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Nociceptin/orphanin FQ receptor blockade attenuates MPTP-induced parkinsonism.
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Europe PubMed Central
PMC publication ID
2605654
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18413287%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 January 2020
title
Nociceptin/orphanin FQ receptor blockade attenuates MPTP-induced parkinsonism
(English)
1 reference
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Europe PubMed Central
PMC publication ID
2605654
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18413287%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 January 2020
main subject
nociceptin
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Parkinson's disease
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inferred from title
author
Riccardo Viaro
series ordinal
1
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Europe PubMed Central
PMC publication ID
2605654
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18413287%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 January 2020
Rosario Sanchez-Pernaute
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2
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Europe PubMed Central
PMC publication ID
2605654
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18413287%20AND%20SRC:MED&resulttype=core&format=json
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5 January 2020
Matteo Marti
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3
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PMC publication ID
2605654
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18413287%20AND%20SRC:MED&resulttype=core&format=json
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5 January 2020
Claudio Trapella
series ordinal
4
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Europe PubMed Central
PMC publication ID
2605654
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18413287%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 January 2020
Ole Isacson
series ordinal
5
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Europe PubMed Central
PMC publication ID
2605654
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18413287%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 January 2020
author name string
Michele Morari
series ordinal
6
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Europe PubMed Central
PMC publication ID
2605654
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18413287%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 January 2020
publication date
8 March 2008
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2605654
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18413287%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 January 2020
published in
Neurobiology of Disease
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Europe PubMed Central
PMC publication ID
2605654
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18413287%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 January 2020
volume
30
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Europe PubMed Central
PMC publication ID
2605654
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18413287%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 January 2020
issue
3
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Europe PubMed Central
PMC publication ID
2605654
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18413287%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 January 2020
page(s)
430-438
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Europe PubMed Central
PMC publication ID
2605654
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18413287%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 January 2020
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Europe PubMed Central
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11 June 2022
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https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2605654/fullTextXML
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cites work
In vivo evidence of D3 dopamine receptor sensitization in parkinsonian primates and rodents with l-DOPA-induced dyskinesias
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2605654
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7 July 2018
Protocol for the MPTP mouse model of Parkinson's disease
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2605654
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7 July 2018
Pharmacological characterization of the nociceptin/orphanin FQ receptor antagonist SB-612111 [(-)-cis-1-methyl-7-[[4-(2,6-dichlorophenyl)piperidin-1-yl]methyl]-6,7,8,9-tetrahydro-5H-benzocyclohepten-5-ol]: in vivo studies.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2605654
retrieved
7 July 2018
Nociceptin/orphanin FQ peptide receptors: pharmacology and clinical implications
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2605654
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7 July 2018
Behavioral models of Parkinson's disease in rodents: a new look at an old problem
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2605654
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7 July 2018
Effects of intrathecally administered nociceptin/orphanin FQ in monkeys: behavioral and mass spectrometric studies.
