(Q29619903)

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=14593166

30 April 2017

Molecular Pathways of Neurodegeneration in Parkinson's Disease (English)

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1087753

27 March 2024

1 reference

Ted M. Dawson

1

1 reference

Europe PubMed Central

PubMed ID

14593166

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14593166

27 March 2024

Valina L. Dawson

2

1 reference

Europe PubMed Central

PubMed ID

14593166

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14593166

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=14593166

27 March 2024

language of work or name

1 reference

30 April 2017

publication date

31 October 2003

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=14593166

full work available at URL

30 April 2017

https://www.science.org/doi/pdf/10.1126/science.1087753

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1087753

27 March 2024

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=14593166

30 April 2017

volume

302

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=14593166

30 April 2017

page(s)

819-22

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=14593166

30 April 2017

issue

5646

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=14593166

Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism

30 April 2017

cites work

1 reference

4 November 2023

https://opencitations.net/index/coci/api/v1/citations/10.1038/33416

Update on Parkinson disease

1

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1087753

Neuroprotective and neurorestorative strategies for Parkinson's disease

27 March 2024

2

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1087753

Staging of brain pathology related to sporadic Parkinson's disease

27 March 2024

3

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1087753

Neuropathology of Parkinson's disease

27 March 2024

4

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1087753

Alpha-synuclein and neurodegenerative diseases

27 March 2024

6

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1087753

Animal models of Parkinson's disease.

27 March 2024

7

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1087753

Genetic and environmental factors in the cause of Parkinson's disease

27 March 2024

8

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1087753

Experimental models of Parkinson's disease

27 March 2024

9

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1087753

Understanding cell death in Parkinson's disease.

27 March 2024

10

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1087753

Oxidative stress and genetics in the pathogenesis of Parkinson's disease

27 March 2024

11

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1087753

Environment, mitochondria, and Parkinson's disease

27 March 2024

12

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1087753

Mitochondria in the etiology and pathogenesis of parkinson's disease

27 March 2024

13

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1087753

Mitochondrial involvement in Parkinson's disease

27 March 2024

14

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1087753

Origin and functional consequences of the complex I defect in Parkinson's disease

27 March 2024

15

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1087753

Matrilineal inheritance of complex I dysfunction in a multigenerational Parkinson's disease family

27 March 2024

16

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1087753

Mitochondrial Polymorphisms Significantly Reduce the Risk of Parkinson Disease

27 March 2024

17

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1087753

Targeting programmed cell death in neurodegenerative diseases

27 March 2024

18

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1087753

An electron microscopic study of MPTP-induced inclusion bodies in an old monkey

27 March 2024

19

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1087753

The nigrostriatal dopaminergic system as a preferential target of repeated exposures to combined paraquat and maneb: implications for Parkinson's disease.

27 March 2024

21

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1087753

The herbicide paraquat causes up-regulation and aggregation of alpha-synuclein in mice: paraquat and alpha-synuclein

27 March 2024

22

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1087753

Subcutaneous rotenone exposure causes highly selective dopaminergic degeneration and alpha-synuclein aggregation.

27 March 2024

23

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1087753

An in vitro model of Parkinson's disease: linking mitochondrial impairment to altered alpha-synuclein metabolism and oxidative damage.

27 March 2024

24

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1087753

Chronic systemic pesticide exposure reproduces features of Parkinson's disease

27 March 2024

25

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1087753

Neuroinflammatory processes in Parkinson's disease.

27 March 2024

26

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1087753

27 March 2024

From entropy to Duino

27

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1087753

Mutation in the alpha-synuclein gene identified in families with Parkinson's disease

27 March 2024

28

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1087753

Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease

27 March 2024

29

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1087753

alpha-Synuclein locus triplication causes Parkinson's disease

27 March 2024

30

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1087753

alpha-synuclein gene haplotypes are associated with Parkinson's disease

27 March 2024

31

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1087753

27 March 2024

32

3

REVIEWS3002

2002

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1087753

A hydrophobic stretch of 12 amino acid residues in the middle of alpha-synuclein is essential for filament assembly.

27 March 2024

33

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1087753

Exposure to long chain polyunsaturated fatty acids triggers rapid multimerization of synucleins.

27 March 2024

34

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1087753

The formation of highly soluble oligomers of alpha-synuclein is regulated by fatty acids and enhanced in Parkinson's disease

27 March 2024

35

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1087753

Animal models of PD: pieces of the same puzzle?

27 March 2024

36

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1087753

Neuronal alpha-synucleinopathy with severe movement disorder in mice expressing A53T human alpha-synuclein.

