(Q34982296)

5 August 2017

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title

Neuroprotective and neurorestorative strategies for Parkinson's disease (English)

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5 August 2017

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1

Ted M Dawson

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5 August 2017

Valina L Dawson

2

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PubMed ID

12403986

5 August 2017

language of work or name

English

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publication date

1 November 2002

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5 August 2017

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5 August 2017

5 Suppl

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5 August 2017

1058-1061

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https://scigraph.springernature.com/pub.10.1038/nn941

5 August 2017

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cites work

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7 January 2021

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Parkin and Parkinson's disease

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Prospects for new restorative and neuroprotective treatments in Parkinson's disease

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The role of the ubiquitin-proteasomal pathway in Parkinson's disease and other neurodegenerative disorders

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A mutation in the human neurofilament M gene in Parkinson's disease that suggests a role for the cytoskeleton in neuronal degeneration

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Fatal attractions: abnormal protein aggregation and neuron death in Parkinson's disease and Lewy body dementia

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Oxidative stress and genetics in the pathogenesis of Parkinson's disease

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Chronic systemic pesticide exposure reproduces features of Parkinson's disease

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7 January 2021

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7 January 2021

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Genetics of Parkinson's disease and biochemical studies of implicated gene products

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Kinetic stabilization of the alpha-synuclein protofibril by a dopamine-alpha-synuclein adduct

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7 January 2021

beta-Synuclein inhibits alpha-synuclein aggregation: a possible role as an anti-parkinsonian factor

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7 January 2021

Biophysical properties of the synucleins and their propensities to fibrillate: inhibition of alpha-synuclein assembly by beta- and gamma-synucleins

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7 January 2021

Chaperone suppression of alpha-synuclein toxicity in a Drosophila model for Parkinson's disease

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Modelling neurodegenerative diseases in Drosophila: a fruitful approach?

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Human alpha-synuclein-harboring familial Parkinson's disease-linked Ala-53 --> Thr mutation causes neurodegenerative disease with alpha-synuclein aggregation in transgenic mice

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Secretase as a target for Alzheimer's disease

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alpha-Synuclein is phosphorylated in synucleinopathy lesions

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An unfolded putative transmembrane polypeptide, which can lead to endoplasmic reticulum stress, is a substrate of Parkin

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7 January 2021

Neuroprotective and neurorestorative properties of GDNF.

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7 January 2021

Neurodegeneration prevented by lentiviral vector delivery of GDNF in primate models of Parkinson's disease

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7 January 2021

Parkinson disease gene therapy moves toward the clinic

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7 January 2021

New treatment improves symptoms of Parkinson's disease

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Grafting of encapsulated genetically modified cells secreting GDNF into the striatum of parkinsonian model rats.

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7 January 2021

Building animals from stem cells

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Opinion: neural stem cell therapy for neurological diseases: dreams and reality

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7 January 2021

Cell therapy in Parkinson's disease - stop or go?

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7 January 2021

Embryonic stem cells develop into functional dopaminergic neurons after transplantation in a Parkinson rat model

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7 January 2021

Dopamine neurons derived from embryonic stem cells function in an animal model of Parkinson's disease.

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7 January 2021

Identifiers

DOI

10.1038/NN941

1 reference

5 August 2017

1 reference

PubMed ID

12403986