(Q34795980)

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A narrow repertoire of transcriptional modules responsive to pyogenic bacteria is impaired in patients carrying loss-of-function mutations in MYD88 or IRAK4

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Europe PubMed Central

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4 August 2017

A narrow repertoire of transcriptional modules responsive to pyogenic bacteria is impaired in patients carrying loss-of-function mutations in MYD88 or IRAK4 (English)

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Europe PubMed Central

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4 August 2017

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4 August 2017

Capucine Picard

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4 August 2017

Jean-Laurent Casanova

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4 August 2017

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Pegah Ghandil

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Laia Alsina

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Damien Chaussabel

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Damien Chaussabel

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Laurent Abel

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Horst von Bernuth

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Horst von Bernuth

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4 August 2017

Elisabeth Israelsson

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Elisabeth Israelsson

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4 August 2017

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Matthew C Altman

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4 August 2017

Kristen K Dang

4

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4 August 2017

Laura Israel

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4 August 2017

Nicole Baldwin

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4 August 2017

Huanying Qin

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4 August 2017

Zongbo Jin

10

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4 August 2017

Romain Banchereau

11

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4 August 2017

Esperanza Anguiano

12

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4 August 2017

Alexei Ionan

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4 August 2017

Virginia Pascual

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4 August 2017

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publication date

26 October 2014

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4 August 2017

Nature Immunology

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4 August 2017

15

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4 August 2017

12

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4 August 2017

1134-1142

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Europe PubMed Central

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4 August 2017

Democratizing systems immunology with modular transcriptional repertoire analyses

1 reference

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8 July 2018

Immunoresponsive gene 1 augments bactericidal activity of macrophage-lineage cells by regulating β-oxidation-dependent mitochondrial ROS production

1 reference

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8 July 2018

Systems scale interactive exploration reveals quantitative and qualitative differences in response to influenza and pneumococcal vaccines

1 reference

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8 July 2018

Acyl-CoA synthetase 1 is induced by Gram-negative bacteria and lipopolysaccharide and is required for phospholipid turnover in stimulated macrophages

1 reference

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8 July 2018

Experimental and natural infections in MyD88- and IRAK-4-deficient mice and humans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281021

8 July 2018

Host immune transcriptional profiles reflect the variability in clinical disease manifestations in patients with Staphylococcus aureus infections

1 reference

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Nijmegen breakage syndrome (NBS)

1 reference

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8 July 2018

Accessory molecules for Toll-like receptors and their function

1 reference

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8 July 2018

Recognition of Streptococcus pneumoniae by the innate immune system.

1 reference

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8 July 2018

E4BP4: an unexpected player in the immune response

1 reference

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Herpes simplex virus encephalitis in a patient with complete TLR3 deficiency: TLR3 is otherwise redundant in protective immunity

1 reference

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8 July 2018

Infectious diseases in patients with IRAK-4, MyD88, NEMO, or IκBα deficiency

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281021

8 July 2018

Role of CLIC4 in the host innate responses to bacterial lipopolysaccharide

1 reference

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8 July 2018

Human TLRs and IL-1Rs in host defense: natural insights from evolutionary, epidemiological, and clinical genetics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281021

8 July 2018

Clinical features and outcome of patients with IRAK-4 and MyD88 deficiency

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281021

8 July 2018

Dual function of MyD88 in RAS signaling and inflammation, leading to mouse and human cell transformation

1 reference

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8 July 2018

An interferon-inducible neutrophil-driven blood transcriptional signature in human tuberculosis

1 reference

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8 July 2018

Helical assembly in the MyD88–IRAK4–IRAK2 complex in TLR/IL-1R signalling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281021

8 July 2018

The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors

1 reference

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8 July 2018

A genomic approach to human autoimmune diseases

1 reference

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8 July 2018

Mechanisms of immunosenescence

1 reference

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8 July 2018

Circos: an information aesthetic for comparative genomics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281021

8 July 2018

Cross-regulation of signaling by ITAM-associated receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281021

8 July 2018

Inborn errors of interferon (IFN)-mediated immunity in humans: insights into the respective roles of IFN-alpha/beta, IFN-gamma, and IFN-lambda in host defense

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281021

8 July 2018

Function of Nod-like receptors in microbial recognition and host defense

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281021

8 July 2018

Pyogenic bacterial infections in humans with MyD88 deficiency

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281021

8 July 2018

Requirement of TLR2-mediated signaling for the induction of IL-15 gene expression in human monocytic cells by HSV-1

1 reference

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8 July 2018

The TLR2-MyD88-NOD2-RIPK2 signalling axis regulates a balanced pro-inflammatory and IL-10-mediated anti-inflammatory cytokine response to Gram-positive cell walls

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281021

8 July 2018

Microarray-based identification of novel biomarkers in IL-1-mediated diseases

1 reference

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8 July 2018

Selective predisposition to bacterial infections in IRAK-4-deficient children: IRAK-4-dependent TLRs are otherwise redundant in protective immunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281021

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IkappaB genetic polymorphisms and invasive pneumococcal disease

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The role of TLR2 in vivo following challenge with Staphylococcus aureus and prototypic ligands

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Gene expression patterns in blood leukocytes discriminate patients with acute infections

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Adjusting batch effects in microarray expression data using empirical Bayes methods

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Pathogen recognition and innate immunity

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Microarray data analysis: from disarray to consolidation and consensus

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Synergistic effect of Nod1 and Nod2 agonists with toll-like receptor agonists on human dendritic cells to generate interleukin-12 and T helper type 1 cells

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Selective impairment of TLR-mediated innate immunity in human newborns: neonatal blood plasma reduces monocyte TNF-alpha induction by bacterial lipopeptides, lipopolysaccharide, and imiquimod, but preserves the response to R-848.

1 reference

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Staphylococcus aureus protein A induces airway epithelial inflammatory responses by activating TNFR1

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Primary immunodeficiencies associated with pneumococcal disease

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Cumulative Toll-Like Receptor Activation in Human Macrophages Treated with Whole Bacteria

1 reference

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Pyogenic bacterial infections in humans with IRAK-4 deficiency

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281021

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Role of neutrophil leukocytes in cutaneous infection caused by Staphylococcus aureus

1 reference

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1 reference

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MyD88 mediates neutrophil recruitment initiated by IL-1R but not TLR2 activation in immunity against Staphylococcus aureus

1 reference

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Critical role of signaling through IL-1 receptor for development of arthritis and sepsis during Staphylococcus aureus infection.

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IL-1 and TNF-alpha play a pivotal role in the host immune response in a mouse model of Staphylococcus aureus-induced experimental brain abscess

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Antibodies to proteinase 3 prime human monocytic cells via protease-activated receptor-2 and NF-kappaB for Toll-like receptor- and NOD-dependent activation

1 reference

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Various human epithelial cells express functional Toll-like receptors, NOD1 and NOD2 to produce anti-microbial peptides, but not proinflammatory cytokines

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chronic pneumonia despite adaptive immune response to Mycobacterium bovis BCG in MyD88-deficient mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/25344726

12 December 2020

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Solving vaccine mysteries: a systems biology perspective

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https://pubmed.ncbi.nlm.nih.gov/25344726

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10.1038/NI.3028

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

PMC publication ID

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Europe PubMed Central

PubMed publication ID

4 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

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