755

Combinatorial profiles of oligodendrocyte-selective classes of transcriptional regulators differentially modulate myelin basic protein gene expression.

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757755

Mammalian target of rapamycin (mTOR) is activated in cutaneous vascular malformations in vivo

26 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757755

PRR5, a novel component of mTOR complex 2, regulates platelet-derived growth factor receptor beta expression and signaling.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757755

Rapamycin is a neuroprotective treatment for traumatic brain injury.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757755

Induction of oligodendrocyte differentiation by Olig2 and Sox10: evidence for reciprocal interactions and dosage-dependent mechanisms.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757755

Phase II trial of temsirolimus (CCI-779) in recurrent glioblastoma multiforme: a North Central Cancer Treatment Group Study

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757755

Proteolipid promoter activity distinguishes two populations of NG2-positive cells throughout neonatal cortical development.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757755

The bHLH transcription factor Olig2 promotes oligodendrocyte differentiation in collaboration with Nkx2.2.

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757755

Loss of p27Kip1 function results in increased proliferative capacity of oligodendrocyte progenitors but unaltered timing of differentiation

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757755

Akt-mediated survival of oligodendrocytes induced by neuregulins.

2 September 2018

1 reference

12 December 2020

Dual origin of spinal oligodendrocyte progenitors and evidence for the cooperative role of Olig2 and Nkx2.2 in the control of oligodendrocyte differentiation

1 reference

12 December 2020

Protection of p27(Kip1) mRNA by quaking RNA binding proteins promotes oligodendrocyte differentiation

1 reference

12 December 2020

Synergistic induction of cyclin D1 in oligodendrocyte progenitor cells by IGF-I and FGF-2 requires differential stimulation of multiple signaling pathways

1 reference

12 December 2020

Activation of the mammalian target of rapamycin (mTOR) is essential for oligodendrocyte differentiation

1 reference

12 December 2020

10.1523/JNEUROSCI.0232-09.2009

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19474313%20AND%20SRC:MED&resulttype=core&format=json

release_5lhma2b2qneqreequnz2swhngm

29 January 2020

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/5lhma2b2qneqreequnz2swhngm

24 November 2022

mapped directly with Wikidata item

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19474313%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

PubMed publication ID

19474313

1 reference