(Q34778710)

4 August 2017

title

PIK3CA activating mutation in colorectal carcinoma: associations with molecular features and survival (English)

1 reference

4 August 2017

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12

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4 August 2017

Elizabeth J Williamson

13

0 references

Christophe Rosty

Christophe Rosty

1

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Daniel D Buchanan

Daniel D Buchanan

15

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Aung Ko Win

Aung Ko Win

9

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Mark Jenkins

Mark A Jenkins

8

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Dallas R. English

Dallas R English

14

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Melissa C. Southey

Melissa C Southey

10

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John Hopper

11

John L Hopper

1 reference

4 August 2017

7

Susan Parry

1 reference

4 August 2017

4

Mark Clendenning

1 reference

4 August 2017

6

Rhiannon J Walters

1 reference

4 August 2017

2

Joanne P Young

1 reference

4 August 2017

Michael D Walsh

3

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4 August 2017

Kristy Sanderson

5

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4 August 2017

language of work or name

English

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publication date

13 June 2013

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4 August 2017

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4 August 2017

volume

8

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4 August 2017

issue

6

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4 August 2017

page(s)

e65479

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Creative Commons Attribution 4.0 International

4 August 2017

copyright license

start time

13 June 2013

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

Colorectal carcinomas with KRAS mutation are associated with distinctive morphological and molecular features

1 reference

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Aspirin use, tumor PIK3CA mutation, and colorectal-cancer survival

7 July 2018

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A combined oncogenic pathway signature of BRAF, KRAS and PI3KCA mutation improves colorectal cancer classification and cetuximab treatment prediction

7 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3681782

PIK3CA mutation and methylation influences the outcome of colorectal cancer

7 July 2018

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KRASness and PIK3CAness in patients with advanced colorectal cancer: outcome after treatment with early-phase trials with targeted pathway inhibitors

7 July 2018

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Phenotype and polyp landscape in serrated polyposis syndrome: a series of 100 patients from genetics clinics

7 July 2018

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Assessment of colorectal cancer molecular features along bowel subsites challenges the conception of distinct dichotomy of proximal versus distal colorectum

7 July 2018

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Prognostic Role of PIK3CA Mutation in Colorectal Cancer: Cohort Study and Literature Review

7 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3681782

PIK3CA exon 20 mutations as a potential biomarker for resistance to anti-EGFR monoclonal antibodies in KRAS wild-type metastatic colorectal cancer: a systematic review and meta-analysis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3681782

PIK3CA mutations frequently coexist with RAS and BRAF mutations in patients with advanced cancers

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3681782

Alterations in PTEN and PIK3CA in colorectal cancers in the EPIC Norfolk study: associations with clinicopathological and dietary factors

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3681782

Phosphorylated AKT expression is associated with PIK3CA mutation, low stage, and favorable outcome in 717 colorectal cancers

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3681782

PIK3CA mutations in patients with advanced cancers treated with PI3K/AKT/mTOR axis inhibitors

7 July 2018

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Hot-spot mutations in p110alpha of phosphatidylinositol 3-kinase (pI3K): differential interactions with the regulatory subunit p85 and with RAS.

7 July 2018

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PIK3CA mutation is associated with poor prognosis among patients with curatively resected colon cancer

7 July 2018

1 reference

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PIK3CA mutation in colorectal cancer: relationship with genetic and epigenetic alterations.

7 July 2018

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PIK3CA mutation/PTEN expression status predicts response of colon cancer cells to the epidermal growth factor receptor inhibitor cetuximab

7 July 2018

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Molecular, pathologic, and clinical features of early-onset endometrial cancer: identifying presumptive Lynch syndrome patients

7 July 2018

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Clinicopathological analysis of colorectal cancers with PIK3CA mutations in Middle Eastern population

7 July 2018

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Mechanism of two classes of cancer mutations in the phosphoinositide 3-kinase catalytic subunit

7 July 2018

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Open-label phase III trial of panitumumab plus best supportive care compared with best supportive care alone in patients with chemotherapy-refractory metastatic colorectal cancer

7 July 2018

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CpG island methylator phenotype underlies sporadic microsatellite instability and is tightly associated with BRAF mutation in colorectal cancer

7 July 2018

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Cancer-specific mutations in PIK3CA are oncogenic in vivo

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3681782

Mutant PIK3CA promotes cell growth and invasion of human cancer cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3681782

Cetuximab monotherapy and cetuximab plus irinotecan in irinotecan-refractory metastatic colorectal cancer

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3681782

High frequency of mutations of the PIK3CA gene in human cancers

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3681782

The phosphoinositol phosphatase activity of PTEN mediates a serum-sensitive G1 growth arrest in glioma cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3681782

Mutant PIK3CA-bearing colon cancer cells display increased metastasis in an orthotopic model.

7 July 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0065479

PIK3CA cancer mutations display gender and tissue specificity patterns.

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0065479

PIK3CA mutations in KRAS and BRAF wild type colorectal cancer patients. A study of Spanish population

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0065479

Characteristics and prevalence of KRAS, BRAF, and PIK3CA mutations in colorectal cancer by high-resolution melting analysis in Taiwanese population.

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0065479

Frequent PIK3CA gene amplification and its clinical significance in colorectal cancer.

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0065479

PIK3CA mutations are not a major determinant of resistance to the epidermal growth factor receptor inhibitor cetuximab in metastatic colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0065479

The prevalence of PIK3CA mutations in gastric and colon cancer.

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0065479

Oncogenic PIK3CA mutations in colorectal cancers and polyps

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0065479

PIK3CA kinase domain mutation identifies a subgroup of stage III colon cancer patients with poor prognosis.

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0065479

Mutations of the PIK3CA gene in hereditary colorectal cancers.

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0065479

Biomarker discovery: identification of a growth factor gene signature

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0065479

Ethnicity and Risk for Colorectal Cancers Showing Somatic BRAF V600E Mutation or CpG Island Methylator Phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0065479

Distinct molecular features of colorectal carcinoma with signet ring cell component and colorectal carcinoma with mucinous component

21 January 2018

1 reference

12 December 2020

Mutation of the PIK3CA gene in ovarian and breast cancer

1 reference

12 December 2020

PIK3CA mutation is predictive of poor survival in patients with colorectal cancer

1 reference

12 December 2020

Poor Survival Associated with theBRAFV600E Mutation in Microsatellite-Stable Colon Cancers

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0065479

Identifiers

DOI

1 reference

release_azx4hzln7ndqzhippnmwrhejmm

4 August 2017

0 references

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/azx4hzln7ndqzhippnmwrhejmm

24 November 2022

mapped directly with Wikidata item

PMC publication ID

3681782

1 reference

4 August 2017

1 reference