(Q34778345)

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Cancer cells acquire a drug resistant, highly tumorigenic, cancer stem-like phenotype through modulation of the PI3K/Akt/β-catenin/CBP pathway.

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23784558%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

Cancer cells acquire a drug resistant, highly tumorigenic, cancer stem-like phenotype through modulation of the PI3K/Akt/β-catenin/CBP pathway (English)

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23784558%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

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3 March 2020

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Tong Xu

2

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3 March 2020

Yucheng Xu

3

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3 March 2020

Alexander Ring

4

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3 March 2020

Michael Kahn

5

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3 March 2020

Amir Goldkorn

6

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3 March 2020

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5 August 2013

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3 March 2020

International Journal of Cancer

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3 March 2020

134

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3 March 2020

1

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3 March 2020

43-54

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3 March 2020

Tumour stem cells and drug resistance

1 reference

https://api.crossref.org/works/10.1002%2FIJC.28341

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Stem cells, cancer, and cancer stem cells

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Treatment of radioresistant stem-like esophageal cancer cells by an apoptotic gene-armed, telomerase-specific oncolytic adenovirus

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PI3K pathway regulates survival of cancer stem cells residing in the perivascular niche following radiation in medulloblastoma in vivo

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Complex display of putative tumor stem cell markers in the NCI60 tumor cell line panel

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Cancer stem cells--perspectives on current status and future directions: AACR Workshop on cancer stem cells

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A cell initiating human acute myeloid leukaemia after transplantation into SCID mice

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Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell

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Efficient tumour formation by single human melanoma cells

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The epithelial-mesenchymal transition generates cells with properties of stem cells

1 reference

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21 January 2018

A chromatin-mediated reversible drug-tolerant state in cancer cell subpopulations

1 reference

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21 January 2018

Induction of pluripotent stem cells from adult human fibroblasts by defined factors

1 reference

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21 January 2018

Cancer cells cyclically lose and regain drug-resistant highly tumorigenic features characteristic of a cancer stem-like phenotype

1 reference

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21 January 2018

Normal and neoplastic nonstem cells can spontaneously convert to a stem-like state

1 reference

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21 January 2018

Targeting PI3K signalling in cancer: opportunities, challenges and limitations

1 reference

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21 January 2018

Activation of the PTEN/mTOR/STAT3 pathway in breast cancer stem-like cells is required for viability and maintenance

1 reference

https://api.crossref.org/works/10.1002%2FIJC.28341

21 January 2018

PTEN/PI3K/Akt pathway regulates the side population phenotype and ABCG2 activity in glioma tumor stem-like cells

1 reference

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21 January 2018

Combination therapy targeting both tumor-initiating and differentiated cell populations in prostate carcinoma

1 reference

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21 January 2018

Regulation of mammary stem/progenitor cells by PTEN/Akt/beta-catenin signaling

1 reference

https://api.crossref.org/works/10.1002%2FIJC.28341

21 January 2018

Reprogramming murine telomerase rapidly inhibits the growth of mouse cancer cells in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1002%2FIJC.28341

21 January 2018

The role of PTEN/Akt/PI3K signaling in the maintenance and viability of prostate cancer stem-like cell populations

1 reference

https://api.crossref.org/works/10.1002%2FIJC.28341

21 January 2018

PTEN can inhibit in vitro organotypic and in vivo orthotopic invasion of human bladder cancer cells even in the absence of its lipid phosphatase activity

1 reference

https://api.crossref.org/works/10.1002%2FIJC.28341

21 January 2018

Selective targeting of radiation-resistant tumor-initiating cells

1 reference

https://api.crossref.org/works/10.1002%2FIJC.28341

21 January 2018

Control of beta-catenin phosphorylation/degradation by a dual-kinase mechanism

1 reference

https://api.crossref.org/works/10.1002%2FIJC.28341

21 January 2018

Differential roles for the coactivators CBP and p300 on TCF/beta-catenin-mediated survivin gene expression

1 reference

https://api.crossref.org/works/10.1002%2FIJC.28341

21 January 2018

A small molecule inhibitor of beta-catenin/CREB-binding protein transcription [corrected]

1 reference

https://api.crossref.org/works/10.1002%2FIJC.28341

21 January 2018

Wnt/beta-catenin/CBP signaling maintains long-term murine embryonic stem cell pluripotency

1 reference

https://api.crossref.org/works/10.1002%2FIJC.28341

21 January 2018

Symmetric division versus asymmetric division: a tale of two coactivators

1 reference

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21 January 2018

Phenotypic plasticity and epithelial-mesenchymal transitions in cancer and normal stem cells?

1 reference

https://api.crossref.org/works/10.1002%2FIJC.28341

21 January 2018

A temporarily distinct subpopulation of slow-cycling melanoma cells is required for continuous tumor growth

1 reference

https://api.crossref.org/works/10.1002%2FIJC.28341

21 January 2018

Single-cell cloning of colon cancer stem cells reveals a multi-lineage differentiation capacity.

1 reference

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21 January 2018

The beta-catenin axis integrates multiple signals downstream from RET/papillary thyroid carcinoma leading to cell proliferation.

1 reference

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21 January 2018

WNT/beta-catenin mediates radiation resistance of mouse mammary progenitor cells

1 reference

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21 January 2018

Wnt activity defines colon cancer stem cells and is regulated by the microenvironment

1 reference

https://api.crossref.org/works/10.1002%2FIJC.28341

21 January 2018

Maintenance of pluripotency in human and mouse embryonic stem cells through activation of Wnt signaling by a pharmacological GSK-3-specific inhibitor

1 reference

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21 January 2018

The role of PI3K/AKT, MAPK/ERK and NFkappabeta signalling in the maintenance of human embryonic stem cell pluripotency and viability highlighted by transcriptional profiling and functional analysis.

1 reference

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21 January 2018

Activation of Akt signaling is sufficient to maintain pluripotency in mouse and primate embryonic stem cells

1 reference

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21 January 2018

Pten deletion leads to the expansion of a prostatic stem/progenitor cell subpopulation and tumor initiation

1 reference

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21 January 2018

Defining the impact of beta-catenin/Tcf transactivation on epithelial stem cells

1 reference

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Stabilization of beta-catenin by genetic defects in melanoma cell lines

1 reference

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Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

1 reference

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21 January 2018

Genetic and pharmacologic inhibition of β-catenin targets imatinib-resistant leukemia stem cells in CML.

1 reference

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Signaling network crosstalk in human pluripotent cells: a Smad2/3-regulated switch that controls the balance between self-renewal and differentiation

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21 January 2018

PTEN-deficient intestinal stem cells initiate intestinal polyposis

1 reference

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21 January 2018

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