27 March 2024

37

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1087753

Human alpha-synuclein-harboring familial Parkinson's disease-linked Ala-53 --> Thr mutation causes neurodegenerative disease with alpha-synuclein aggregation in transgenic mice

27 March 2024

38

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1087753

Initiation and Synergistic Fibrillization of Tau and Alpha-Synuclein

27 March 2024

39

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1087753

Association of single-nucleotide polymorphisms of the tau gene with late-onset Parkinson disease

27 March 2024

40

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1087753

Dopaminergic loss and inclusion body formation in alpha-synuclein mice: implications for neurodegenerative disorders

27 March 2024

41

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1087753

Genetics of Parkinson's disease and biochemical studies of implicated gene products

27 March 2024

42

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1087753

beta-Synuclein inhibits alpha-synuclein aggregation: a possible role as an anti-parkinsonian factor

27 March 2024

43

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1087753

Kinetic stabilization of the alpha-synuclein protofibril by a dopamine-alpha-synuclein adduct

27 March 2024

44

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1087753

A Drosophila model of Parkinson's disease

27 March 2024

45

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1087753

Selective insolubility of alpha-synuclein in human Lewy body diseases is recapitulated in a transgenic mouse model

27 March 2024

46

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1087753

Misfolded proteinase K-resistant hyperphosphorylated alpha-synuclein in aged transgenic mice with locomotor deterioration and in human alpha-synucleinopathies

27 March 2024

47

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1087753

beta-amyloid peptides enhance alpha-synuclein accumulation and neuronal deficits in a transgenic mouse model linking Alzheimer's disease and Parkinson's disease

27 March 2024

48

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1087753

Oxidative stress and nitration in neurodegeneration: cause, effect, or association?

27 March 2024

49

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1087753

Biochemical analysis of cybrids expressing mitochondrial DNA from Contursi kindred Parkinson's subjects

27 March 2024

51

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1087753

Resistance of alpha -synuclein null mice to the parkinsonian neurotoxin MPTP.

27 March 2024

52

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1087753

Proteolytic stress: a unifying concept for the etiopathogenesis of Parkinson's disease

27 March 2024

54

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1087753

Chaperone suppression of alpha-synuclein toxicity in a Drosophila model for Parkinson's disease

27 March 2024

55

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1087753

Pharmacological prevention of Parkinson disease in Drosophila.

27 March 2024

56

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1087753

The 1.6-A crystal structure of the class of chaperones represented by Escherichia coli Hsp31 reveals a putative catalytic triad

27 March 2024

57

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1087753

The ubiquitin pathway in Parkinson's disease.

27 March 2024

59

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1087753

Parkin functions as an E2-dependent ubiquitin- protein ligase and promotes the degradation of the synaptic vesicle-associated protein, CDCrel-1

27 March 2024

61

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1087753

Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase

27 March 2024

62

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1087753

Mechanisms underlying ubiquitination

27 March 2024

63

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1087753

Parkin: a multipurpose neuroprotective agent?

27 March 2024

64

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1087753

Mitochondrial pathology and apoptotic muscle degeneration in Drosophila parkin mutants

27 March 2024

65

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1087753

Parkin ubiquitinates the alpha-synuclein-interacting protein, synphilin-1: implications for Lewy-body formation in Parkinson disease

27 March 2024

66

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1087753

Ubiquitination of a new form of alpha-synuclein by parkin from human brain: implications for Parkinson's disease

27 March 2024

67

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1087753

Parkin protects against the toxicity associated with mutant alpha-synuclein: proteasome dysfunction selectively affects catecholaminergic neurons

27 March 2024

68

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1087753

Parkin suppresses dopaminergic neuron-selective neurotoxicity induced by Pael-R in Drosophila

27 March 2024

69

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1087753

Proteasome inhibition causes nigral degeneration with inclusion bodies in rats

27 March 2024

70

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1087753

Inducible expression of mutant alpha-synuclein decreases proteasome activity and increases sensitivity to mitochondria-dependent apoptosis

27 March 2024

71

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1087753

Expression of A53T mutant but not wild-type alpha-synuclein in PC12 cells induces alterations of the ubiquitin-dependent degradation system, loss of dopamine release, and autophagic cell death.

27 March 2024

72

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1087753

Aggregated and monomeric alpha-synuclein bind to the S6' proteasomal protein and inhibit proteasomal function

27 March 2024

73

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1087753

A susceptibility locus for Parkinson's disease maps to chromosome 2p13.

27 March 2024

74

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1087753

Localization of a novel locus for autosomal recessive early-onset parkinsonism, PARK6, on human chromosome 1p35-p36

27 March 2024

75

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1087753

Mutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonism

27 March 2024

76

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1087753

A new locus for Parkinson's disease (PARK8) maps to chromosome 12p11.2-q13.1.

27 March 2024

77

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1087753

Kufor-Rakeb syndrome, pallido-pyramidal degeneration with supranuclear upgaze paresis and dementia, maps to 1p36

27 March 2024

78

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1087753

A susceptibility gene for late-onset idiopathic Parkinson's disease

27 March 2024

79

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1087753

Mutations in NR4A2 associated with familial Parkinson disease

27 March 2024

80

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1087753

Identification and functional characterization of a novel R621C mutation in the synphilin-1 gene in Parkinson's disease

27 March 2024

81

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1087753

27 March 2024

Identifiers

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=14593166

30 April 2017

Consolidated OpenCitations Corpus – April 2017

771605

771605

1 reference

Consolidated OpenCitations Corpus – April 2017

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=14593166

2 references

30 April 2017

Consolidated OpenCitations Corpus – April 2017