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PubMed Central
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7 July 2018
Characterization of the nociceptin receptor (ORL-1) agonist, Ro64-6198, in tests of anxiety across multiple species
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2605654
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7 July 2018
Mapping dopamine function in primates using pharmacologic magnetic resonance imaging
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2605654
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7 July 2018
The NOP (ORL1) receptor antagonist Compound B stimulates mesolimbic dopamine release and is rewarding in mice by a non-NOP-receptor-mediated mechanism
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2605654
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7 July 2018
Blockade of nociceptin/orphanin FQ receptor signaling in rat substantia nigra pars reticulata stimulates nigrostriatal dopaminergic transmission and motor behavior.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2605654
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7 July 2018
Evidence in locomotion test for the functional heterogeneity of ORL-1 receptors
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7 July 2018
Parkinson's disease: mechanisms and models
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PubMed Central
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7 July 2018
[Nphe1,Arg14,Lys15]nociceptin-NH2, a novel potent and selective antagonist of the nociceptin/orphanin FQ receptor.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2605654
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7 July 2018
Behavioral phenotyping of the MPTP mouse model of Parkinson's disease
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2605654
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7 July 2018
A synthetic agonist at the orphanin FQ/nociceptin receptor ORL1: anxiolytic profile in the rat.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2605654
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7 July 2018
Discovery of the first potent and selective small molecule opioid receptor-like (ORL1) antagonist: 1-[(3R,4R)-1-cyclooctylmethyl-3- hydroxymethyl-4-piperidyl]-3-ethyl-1, 3-dihydro-2H-benzimidazol-2-one (J-113397)
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PubMed Central
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7 July 2018
An automated rotarod method for quantitative drug-free evaluation of overall motor deficits in rat models of parkinsonism
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7 July 2018
Unrestrained nociceptive response and disregulation of hearing ability in mice lacking the nociceptin/orphaninFQ receptor
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2605654
retrieved
7 July 2018
Nociceptin stimulates locomotion and exploratory behaviour in mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2605654
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7 July 2018
Rats rapidly develop tolerance to the locomotor-inhibiting effects of the novel neuropeptide orphanin FQ.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2605654
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7 July 2018
NE-100, a novel sigma receptor ligand: effect on phencyclidine-induced behaviors in rats, dogs and monkeys
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2605654
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7 July 2018
Isolation and structure of the endogenous agonist of opioid receptor-like ORL1 receptor
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2605654
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7 July 2018
The catalepsy test: its ups and downs
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2605654
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7 July 2018
Protective action of neuronal nitric oxide synthase inhibitor in the MPTP mouse model of Parkinson's disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2605654
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26 October 2018
Effects of treadmill exercise on dopaminergic transmission in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned mouse model of basal ganglia injury.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2605654
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26 October 2018
The nociceptin/orphanin FQ receptor antagonist J-113397 and L-DOPA additively attenuate experimental parkinsonism through overinhibition of the nigrothalamic pathway.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2605654
retrieved
26 October 2018
Blockade of nociceptin/orphanin FQ transmission attenuates symptoms and neurodegeneration associated with Parkinson's disease.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2605654
retrieved
26 October 2018
Blockade of nociceptin/orphanin FQ transmission in rat substantia nigra reverses haloperidol-induced akinesia and normalizes nigral glutamate release
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2605654
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26 October 2018
Arundic acid, an astrocyte-modulating agent, protects dopaminergic neurons against MPTP neurotoxicity in mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2605654
retrieved
26 October 2018
Central administration of nociceptin/orphanin FQ blocks the acquisition of conditioned place preference to morphine and cocaine, but not conditioned place aversion to naloxone in mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2605654
retrieved
26 October 2018
Blockade of nociceptin/orphanin FQ-NOP receptor signalling produces antidepressant-like effects: pharmacological and genetic evidences from the mouse forced swimming test.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2605654
retrieved
26 October 2018
Autoradiographic localization of (125)i[Tyr(14)] nociceptin/orphanin FQ binding sites in macaque primate CNS.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2605654
retrieved
26 October 2018
Expression of orphanin FQ and the opioid receptor-like (ORL1) receptor in the developing human and rat brain
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2605654
retrieved
26 October 2018
MPTP susceptibility in the mouse: behavioral, neurochemical, and histological analysis of gender and strain differences.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2605654
retrieved
26 October 2018
Orphanin FQ: a neuropeptide that activates an opioidlike G protein-coupled receptor.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2605654
retrieved
26 October 2018
Identifiers
DOI
10.1016/J.NBD.2008.02.011
1 reference
stated in
Europe PubMed Central
PMC publication ID
2605654
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18413287%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 January 2020
PMC publication ID
2605654
1 reference
stated in
Europe PubMed Central
PMC publication ID
2605654
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18413287%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 January 2020
PubMed publication ID
18413287
1 reference
stated in
Europe PubMed Central
PMC publication ID
2605654
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18413287%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 January 2020
ResearchGate publication ID
5439926
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