(Q34785977)

4 August 2017

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title

In search of authentic inhibitors of HIV-1 integration (English)

1 reference

4 August 2017

1

Zeger Debyser

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Bénédicte Van Maele

series ordinal

3

object named as

Bénédicte Van Maele

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Erik De Clercq

object named as

Erik De Clercq

series ordinal

4

0 references

Peter Cherepanov

series ordinal

2

object named as

Peter Cherepanov

1 reference

4 August 2017

Myriam Witvrouw

5

1 reference

4 August 2017

publication date

1 January 2002

1 reference

Antiviral Chemistry & Chemotherapy

4 August 2017

published in

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4 August 2017

volume

13

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4 August 2017

issue

1

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4 August 2017

page(s)

1-15

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DNA-Dependent protein kinase is not required for efficient lentivirus integration

4 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1177%2F095632020201300101

HIV-1 infection requires a functional integrase NLS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020201300101

HIV-1 preintegration complexes preferentially integrate into longer target DNA molecules in solution as detected by a sensitive, polymerase chain reaction-based integration assay

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020201300101

Correct integration of retroviral DNA in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020201300101

Active nuclear import of human immunodeficiency virus type 1 preintegration complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020201300101

Association of integrase, matrix, and reverse transcriptase antigens of human immunodeficiency virus type 1 with viral nucleic acids following acute infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020201300101

A nuclear localization signal within HIV-1 matrix protein that governs infection of non-dividing cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020201300101

Retroviral DNA integration directed by HIV integration protein in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020201300101

Domains of the integrase protein of human immunodeficiency virus type 1 responsible for polynucleotidyl transfer and zinc binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020201300101

A quantitative assay for HIV DNA integration in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020201300101

Solution structure of the N-terminal zinc binding domain of HIV-1 integrase

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020201300101

Solution structure of the cellular factor BAF responsible for protecting retroviral DNA from autointegration

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020201300101

The barrier-to-autointegration protein is a host factor for HIV type 1 integration

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020201300101

Crystal structure of the HIV-1 integrase catalytic core and C-terminal domains: A model for viral DNA binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020201300101

Mode of interaction of G-quartets with the integrase of human immunodeficiency virus type 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020201300101

Reversal of Integration and DNA Splicing Mediated by Integrase of Human Immunodeficiency Virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020201300101

The IN protein of Moloney murine leukemia virus processes the viral DNA ends and accomplishes their integration in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020201300101

A role for DNA-PK in retroviral DNA integration

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020201300101

Crystal structure of the ribonuclease H domain of HIV-1 reverse transcriptase

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020201300101

Toward improved anti-HIV chemotherapy: therapeutic strategies for intervention with HIV infections

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020201300101

Assays for the evaluation of HIV-1 integrase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020201300101

Cellular Distribution and Karyophilic Properties of Matrix, Integrase, and Vpr Proteins from the Human and Simian Immunodeficiency Viruses

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020201300101

Characterization of the nuclear import pathway for HIV-1 integrase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020201300101

Crystal structure of the catalytic domain of HIV-1 integrase: similarity to other polynucleotidyl transferases

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020201300101

The DNA-binding domain of HIV-1 integrase has an SH3-like fold

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020201300101

HIV-1 integrase inhibitors that compete with the target DNA substrate define a unique strand transfer conformation for integrase

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020201300101

Integration of human immunodeficiency virus type 1 DNA in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020201300101

Differential inhibition of HIV-1 preintegration complexes and purified integrase protein by small molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020201300101

HIV-1 cDNA integration: requirement of HMG I(Y) protein for function of preintegration complexes in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020201300101

Inhibition of HIV-1 integrase by flavones, caffeic acid phenethyl ester (CAPE) and related compounds

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020201300101

Backbone cyclic peptide, which mimics the nuclear localization signal of human immunodeficiency virus type 1 matrix protein, inhibits nuclear import and virus production in nondividing cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020201300101

HIV nuclear import is governed by the phosphotyrosine-mediated binding of matrix to the core domain of integrase

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020201300101

HIV-1 infection of nondividing cells through the recognition of integrase by the importin/karyopherin pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020201300101

Structure of the HIV-1 integrase catalytic domain complexed with an inhibitor: a platform for antiviral drug design

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020201300101

Poly(ADP-ribose) polymerase-1 is required for efficient HIV-1 integration

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020201300101

Integration complexes derived from HIV vectors for rapid assays in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020201300101

Isolation and characterization of novel human immunodeficiency virus integrase inhibitors from fungal metabolites

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020201300101

Inhibitors of strand transfer that prevent integration and inhibit HIV-1 replication in cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020201300101

