(Q34761229)

4 August 2017

title

Neuroprotective efficacy of a new brain-penetrating C-Abl inhibitor in a murine Parkinson's disease model (English)

1 reference

4 August 2017

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Syed Z Imam

1

1 reference

4 August 2017

William Trickler

2

1 reference

4 August 2017

Shinya Kimura

3

1 reference

4 August 2017

Zbigniew K Binienda

4

1 reference

4 August 2017

Merle G Paule

5

1 reference

4 August 2017

William Slikker

6

1 reference

4 August 2017

Senlin Li

7

1 reference

4 August 2017

Robert A Clark

8

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4 August 2017

Syed F Ali

9

1 reference

4 August 2017

language of work or name

English

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publication date

31 May 2013

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4 August 2017

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4 August 2017

volume

8

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4 August 2017

issue

5

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4 August 2017

page(s)

e65129

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Creative Commons CC0 License

4 August 2017

copyright license

start time

31 May 2013

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted, dedicated to the public domain by copyright holder

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describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3669292/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Novel regulation of parkin function through c-Abl-mediated tyrosine phosphorylation: implications for Parkinson's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3669292

Bafetinib, a dual Bcr-Abl/Lyn tyrosine kinase inhibitor for the potential treatment of leukemia

7 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3669292

Phase 1 study of INNO-406, a dual Abl/Lyn kinase inhibitor, in Philadelphia chromosome-positive leukemias after imatinib resistance or intolerance

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3669292

Deregulation of proteasome function induces Abl-mediated cell death by uncoupling p130CAS and c-CrkII.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3669292

Dopamine covalently modifies and functionally inactivates parkin

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3669292

NS-187, a potent and selective dual Bcr-Abl/Lyn tyrosine kinase inhibitor, is a novel agent for imatinib-resistant leukemia

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3669292

Tyrosine 394 is phosphorylated in Alzheimer's paired helical filament tau and in fetal tau with c-Abl as the candidate tyrosine kinase.

7 July 2018

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Activation of the neuronal c-Abl tyrosine kinase by amyloid-beta-peptide and reactive oxygen species

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3669292

S-nitrosylation of parkin regulates ubiquitination and compromises parkin's protective function

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3669292

Regulation of the c-Abl and Bcr-Abl tyrosine kinases

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3669292

Molecular Pathways of Neurodegeneration in Parkinson's Disease

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3669292

Parkinson's disease: mechanisms and models

7 July 2018

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Aging increases the susceptiblity to methamphetamine-induced dopaminergic neurotoxicity in rats: correlation with peroxynitrite production and hyperthermia

7 July 2018

1 reference

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Structural mechanism for STI-571 inhibition of abelson tyrosine kinase

7 July 2018

1 reference

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Association between early-onset Parkinson's disease and mutations in the parkin gene

7 July 2018

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Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism

7 July 2018

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Role of neuronal nitric oxide in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced dopaminergic neurotoxicity

7 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3669292

Bovine brain microvessel endothelial cell monolayers as a model system for the blood-brain barrier

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3669292

A new diffusion chamber system for the determination of drug permeability coefficients across the human intestinal epithelium that are independent of the unstirred water layer

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3669292

New developments in understanding the etiology of Parkinson's disease and in its treatment

7 July 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0065129

Microelectrode recordings define the ventral posteromedial pallidotomy target

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0065129

Drug efflux transport properties of 2',7'-bis(2-carboxyethyl)-5(6)-carboxyfluorescein acetoxymethyl ester (BCECF-AM) and its fluorescent free acid, BCECF.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0065129

Brain microvessel endothelial cell responses to tumor necrosis factor-alpha involve a nuclear factor kappa B (NF-kappaB) signal transduction pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0065129

Activation of the cytoplasmic c-Abl tyrosine kinase by reactive oxygen species

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23741470

12 December 2020

inferred from PubMed ID database lookup

The effect of Bcrp1 (Abcg2) on the in vivo pharmacokinetics and brain penetration of imatinib mesylate (Gleevec): implications for the use of breast cancer resistance protein and P-glycoprotein inhibitors to enable the brain penetration of imatinib

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23741470

12 December 2020

inferred from PubMed ID database lookup

Oxidative damage in Parkinson's disease

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23741470

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1371/JOURNAL.PONE.0065129

1 reference

4 August 2017

0 references

1 reference

4 August 2017

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