The Vpr protein of human immunodeficiency virus type 1 influences nuclear localization of viral nucleic acids in nondividing host cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020201300101

Genetic analysis of homomeric interactions of human immunodeficiency virus type 1 integrase using the yeast two-hybrid system

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020201300101

Binding and stimulation of HIV-1 integrase by a human homolog of yeast transcription factor SNF5

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020201300101

The avian retroviral IN protein is both necessary and sufficient for integrative recombination in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020201300101

Targeting of retroviral integrase by fusion to a heterologous DNA binding domain: in vitro activities and incorporation of a fusion protein into viral particles

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020201300101

Retroviral integrase domains: DNA binding and the recognition of LTR sequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020201300101

Residues critical for retroviral integrative recombination in a region that is highly conserved among retroviral/retrotransposon integrases and bacterial insertion sequence transposases

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020201300101

A previously unidentified host protein protects retroviral DNA from autointegration

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020201300101

Zn2+ promotes the self-association of human immunodeficiency virus type-1 integrase in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020201300101

Inhibition of the integrase of human immunodeficiency virus (HIV) type 1 by anti-HIV plant proteins MAP30 and GAP31

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020201300101

Solution structure of the DNA binding domain of HIV-1 integrase

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020201300101

Characterization of the minimal DNA-binding domain of the HIV integrase protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020201300101

In vitro human immunodeficiency virus type 1 integrase assays

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020201300101

Inhibition of the human immunodeficiency virus type 1 integrase by guanosine quartet structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020201300101

Target DNA capture by HIV-1 integration complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020201300101

Structure-function analysis of integrase interactor 1/hSNF5L1 reveals differential properties of two repeat motifs present in the highly conserved region

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020201300101

Salicylhydrazine-containing inhibitors of HIV-1 integrase: implication for a selective chelation in the integrase active site

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020201300101

Thiazolothiazepine inhibitors of HIV-1 integrase

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020201300101

HIV-1 integrase inhibitors: past, present, and future

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020201300101

T30177, an oligonucleotide stabilized by an intramolecular guanosine octet, is a potent inhibitor of laboratory strains and clinical isolates of human immunodeficiency virus type 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020201300101

The karyophilic properties of human immunodeficiency virus type 1 integrase are not required for nuclear import of proviral DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020201300101

Nuclear localization of human immunodeficiency virus type 1 integrase expressed as a fusion protein with green fluorescent protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020201300101

Retroviral integrase inhibitors year 2000: update and perspectives

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020201300101

Critical role of reverse transcriptase in the inhibitory mechanism of CNI-H0294 on HIV-1 nuclear translocation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020201300101

Viral protein R regulates nuclear import of the HIV-1 pre-integration complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020201300101

Suppression of human immunodeficiency virus type 1 activity in vitro by oligonucleotides which form intramolecular tetrads

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020201300101

Retroviral integrases and their cousins

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020201300101

Structure of the bacteriophage Mu transposase core: a common structural motif for DNA transposition and retroviral integration

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020201300101

Human immunodeficiency virus integration protein expressed in Escherichia coli possesses selective DNA cleaving activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020201300101

Cytoplasmic recruitment of INI1 and PML on incoming HIV preintegration complexes: interference with early steps of viral replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020201300101

Structural basis of DNA bridging by barrier-to-autointegration factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020201300101

Specific inhibition of human immunodeficiency virus type 1 (HIV-1) integration in cell culture: putative inhibitors of HIV-1 integrase

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020201300101

Mutational analysis of the integrase protein of human immunodeficiency virus type 2

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020201300101

Identification of the catalytic and DNA-binding region of the human immunodeficiency virus type I integrase protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020201300101

4-Aryl-2,4-dioxobutanoic acid inhibitors of HIV-1 integrase and viral replication in cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020201300101

Structure of a two-domain fragment of HIV-1 integrase: implications for domain organization in the intact protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020201300101

An inhibitory monoclonal antibody binds at the turn of the helix-turn-helix motif in the N-terminal domain of HIV-1 integrase

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020201300101

Repair of gaps in retroviral DNA integration intermediates

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020201300101

Inhibition of HIV-1 virion production by a transdominant mutant of integrase interactor 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020201300101

Hydrazide-containing inhibitors of HIV-1 integrase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020201300101

Zinc folds the N-terminal domain of HIV-1 integrase, promotes multimerization, and enhances catalytic activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F095632020201300101

10.1177/095632020201300101

21 January 2018

Identifiers

DOI

1 reference

4 August 2017

1 reference